102 items (Penicillium subrubescens) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	PENSUB_6919	Lipoyl-binding domain-containing protein. (451 aa)
	PENSUB_13753	Homoserine kinase. (355 aa)
	PENSUB_13453	HTH APSES-type domain-containing protein. (512 aa)
	PENSUB_13331	Alanine racemase TOXG. (331 aa)
	PENSUB_13087	Hippurate hydrolase. (420 aa)
	PENSUB_13061	Uncharacterized protein. (83 aa)
	PENSUB_13060	O-acetylhomoserine (Thiol)-lyase. (104 aa)
	PENSUB_13059	O-acetylhomoserine (Thiol)-lyase. (147 aa)
	PENSUB_13002	Fungal_trans domain-containing protein. (641 aa)
	MDE1	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (245 aa)
	PENSUB_12294	Monomeric sarcosine oxidase. (426 aa)
	PENSUB_12469	Zn(2)-C6 fungal-type domain-containing protein. (727 aa)
	PENSUB_12388	Zn(2)-C6 fungal-type domain-containing protein. (662 aa)
	PENSUB_11960	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (480 aa)
	PENSUB_12136	Uncharacterized protein. (100 aa)
	PENSUB_12187	L-serine dehydratase. (356 aa)
	PENSUB_12218	Homoserine dehydrogenase. (380 aa)
	PENSUB_11598	Low-specificity L-threonine aldolase. (371 aa)
	PENSUB_11856	Aspartate aminotransferase. (412 aa)
	PENSUB_11517	Beta_elim_lyase domain-containing protein. (259 aa)
	PENSUB_11370	Aconitate hydratase, mitochondrial. (468 aa)
	PENSUB_11068	Aspartate aminotransferase, cytoplasmic. (419 aa)
	PENSUB_11089	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
	PENSUB_11168	Uncharacterized protein. (768 aa)
	PENSUB_11219	Alcohol dehydrogenase 1. (350 aa)
	PENSUB_11218	Regulatory protein alcR. (811 aa)
	PENSUB_10958	Asparagine synthetase [glutamine-hydrolyzing] 2. (531 aa)
	PENSUB_10623	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (612 aa)
	PENSUB_10686	Beta_elim_lyase domain-containing protein. (403 aa)
	PENSUB_10048	Threonine synthase. (535 aa)
	PENSUB_10027	L-saccharopine oxidase. (446 aa)
	PENSUB_10139	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (488 aa)
	PENSUB_10173	Semialdhyde_dhC domain-containing protein. (267 aa)
	PENSUB_10174	Aspartate-semialdehyde dehydrogenase. (106 aa)
	PENSUB_10341	Zn(2)-C6 fungal-type domain-containing protein. (789 aa)
	PENSUB_9885	Isochorismatase domain-containing protein. (205 aa)
	PENSUB_9698	Zn(2)-C6 fungal-type domain-containing protein. (697 aa)
	PENSUB_9579	L-pipecolate oxidase. (447 aa)
	PENSUB_9578	Fungal_trans domain-containing protein. (576 aa)
	PENSUB_9617	Homoserine dehydrogenase. (530 aa)
	PENSUB_9290	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (309 aa)
	PENSUB_9408	Uncharacterized protein. (482 aa)
	PENSUB_9433	L-pipecolate oxidase. (429 aa)
	PENSUB_9434	Uncharacterized protein. (253 aa)
	PENSUB_9205	Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (782 aa)
	PENSUB_8761	Uncharacterized protein. (63 aa)
	PENSUB_8796	Homoserine dehydrogenase. (370 aa)
	PENSUB_8801	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (376 aa)
	PENSUB_8863	Uncharacterized protein. (559 aa)
	PENSUB_8636	Cystathionine beta-lyase. (442 aa)
	PENSUB_8682	Meth_synt_2 domain-containing protein. (402 aa)
	PENSUB_8130	L-pipecolate oxidase. (348 aa)
	PENSUB_8176	Alcohol dehydrogenase 1. (352 aa)
	PENSUB_7790	L-serine dehydratase. (473 aa)
	PENSUB_7826	Threonine dehydratase. (566 aa)
	PENSUB_7901	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
	PENSUB_7667	L-pipecolate oxidase. (445 aa)
	PENSUB_7587	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (690 aa)
	PENSUB_7336	Uncharacterized protein. (360 aa)
	PENSUB_1778	Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (211 aa)
	PENSUB_1573	Asparagine synthetase domain-containing protein C4F6.11c. (352 aa)
	PENSUB_1585	Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]. (450 aa)
	PENSUB_1234	Hippurate hydrolase. (264 aa)
	PENSUB_724	Aspartate aminotransferase. (431 aa)
	PENSUB_856	Aspartate aminotransferase. (417 aa)
	PENSUB_880	L-saccharopine oxidase. (436 aa)
	PENSUB_585	Low specificity L-threonine aldolase. (370 aa)
	PENSUB_450	Epimerase domain-containing protein. (317 aa)
	PENSUB_31	Uncharacterized protein. (301 aa)
	PENSUB_14088	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (390 aa)
	PENSUB_5835	Homoisocitrate dehydrogenase. (361 aa)
	ADI1	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (178 aa)
	PENSUB_3382	annotation not available (225 aa)
	PENSUB_7008	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (496 aa)
	PENSUB_6929	Cystathionine gamma-synthase. (572 aa)
	MRI1	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (386 aa)
	PENSUB_6789	L-pipecolate oxidase. (438 aa)
	PENSUB_6560	Aldehyde dehydrogenase family 1 member A3; Belongs to the aldehyde dehydrogenase family. (503 aa)
	PENSUB_6579	Uncharacterized protein. (291 aa)
	PENSUB_6620	Aldehyde dehydrogenase 5, mitochondrial; Belongs to the aldehyde dehydrogenase family. (481 aa)
	PENSUB_6335	Epimerase domain-containing protein. (322 aa)
	PENSUB_5435	Homoserine O-acetyltransferase. (492 aa)
	PENSUB_5251	O-acetylhomoserine (Thiol)-lyase. (439 aa)
	PENSUB_4748	Uncharacterized protein. (125 aa)
	PENSUB_4741	Homocysteine S-methyltransferase 1. (345 aa)
	PENSUB_4456	L-saccharopine oxidase. (351 aa)
	PENSUB_4369	Uncharacterized protein. (158 aa)
	PENSUB_4238	Uncharacterized protein. (452 aa)
	PENSUB_3760	ACPS domain-containing protein. (408 aa)
	PENSUB_3481	Uncharacterized protein. (200 aa)
	PENSUB_3194	Hydrolase C26A3.11. (294 aa)
	PENSUB_3212	8-amino-7-oxononanoate synthase. (420 aa)
	PENSUB_3247	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (787 aa)
	PENSUB_3159	Phosphoadenosine phosphosulfate reductase. (308 aa)
	PENSUB_3117	Meth_synt_2 domain-containing protein. (408 aa)
	MET3	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (574 aa)
	PENSUB_2858	Alanine racemase TOXG. (381 aa)
	PENSUB_2835	Aldehyde dehydrogenase. (504 aa)
	PENSUB_2728	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (502 aa)
	PENSUB_2762	Homocitrate synthase, mitochondrial; Belongs to the alpha-IPM synthase/homocitrate synthase family. (465 aa)
	PENSUB_2767	Aspartate aminotransferase. (429 aa)
	PENSUB_2826	FAD-binding FR-type domain-containing protein. (642 aa)

Your Current Organism:

Penicillium subrubescens

NCBI taxonomy Id: 1316194
Other names: CBS 132785, CBS H-21029, DTO 188-D6, IBT 31985, P. subrubescens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADI1	MDE1	A0A1Q5UR13	A0A1Q5SXJ0	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).	0.968
ADI1	MRI1	A0A1Q5UR13	A0A1Q5TT43	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	0.662
ADI1	PENSUB_10623	A0A1Q5UR13	A0A1Q5T8D3	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.662
ADI1	PENSUB_11068	A0A1Q5UR13	A0A1Q5T5N6	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aspartate aminotransferase, cytoplasmic.	0.574
ADI1	PENSUB_11856	A0A1Q5UR13	A0A1Q5T2X8	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aspartate aminotransferase.	0.574
ADI1	PENSUB_2767	A0A1Q5UR13	A0A1Q5UGT4	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aspartate aminotransferase.	0.574
ADI1	PENSUB_4741	A0A1Q5UR13	A0A1Q5UBH5	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Homocysteine S-methyltransferase 1.	0.650
ADI1	PENSUB_724	A0A1Q5UR13	A0A1Q5UM58	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aspartate aminotransferase.	0.574
ADI1	PENSUB_7587	A0A1Q5UR13	A0A1Q5TLA4	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.	0.662
ADI1	PENSUB_856	A0A1Q5UR13	A0A1Q5UME8	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	Aspartate aminotransferase.	0.574
ADI1	PENSUB_9290	A0A1Q5UR13	A0A1Q5TD98	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.461
MDE1	ADI1	A0A1Q5SXJ0	A0A1Q5UR13	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).	0.968
MDE1	MRI1	A0A1Q5SXJ0	A0A1Q5TT43	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.	0.973
MDE1	PENSUB_4741	A0A1Q5SXJ0	A0A1Q5UBH5	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).	Homocysteine S-methyltransferase 1.	0.574
MDE1	PENSUB_4748	A0A1Q5SXJ0	A0A1Q5UBG7	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).	Uncharacterized protein.	0.864
MDE1	PENSUB_9290	A0A1Q5SXJ0	A0A1Q5TD98	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.787
MET3	PENSUB_10958	A0A1Q5UG94	A0A1Q5T6Q6	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	Asparagine synthetase [glutamine-hydrolyzing] 2.	0.477
MET3	PENSUB_11168	A0A1Q5UG94	A0A1Q5T5Z2	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	Uncharacterized protein.	0.504
MET3	PENSUB_14088	A0A1Q5UG94	A0A1Q5UPB4	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.	0.525
MET3	PENSUB_1778	A0A1Q5UG94	A0A1Q5UJL6	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family.	Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.	0.994