(60 nodes) Extrinsic component of membrane network (Penicillium subrubescens)

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	PENSUB_1900	Nitrogen permease regulator 2-like protein. (786 aa)
	PENSUB_7305	Target of rapamycin complex subunit LST8. (538 aa)
	PENSUB_7034	Uncharacterized protein. (1590 aa)
	PENSUB_6279	COX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family. (141 aa)
	PENSUB_6355	Phosphatidate cytidylyltransferase, mitochondrial. (406 aa)
	PENSUB_6409	Regulator of V-ATPase in vacuolar membrane protein 1. (1335 aa)
	PENSUB_6493	Guanine nucleotide-binding protein subunit alpha. (342 aa)
	PENSUB_5165	Uncharacterized protein. (394 aa)
	PENSUB_4930	SVP1-like protein 2. (316 aa)
	PENSUB_4946	Phosphatidylinositol 3-kinase VPS34. (904 aa)
	PENSUB_4670	GTPase MTG2, mitochondrial. (567 aa)
	PENSUB_11534	Methyltransf_25 domain-containing protein. (58 aa)
	PENSUB_4315	Uncharacterized protein. (403 aa)
	PENSUB_4220	Glucose-induced degradation protein 4-like protein. (315 aa)
	PENSUB_3952	Guanine nucleotide-binding protein subunit beta. (415 aa)
	PENSUB_3339	Zn(2)-C6 fungal-type domain-containing protein. (323 aa)
	PENSUB_3328	Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (453 aa)
	PENSUB_3252	Protein VAC14-like protein. (976 aa)
	PENSUB_3281	Uncharacterized protein. (247 aa)
	PENSUB_3063	Maltose fermentation regulatory protein. (585 aa)
	PENSUB_2967	Uncharacterized protein. (258 aa)
	COQ4	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (287 aa)
	PENSUB_3005	Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (449 aa)
	PENSUB_13787	GTP-binding protein rhb1. (187 aa)
	PENSUB_13201	Uncharacterized protein. (136 aa)
	PENSUB_13037	Chitin synthase export chaperone. (230 aa)
	COQ6	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (509 aa)
	COQ3	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (349 aa)
	PENSUB_1607	Vacuolar protein sorting-associated protein; May be involved in recycling of membrane proteins between an endocytic compartment and the TGN; Belongs to the VPS13 family. (3165 aa)
	COQ5	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (315 aa)
	PENSUB_958	Polyphosphoinositide phosphatase. (994 aa)
	PENSUB_12445	Protein msp1, mitochondrial; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (916 aa)
	PENSUB_12112	Vacuolar protein sorting-associated protein 74. (360 aa)
	PENSUB_644	Uncharacterized protein. (345 aa)
	PENSUB_566	Vacuolar segregation protein 7. (922 aa)
	PENSUB_13957	Uncharacterized protein. (104 aa)
	PENSUB_5842	1-phosphatidylinositol 3-phosphate 5-kinase FAB1. (2514 aa)
	PENSUB_5915	Uncharacterized protein. (281 aa)
	PENSUB_5079	Protein ABC1-like protein, mitochondrial. (746 aa)
	PENSUB_11511	Guanine nucleotide-binding protein alpha-3 subunit. (71 aa)
	PENSUB_11288	Uncharacterized protein. (121 aa)
	PENSUB_11160	Tether containing UBX domain for GLUT4. (505 aa)
	PENSUB_10701	DnaJ-like protein, mitochondrial. (501 aa)
	PENSUB_10836	Zn(2)-C6 fungal-type domain-containing protein. (553 aa)
	PENSUB_10032	Uncharacterized protein. (727 aa)
	PENSUB_10062	Actin patches distal protein 1. (295 aa)
	COQ7	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (245 aa)
	PENSUB_9677	Guanine nucleotide-binding protein alpha-3 subunit. (356 aa)
	PENSUB_9183	Altered inheritance of mitochondria protein 32. (308 aa)
	PENSUB_9207	Cytochrome c mitochondrial import factor CYC2. (402 aa)
	PENSUB_8790	Autophagy-related protein 11. (1332 aa)
	PENSUB_8907	Guanine nucleotide-binding protein alpha-2 subunit. (358 aa)
	PENSUB_8684	Uncharacterized protein. (273 aa)
	PENSUB_8683	F-box domain-containing protein. (359 aa)
	PENSUB_8716	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (193 aa)
	PENSUB_8408	Protein UPS1, mitochondrial. (267 aa)
	PENSUB_7994	Protein MSS51, mitochondrial. (519 aa)
	PENSUB_7498	Uncharacterized protein. (1711 aa)
	PENSUB_7547	Uncharacterized protein. (125 aa)
	PENSUB_7270	Nitrogen permease regulator 3. (851 aa)

Your Current Organism:

Penicillium subrubescens

NCBI taxonomy Id: 1316194
Other names: CBS 132785, CBS H-21029, DTO 188-D6, IBT 31985, P. subrubescens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COQ3	COQ4	A0A1Q5UGY4	A0A1Q5UG91	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	0.808
COQ3	COQ5	A0A1Q5UGY4	A0A1Q5UL60	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.827
COQ3	COQ6	A0A1Q5UGY4	A0A1Q5SXK6	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.981
COQ3	COQ7	A0A1Q5UGY4	A0A1Q5TAZ6	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.	0.964
COQ3	PENSUB_11288	A0A1Q5UGY4	A0A1Q5T4Q8	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Uncharacterized protein.	0.970
COQ3	PENSUB_3005	A0A1Q5UGY4	A0A1Q5UGD3	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	0.475
COQ3	PENSUB_3328	A0A1Q5UGY4	A0A1Q5UFB1	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Uncharacterized protein; Belongs to the FPP/GGPP synthase family.	0.475
COQ3	PENSUB_5079	A0A1Q5UGY4	A0A1Q5UR37	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	Protein ABC1-like protein, mitochondrial.	0.912
COQ4	COQ3	A0A1Q5UG91	A0A1Q5UGY4	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.808
COQ4	COQ5	A0A1Q5UG91	A0A1Q5UL60	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	0.703
COQ4	COQ6	A0A1Q5UG91	A0A1Q5SXK6	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.	0.772
COQ4	COQ7	A0A1Q5UG91	A0A1Q5TAZ6	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	5-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.	0.685
COQ4	PENSUB_10836	A0A1Q5UG91	A0A1Q5T8U5	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Zn(2)-C6 fungal-type domain-containing protein.	0.562
COQ4	PENSUB_11288	A0A1Q5UG91	A0A1Q5T4Q8	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Uncharacterized protein.	0.617
COQ4	PENSUB_11534	A0A1Q5UG91	A0A1Q5UCG9	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Methyltransf_25 domain-containing protein.	0.562
COQ4	PENSUB_3063	A0A1Q5UG91	A0A1Q5UFX4	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Maltose fermentation regulatory protein.	0.562
COQ4	PENSUB_3281	A0A1Q5UG91	A0A1Q5UFL4	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Uncharacterized protein.	0.562
COQ4	PENSUB_3339	A0A1Q5UG91	A0A1Q5UFA2	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Zn(2)-C6 fungal-type domain-containing protein.	0.562
COQ4	PENSUB_5079	A0A1Q5UG91	A0A1Q5UR37	Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family.	Protein ABC1-like protein, mitochondrial.	0.682
COQ5	COQ3	A0A1Q5UL60	A0A1Q5UGY4	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2).	Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.	0.827