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fumC fumC PU02_0366 PU02_0366 PU02_0367 PU02_0367 PU02_0368 PU02_0368 PU02_0369 PU02_0369 PU02_0430 PU02_0430 PU02_0431 PU02_0431 PU02_0432 PU02_0432 sucD sucD sucC sucC mdh mdh PU02_0539 PU02_0539 PU02_0556 PU02_0556 prs prs PU02_0904 PU02_0904 PU02_1050 PU02_1050 gltA gltA PU02_1121 PU02_1121 PU02_1122 PU02_1122 PU02_1123 PU02_1123 pdhA pdhA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (462 aa)
PU02_0366Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa)
PU02_0367Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (614 aa)
PU02_0368Succinate dehydrogenase hydrophobic membrane anchor protein. (128 aa)
PU02_0369Succinate dehydrogenase cytochrome b-556 subunit. (133 aa)
PU02_0430Dihydrolipoamide dehydrogenase of 2-oxoglutarate dehydrogenase. (468 aa)
PU02_0431Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (400 aa)
PU02_04322-oxoglutarate dehydrogenase E1 component. (1001 aa)
sucDSuccinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa)
sucCSuccinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (398 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
PU02_0539NADP-dependent malic enzyme. (441 aa)
PU02_0556Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (895 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (310 aa)
PU02_0904Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (400 aa)
PU02_1050NADP-dependent malic enzyme. (784 aa)
gltACitrate synthase (si); Belongs to the citrate synthase family. (434 aa)
PU02_1121Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex. (494 aa)
PU02_1122Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (437 aa)
PU02_1123Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (454 aa)
pdhAPyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (350 aa)
Your Current Organism:
Bartonella ancashensis
NCBI taxonomy Id: 1318743
Other names: ATCC BAA-2694, B. ancashensis, Bartonella ancashensis Mullins et al. 2015, Bartonella sp. 20.60, Candidatus Bartonella ancashi, DSM 29364, strain 20-00, strain 20.00
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