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argG argG BN4_20509 BN4_20509 carA carA guaA guaA BN4_20301 BN4_20301 BN4_20032 BN4_20032 BN4_20016 BN4_20016 argC argC BN4_12690 BN4_12690 cobB-2 cobB-2 BN4_12603 BN4_12603 BN4_12550 BN4_12550 BN4_12548 BN4_12548 BN4_12189 BN4_12189 BN4_12166 BN4_12166 BN4_12143 BN4_12143 BN4_12067 BN4_12067 glnA-2 glnA-2 BN4_11987 BN4_11987 rocD rocD cobB cobB BN4_11930 BN4_11930 argJ argJ cobDQ cobDQ BN4_11516 BN4_11516 argB argB proB proB BN4_11172 BN4_11172 proA proA carB carB purF purF BN4_10854 BN4_10854 argF argF argH argH BN4_10686 BN4_10686 speA speA pyrG pyrG proC proC argD argD BN4_10503 BN4_10503 BN4_10502 BN4_10502 BN4_10501 BN4_10501 hisH hisH BN4_10071 BN4_10071 BN4_10070 BN4_10070
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (410 aa)
BN4_20509Aldehyde Dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. (1005 aa)
carACarbamoyl-phosphate synthase small chain; Belongs to the CarA family. (374 aa)
guaAGMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. (514 aa)
BN4_20301GCN5-related N-acetyltransferase. (159 aa)
BN4_20032Glutamine amidotransferase class-I. (234 aa)
BN4_20016FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (409 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (351 aa)
BN4_12690Asparagine synthase (Glutamine-hydrolyzing). (623 aa)
cobB-2Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (467 aa)
BN4_12603Dimethylargininase. (252 aa)
BN4_12550Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the acetyltransferase family. (152 aa)
BN4_12548Glutamine amidotransferase class-I. (240 aa)
BN4_12189Asparagine synthase (Glutamine-hydrolyzing). (676 aa)
BN4_12166Homologs of previously reported genes of unknown function. (320 aa)
BN4_12143Homologs of previously reported genes of unknown function. (387 aa)
BN4_12067Putative amidotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (644 aa)
glnA-2Glutamine synthetase. (447 aa)
BN4_11987Glutamate synthase (NADPH), homotetrameric. (472 aa)
rocDOrnithine aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (399 aa)
cobBCobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (467 aa)
BN4_11930Proline dehydrogenase. (315 aa)
argJArginine biosynthesis bifunctional protein ArgJ [Includes: Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (393 aa)
cobDQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (895 aa)
BN4_11516Glutamine--fructose-6-phosphate transaminase (Isomerizing). (941 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (310 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (386 aa)
BN4_11172GCN5-related N-acetyltransferase. (287 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (419 aa)
carBCarbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1078 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (471 aa)
BN4_10854Glu/Leu/Phe/Val dehydrogenase. (984 aa)
argFOrnithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (300 aa)
argHArgininosuccinate lyase. (462 aa)
BN4_10686Agmatinase; Belongs to the arginase family. (284 aa)
speABiosynthetic arginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily. (637 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (547 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (266 aa)
argDAcetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (406 aa)
BN4_10503Glutamate synthase; Belongs to the glutamate synthase family. (421 aa)
BN4_10502Homologs of previously reported genes of unknown function. (365 aa)
BN4_10501Homologs of previously reported genes of unknown function. (253 aa)
hisHImidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (213 aa)
BN4_10071Ferredoxin-dependent glutamate synthase; Belongs to the glutamate synthase family. (544 aa)
BN4_10070Glutamate synthase (NADPH). (378 aa)
Your Current Organism:
Pseudodesulfovibrio piezophilus
NCBI taxonomy Id: 1322246
Other names: Desulfovibrio piezophilus C1TLV30, Desulfovibrio piezophilus DSM 21447, Desulfovibrio piezophilus JCM 15486, Desulfovibrio sp. C1TLV30, P. piezophilus C1TLV30, Pseudodesulfovibrio piezophilus C1TLV30, Pseudodesulfovibrio piezophilus DSM 21447, Pseudodesulfovibrio piezophilus JCM 15486
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