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kdsB kdsB BN4_10011 BN4_10011 BN4_10043 BN4_10043 BN4_10058 BN4_10058 BN4_10059 BN4_10059 BN4_10082 BN4_10082 BN4_10083 BN4_10083 rmlA rmlA BN4_10100 BN4_10100 gpmA gpmA lpxC lpxC lpxD lpxD fabZ fabZ lpxA lpxA BN4_10204 BN4_10204 BN4_10259 BN4_10259 BN4_10310 BN4_10310 fbp fbp BN4_10414 BN4_10414 BN4_10419 BN4_10419 BN4_10420 BN4_10420 tpiA tpiA udg udg kdsC kdsC kdsA kdsA sdaA sdaA algA algA BN4_10651 BN4_10651 BN4_10697 BN4_10697 BN4_10714 BN4_10714 BN4_10819 BN4_10819 BN4_10820 BN4_10820 BN4_10824 BN4_10824 BN4_10959 BN4_10959 BN4_10978 BN4_10978 BN4_10980 BN4_10980 BN4_10981 BN4_10981 BN4_11009 BN4_11009 BN4_11041 BN4_11041 lpxB lpxB BN4_11057 BN4_11057 yvgN yvgN opgG opgG opgH opgH BN4_11227 BN4_11227 BN4_11355 BN4_11355 BN4_11359 BN4_11359 BN4_11364 BN4_11364 BN4_11390 BN4_11390 capL capL BN4_11817 BN4_11817 BN4_11846 BN4_11846 BN4_11922 BN4_11922 BN4_11964 BN4_11964 BN4_11980 BN4_11980 BN4_12004 BN4_12004 BN4_12005 BN4_12005 BN4_12061 BN4_12061 BN4_12080 BN4_12080 BN4_12085 BN4_12085 BN4_12087 BN4_12087 BN4_12125 BN4_12125 BN4_12142 BN4_12142 BN4_12227 BN4_12227 BN4_12381 BN4_12381 BN4_12415 BN4_12415 yggF yggF glmU glmU BN4_12589 BN4_12589 BN4_12645 BN4_12645 otsA otsA BN4_12664 BN4_12664 BN4_12680 BN4_12680 BN4_12686 BN4_12686 BN4_12687 BN4_12687 BN4_12688 BN4_12688 BN4_12692 BN4_12692 BN4_12694 BN4_12694 lpxK lpxK BN4_12738 BN4_12738 BN4_12822 BN4_12822 BN4_20024 BN4_20024 BN4_20043 BN4_20043 BN4_20047 BN4_20047 BN4_20048 BN4_20048 BN4_20088 BN4_20088 BN4_20163 BN4_20163 BN4_20183 BN4_20183 BN4_20185 BN4_20185 BN4_20341 BN4_20341 BN4_20358 BN4_20358 BN4_20361 BN4_20361 BN4_20441 BN4_20441
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (246 aa)
BN4_10011Glycosyl transferase family 2. (531 aa)
BN4_10043Glycosyl transferase family 9. (517 aa)
BN4_10058Glycosyl transferase family 9. (349 aa)
BN4_10059Protein of unknown function; No homology to any previously reported sequences. (72 aa)
BN4_10082Putative glycosyltransferase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (375 aa)
BN4_10083Putative glycosyltransferase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (354 aa)
rmlAGlucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (296 aa)
BN4_10100Glycosyl transferase group 1. (403 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (248 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (306 aa)
lpxDUDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (348 aa)
fabZ(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (152 aa)
lpxAAcyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (270 aa)
BN4_10204Homologs of previously reported genes of unknown function. (277 aa)
BN4_10259Homologs of previously reported genes of unknown function. (220 aa)
BN4_10310Homologs of previously reported genes of unknown function. (328 aa)
fbpFructose-1,6-bisphosphatase class 1. (343 aa)
BN4_10414Glycosyl transferase group 1. (352 aa)
BN4_10419Carbamoyl-phosphate synthase L chain ATP-binding. (1236 aa)
BN4_10420Pyruvate phosphate dikinase PEP/pyruvate-binding. (1196 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (257 aa)
udgUDP-glucose 6-dehydrogenase. (445 aa)
kdsC3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (175 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (269 aa)
sdaAL-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (453 aa)
algAAlginate biosynthesis protein AlgA [Includes: Mannose-6-phosphate isomerase; Mannose-1-phosphate guanylyltransferase]; Belongs to the mannose-6-phosphate isomerase type 2 family. (476 aa)
BN4_10651Fucose 4-O-acetylase and related acetyltransferase-like protein. (371 aa)
BN4_10697Pyruvate, water dikinase. (863 aa)
BN4_10714Glycosyl transferase family 9. (416 aa)
BN4_10819Glycosyltransferase. (330 aa)
BN4_10820Glycosyl transferase group 1. (377 aa)
BN4_10824Glycosyl transferase family 2. (240 aa)
BN4_10959Glycosyl transferase group 1. (422 aa)
BN4_10978Glycosyl transferase family 2. (539 aa)
BN4_10980Glycosyl transferase family 2. (542 aa)
BN4_10981Glycosyl transferase family 2. (560 aa)
BN4_11009Homologs of previously reported genes of unknown function. (589 aa)
BN4_11041Glycosyl transferase family 39. (540 aa)
lpxBLipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (381 aa)
BN4_11057Dolichyl-phosphate-mannose-protein mannosyltransferase family protein. (545 aa)
yvgNGlyoxal reductase. (283 aa)
opgGGlucans biosynthesis protein G; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (532 aa)
opgHGlucans biosynthesis glucosyltransferase H. (706 aa)
BN4_11227Putative O-antigen acetylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (658 aa)
BN4_11355Acylneuraminate cytidylyltransferase. (238 aa)
BN4_11359Homologs of previously reported genes of unknown function. (165 aa)
BN4_11364NeuB family protein. (344 aa)
BN4_11390Glycosyl transferase family 2. (382 aa)
capLProtein CapL; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (440 aa)
BN4_11817Glycosyl transferase group 1. (424 aa)
BN4_11846Lipopolysaccharide heptosyltransferase II. (354 aa)
BN4_11922Glucose-6-phosphate isomerase. (446 aa)
BN4_11964Homologs of previously reported genes of unknown function. (439 aa)
BN4_11980Glycosyl transferase family 9. (320 aa)
BN4_12004Glycosyl transferase family 2. (539 aa)
BN4_12005Glycosyl transferase family 2. (559 aa)
BN4_12061UDP-glucose/GDP-mannose dehydrogenase. (415 aa)
BN4_12080GHMP kinase. (326 aa)
BN4_12085Acylneuraminate cytidylyltransferase (modular protein). (396 aa)
BN4_12087Homologs of previously reported genes of unknown function. (600 aa)
BN4_12125Glycosyl transferase group 1. (371 aa)
BN4_12142Glycosyl transferase family 2. (555 aa)
BN4_12227Low specificity phosphatase (HAD superfamily)-like protein. (264 aa)
BN4_12381Glycosyl transferase group 1. (385 aa)
BN4_12415Glycosyl transferase group 1. (378 aa)
yggFPutative hexoseP phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (329 aa)
glmUBifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (459 aa)
BN4_12589Glycosyl transferase family 9. (469 aa)
BN4_12645N-acylneuraminate-9-phosphate synthase. (363 aa)
otsATrehalose-phosphate synthase. (490 aa)
BN4_12664Homologs of previously reported genes of unknown function. (555 aa)
BN4_12680N-acetylneuraminate synthase. (350 aa)
BN4_12686CMP-N-acetlyneuraminic acid synthetase. (241 aa)
BN4_12687Protein of unknown function; No homology to any previously reported sequences. (512 aa)
BN4_12688Glycosyltransferase, group 1 family protein. (386 aa)
BN4_12692Glycosyl transferase group 1. (372 aa)
BN4_12694Alginate o-acetyltransferase algI; Belongs to the membrane-bound acyltransferase family. (465 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (373 aa)
BN4_12738Putative Trehalose 6-Phosphate Synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (400 aa)
BN4_12822Metallophosphoesterase. (395 aa)
BN4_20024Pyruvate, water dikinase. (863 aa)
BN4_20043Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase. (469 aa)
BN4_20047Tyrosine-protein kinase. (270 aa)
BN4_20048Lipopolysaccharide biosynthesis protein. (584 aa)
BN4_20088Pyruvate phosphate dikinase PEP/pyruvate-binding. (820 aa)
BN4_20163Homologs of previously reported genes of unknown function. (352 aa)
BN4_20183Phosphorylase. (1413 aa)
BN4_20185Glycosyl transferase group 1. (428 aa)
BN4_20341Alginate o-acetyltransferase algI; Belongs to the membrane-bound acyltransferase family. (465 aa)
BN4_20358Sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family. (219 aa)
BN4_20361Glycosyl transferase family 9. (339 aa)
BN4_20441Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (428 aa)
Your Current Organism:
Pseudodesulfovibrio piezophilus
NCBI taxonomy Id: 1322246
Other names: Desulfovibrio piezophilus C1TLV30, Desulfovibrio piezophilus DSM 21447, Desulfovibrio piezophilus JCM 15486, Desulfovibrio sp. C1TLV30, P. piezophilus C1TLV30, Pseudodesulfovibrio piezophilus C1TLV30, Pseudodesulfovibrio piezophilus DSM 21447, Pseudodesulfovibrio piezophilus JCM 15486
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