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paaK paaK paaK-2 paaK-2 yngI yngI paaK-3 paaK-3 BN4_11245 BN4_11245 acsA acsA BN4_12231 BN4_12231 acsA-2 acsA-2 yngI-2 yngI-2 BN4_20283 BN4_20283 Acsm Acsm fadD fadD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
paaKPhenylacetate-coenzyme A ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (434 aa)
paaK-2Phenylacetate-coenzyme A ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (428 aa)
yngIacyl-CoA synthetase yngI; Function of strongly homologous gene; enzyme. (604 aa)
paaK-3Phenylacetate-coenzyme A ligase; Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). (429 aa)
BN4_11245Putative AMP-binding enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (2101 aa)
acsAAcetyl-coenzyme A synthetase. (667 aa)
BN4_12231Putative Phenylacetate-coenzyme A ligase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (421 aa)
acsA-2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
yngI-2acyl-CoA synthetase yngI; Function of strongly homologous gene; enzyme. (546 aa)
BN4_20283Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family. (533 aa)
AcsmAcyl-coenzyme A synthetase ACSM4, mitochondrial; Function of strongly homologous gene; putative enzyme. (545 aa)
fadDLong-chain-fatty-acid--CoA ligase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (570 aa)
Your Current Organism:
Pseudodesulfovibrio piezophilus
NCBI taxonomy Id: 1322246
Other names: Desulfovibrio piezophilus C1TLV30, Desulfovibrio piezophilus DSM 21447, Desulfovibrio piezophilus JCM 15486, Desulfovibrio sp. C1TLV30, P. piezophilus C1TLV30, Pseudodesulfovibrio piezophilus C1TLV30, Pseudodesulfovibrio piezophilus DSM 21447, Pseudodesulfovibrio piezophilus JCM 15486
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