(77 nodes) Mixed, incl. RAB geranylgeranylation, and Vesicle tethering complex network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R4FNE8_RHOPR	Putative phosphotriesterase. (347 aa)
	R4FNZ6_RHOPR	Putative ypt/rab gtpase activating protein. (336 aa)
	R4FPT4_RHOPR	Putative rab1/ypt1 subfamily protein. (202 aa)
	R4FPV9_RHOPR	Putative small gtp binding protein rab5. (213 aa)
	R4G4D0_RHOPR	Putative gtpase rab2. (189 aa)
	R4G4K6_RHOPR	Putative rab-protein 14. (214 aa)
	R4G4K8_RHOPR	Putative gtpase. (215 aa)
	R4G4R8_RHOPR	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (332 aa)
	R4G5B4_RHOPR	Putative ras-related small gtpase. (218 aa)
	R4G5K6_RHOPR	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (442 aa)
	R4G8M2_RHOPR	Putative rab-protein 10. (200 aa)
	T1HB28_RHOPR	Uncharacterized protein. (1000 aa)
	T1HBW2_RHOPR	C2H2-type domain-containing protein. (385 aa)
	T1HCJ3_RHOPR	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (66 aa)
	T1HCJ4_RHOPR	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (556 aa)
	T1HCK6_RHOPR	Rab-GAP TBC domain-containing protein. (1132 aa)
	T1HDS3_RHOPR	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (558 aa)
	T1HG95_RHOPR	Vps16_C domain-containing protein. (77 aa)
	T1HGY8_RHOPR	Uncharacterized protein. (698 aa)
	T1HHB0_RHOPR	Oxysterol-binding protein; Belongs to the OSBP family. (416 aa)
	T1HHV1_RHOPR	Rab-GAP TBC domain-containing protein. (166 aa)
	T1HI99_RHOPR	Uncharacterized protein. (222 aa)
	T1HIY4_RHOPR	Uncharacterized protein. (144 aa)
	T1HJ83_RHOPR	Uncharacterized protein. (186 aa)
	T1HJD8_RHOPR	Vps16_C domain-containing protein. (444 aa)
	T1HJU5_RHOPR	RH1 domain-containing protein. (145 aa)
	T1HJW9_RHOPR	RH2 domain-containing protein. (169 aa)
	T1HKJ9_RHOPR	Sec2p domain-containing protein. (332 aa)
	T1HPB3_RHOPR	Uncharacterized protein. (249 aa)
	T1HQ60_RHOPR	Uncharacterized protein. (254 aa)
	T1HQV7_RHOPR	Uncharacterized protein. (173 aa)
	T1HR06_RHOPR	Uncharacterized protein. (79 aa)
	T1HR85_RHOPR	Uncharacterized protein. (871 aa)
	T1HR96_RHOPR	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (826 aa)
	T1HRM2_RHOPR	A20-type domain-containing protein. (110 aa)
	T1HS10_RHOPR	Uncharacterized protein. (199 aa)
	T1HU79_RHOPR	Uncharacterized protein. (221 aa)
	T1HUE8_RHOPR	Uncharacterized protein. (314 aa)
	T1HUG8_RHOPR	Uncharacterized protein. (167 aa)
	T1HUQ5_RHOPR	VPS9 domain-containing protein. (1472 aa)
	T1HUX1_RHOPR	Uncharacterized protein. (311 aa)
	T1HVK6_RHOPR	Pep3_Vps18 domain-containing protein. (962 aa)
	T1HVV6_RHOPR	Rab-GAP TBC domain-containing protein. (740 aa)
	T1HW94_RHOPR	Uncharacterized protein. (207 aa)
	T1HW95_RHOPR	Uncharacterized protein. (202 aa)
	T1HWH6_RHOPR	CNH domain-containing protein. (857 aa)
	T1HXA5_RHOPR	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. (522 aa)
	T1HZ53_RHOPR	Uncharacterized protein. (249 aa)
	T1HZN4_RHOPR	Uncharacterized protein. (314 aa)
	T1I0N6_RHOPR	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (890 aa)
	T1I131_RHOPR	F-box domain-containing protein. (511 aa)
	T1I1A4_RHOPR	VPS9 domain-containing protein. (632 aa)
	T1I1R3_RHOPR	FIP-RBD domain-containing protein. (278 aa)
	T1I249_RHOPR	Uncharacterized protein. (887 aa)
	T1I3P1_RHOPR	Sec8_exocyst domain-containing protein. (965 aa)
	T1I600_RHOPR	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (581 aa)
	T1I652_RHOPR	RING-type domain-containing protein. (845 aa)
	T1I6R4_RHOPR	Vps8 domain-containing protein. (965 aa)
	T1I6S3_RHOPR	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (303 aa)
	T1I6S9_RHOPR	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (394 aa)
	T1I6U3_RHOPR	PH domain-containing protein. (682 aa)
	T1I7B6_RHOPR	Exocyst complex component 1. (889 aa)
	T1I7L5_RHOPR	Uncharacterized protein. (184 aa)
	T1I7U6_RHOPR	Uncharacterized protein. (296 aa)
	T1I8Y0_RHOPR	Uncharacterized protein. (1228 aa)
	T1I8Y9_RHOPR	Uncharacterized protein. (1435 aa)
	T1I9U6_RHOPR	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1728 aa)
	T1IAQ6_RHOPR	Uncharacterized protein. (212 aa)
	T1IBN5_RHOPR	Uncharacterized protein. (306 aa)
	T1IBU7_RHOPR	Uncharacterized protein. (330 aa)
	T1IC95_RHOPR	Uncharacterized protein. (206 aa)
	T1ICC1_RHOPR	Uncharacterized protein. (762 aa)
	T1ID71_RHOPR	CABIT domain-containing protein. (579 aa)
	T1IF13_RHOPR	FIP-RBD domain-containing protein. (391 aa)
	T1IF60_RHOPR	Uncharacterized protein. (220 aa)
	T1IGL1_RHOPR	Uncharacterized protein. (76 aa)
	T1IGN4_RHOPR	Uncharacterized protein. (218 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4FNE8_RHOPR	R4FNZ6_RHOPR	R4FNE8	R4FNZ6	Putative phosphotriesterase.	Putative ypt/rab gtpase activating protein.	0.651
R4FNE8_RHOPR	R4FPT4_RHOPR	R4FNE8	R4FPT4	Putative phosphotriesterase.	Putative rab1/ypt1 subfamily protein.	0.595
R4FNE8_RHOPR	R4FPV9_RHOPR	R4FNE8	R4FPV9	Putative phosphotriesterase.	Putative small gtp binding protein rab5.	0.552
R4FNE8_RHOPR	R4G4D0_RHOPR	R4FNE8	R4G4D0	Putative phosphotriesterase.	Putative gtpase rab2.	0.470
R4FNE8_RHOPR	R4G4K6_RHOPR	R4FNE8	R4G4K6	Putative phosphotriesterase.	Putative rab-protein 14.	0.617
R4FNE8_RHOPR	R4G4K8_RHOPR	R4FNE8	R4G4K8	Putative phosphotriesterase.	Putative gtpase.	0.718
R4FNE8_RHOPR	R4G4R8_RHOPR	R4FNE8	R4G4R8	Putative phosphotriesterase.	Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.	0.746
R4FNE8_RHOPR	R4G5K6_RHOPR	R4FNE8	R4G5K6	Putative phosphotriesterase.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.885
R4FNE8_RHOPR	T1HCJ3_RHOPR	R4FNE8	T1HCJ3	Putative phosphotriesterase.	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.656
R4FNE8_RHOPR	T1HCJ4_RHOPR	R4FNE8	T1HCJ4	Putative phosphotriesterase.	Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.	0.656
R4FNE8_RHOPR	T1HG95_RHOPR	R4FNE8	T1HG95	Putative phosphotriesterase.	Vps16_C domain-containing protein.	0.462
R4FNE8_RHOPR	T1HGY8_RHOPR	R4FNE8	T1HGY8	Putative phosphotriesterase.	Uncharacterized protein.	0.723
R4FNE8_RHOPR	T1HHB0_RHOPR	R4FNE8	T1HHB0	Putative phosphotriesterase.	Oxysterol-binding protein; Belongs to the OSBP family.	0.575
R4FNE8_RHOPR	T1HHV1_RHOPR	R4FNE8	T1HHV1	Putative phosphotriesterase.	Rab-GAP TBC domain-containing protein.	0.651
R4FNE8_RHOPR	T1HI99_RHOPR	R4FNE8	T1HI99	Putative phosphotriesterase.	Uncharacterized protein.	0.637
R4FNE8_RHOPR	T1HIY4_RHOPR	R4FNE8	T1HIY4	Putative phosphotriesterase.	Uncharacterized protein.	0.595
R4FNE8_RHOPR	T1HJ83_RHOPR	R4FNE8	T1HJ83	Putative phosphotriesterase.	Uncharacterized protein.	0.470
R4FNE8_RHOPR	T1HJU5_RHOPR	R4FNE8	T1HJU5	Putative phosphotriesterase.	RH1 domain-containing protein.	0.623
R4FNE8_RHOPR	T1HJW9_RHOPR	R4FNE8	T1HJW9	Putative phosphotriesterase.	RH2 domain-containing protein.	0.692
R4FNE8_RHOPR	T1HKJ9_RHOPR	R4FNE8	T1HKJ9	Putative phosphotriesterase.	Sec2p domain-containing protein.	0.885