(5 nodes) Retromer, cargo-selective complex network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R4G544_RHOPR	Putative sorting nexin snx11. (166 aa)
	R4G562_RHOPR	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (182 aa)
	T1HBM4_RHOPR	Uncharacterized protein. (429 aa)
	T1HIG2_RHOPR	Uncharacterized protein. (371 aa)
	T1IAV5_RHOPR	Uncharacterized protein. (68 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4G544_RHOPR	R4G562_RHOPR	R4G544	R4G562	Putative sorting nexin snx11.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.910
R4G544_RHOPR	T1HBM4_RHOPR	R4G544	T1HBM4	Putative sorting nexin snx11.	Uncharacterized protein.	0.981
R4G544_RHOPR	T1HIG2_RHOPR	R4G544	T1HIG2	Putative sorting nexin snx11.	Uncharacterized protein.	0.989
R4G544_RHOPR	T1IAV5_RHOPR	R4G544	T1IAV5	Putative sorting nexin snx11.	Uncharacterized protein.	0.981
R4G562_RHOPR	R4G544_RHOPR	R4G562	R4G544	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Putative sorting nexin snx11.	0.910
R4G562_RHOPR	T1HBM4_RHOPR	R4G562	T1HBM4	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Uncharacterized protein.	0.989
R4G562_RHOPR	T1HIG2_RHOPR	R4G562	T1HIG2	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Uncharacterized protein.	0.998
R4G562_RHOPR	T1IAV5_RHOPR	R4G562	T1IAV5	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	Uncharacterized protein.	0.989
T1HBM4_RHOPR	R4G544_RHOPR	T1HBM4	R4G544	Uncharacterized protein.	Putative sorting nexin snx11.	0.981
T1HBM4_RHOPR	R4G562_RHOPR	T1HBM4	R4G562	Uncharacterized protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.989
T1HBM4_RHOPR	T1HIG2_RHOPR	T1HBM4	T1HIG2	Uncharacterized protein.	Uncharacterized protein.	0.991
T1HBM4_RHOPR	T1IAV5_RHOPR	T1HBM4	T1IAV5	Uncharacterized protein.	Uncharacterized protein.	0.592
T1HIG2_RHOPR	R4G544_RHOPR	T1HIG2	R4G544	Uncharacterized protein.	Putative sorting nexin snx11.	0.989
T1HIG2_RHOPR	R4G562_RHOPR	T1HIG2	R4G562	Uncharacterized protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.998
T1HIG2_RHOPR	T1HBM4_RHOPR	T1HIG2	T1HBM4	Uncharacterized protein.	Uncharacterized protein.	0.991
T1HIG2_RHOPR	T1IAV5_RHOPR	T1HIG2	T1IAV5	Uncharacterized protein.	Uncharacterized protein.	0.991
T1IAV5_RHOPR	R4G544_RHOPR	T1IAV5	R4G544	Uncharacterized protein.	Putative sorting nexin snx11.	0.981
T1IAV5_RHOPR	R4G562_RHOPR	T1IAV5	R4G562	Uncharacterized protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.989
T1IAV5_RHOPR	T1HBM4_RHOPR	T1IAV5	T1HBM4	Uncharacterized protein.	Uncharacterized protein.	0.592
T1IAV5_RHOPR	T1HIG2_RHOPR	T1IAV5	T1HIG2	Uncharacterized protein.	Uncharacterized protein.	0.991