(102 nodes) Mixed, incl. Small GTPase mediated signal transduction, and Transmembrane receptor protein tyrosine kinase signaling pathway network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R4FN11_RHOPR	Putative ras-related small gtpase. (191 aa)
	R4FQA8_RHOPR	Putative actin length. (376 aa)
	R4G3I3_RHOPR	Putative rts beta protein. (415 aa)
	R4G4N6_RHOPR	Putative ras-like gtp-binding protein rhoa. (187 aa)
	R4G508_RHOPR	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
	R4G578_RHOPR	Putative ras-related protein rac1 isoform 1. (192 aa)
	R4G584_RHOPR	Putative muscle ras oncoprotein. (197 aa)
	R4G8L9_RHOPR	Putative ras-like gtp-binding protein rho1 isoform 1. (193 aa)
	R4G8M1_RHOPR	Uncharacterized protein. (199 aa)
	T1H7T3_RHOPR	Uncharacterized protein. (236 aa)
	T1H8W8_RHOPR	SH3 domain-containing protein. (105 aa)
	T1H974_RHOPR	Tyrosine-protein kinase receptor. (1293 aa)
	T1H9W6_RHOPR	Uncharacterized protein. (495 aa)
	T1HA22_RHOPR	Uncharacterized protein. (547 aa)
	T1HAD7_RHOPR	Uncharacterized protein. (589 aa)
	T1HAL7_RHOPR	Uncharacterized protein. (697 aa)
	T1HAL8_RHOPR	PH domain-containing protein. (94 aa)
	T1HB09_RHOPR	Uncharacterized protein. (166 aa)
	T1HB35_RHOPR	Tyrosine-protein kinase receptor. (2263 aa)
	T1HBM8_RHOPR	Uncharacterized protein. (128 aa)
	T1HCF6_RHOPR	Uncharacterized protein. (1156 aa)
	T1HCL0_RHOPR	Rho-GAP domain-containing protein. (578 aa)
	T1HD54_RHOPR	Ras-GEF domain-containing protein. (424 aa)
	T1HD99_RHOPR	Uncharacterized protein. (486 aa)
	T1HG20_RHOPR	LIM zinc-binding domain-containing protein. (91 aa)
	T1HHE8_RHOPR	LIM zinc-binding domain-containing protein. (157 aa)
	T1HIN4_RHOPR	Uncharacterized protein. (2441 aa)
	T1HJB2_RHOPR	VASP_tetra domain-containing protein. (178 aa)
	T1HKB0_RHOPR	Uncharacterized protein. (771 aa)
	T1HKY3_RHOPR	Uncharacterized protein. (917 aa)
	T1HLQ2_RHOPR	Uncharacterized protein. (411 aa)
	T1HLX7_RHOPR	Uncharacterized protein. (227 aa)
	T1HM61_RHOPR	Uncharacterized protein. (241 aa)
	T1HN03_RHOPR	Ig-like domain-containing protein. (235 aa)
	T1HN67_RHOPR	Non-specific serine/threonine protein kinase. (654 aa)
	T1HN74_RHOPR	Uncharacterized protein. (201 aa)
	T1HNF8_RHOPR	Uncharacterized protein; Belongs to the DOCK family. (1925 aa)
	T1HP78_RHOPR	Uncharacterized protein. (189 aa)
	T1HQH8_RHOPR	Uncharacterized protein. (781 aa)
	T1HQL8_RHOPR	PH domain-containing protein. (123 aa)
	T1HQP7_RHOPR	Uncharacterized protein. (697 aa)
	T1HQQ7_RHOPR	Uncharacterized protein. (957 aa)
	T1HQT4_RHOPR	N-terminal Ras-GEF domain-containing protein. (306 aa)
	T1HQX9_RHOPR	Uncharacterized protein. (187 aa)
	T1HRW0_RHOPR	Uncharacterized protein. (274 aa)
	T1HS66_RHOPR	Uncharacterized protein. (202 aa)
	T1HSP6_RHOPR	Uncharacterized protein. (185 aa)
	T1HSY1_RHOPR	Uncharacterized protein. (1078 aa)
	T1HSZ9_RHOPR	Uncharacterized protein. (219 aa)
	T1HTF3_RHOPR	Rho-GAP domain-containing protein. (288 aa)
	T1HTR5_RHOPR	Uncharacterized protein. (2570 aa)
	T1HUC4_RHOPR	Uncharacterized protein. (193 aa)
	T1HUL2_RHOPR	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1334 aa)
	T1HV34_RHOPR	PLCXc domain-containing protein. (132 aa)
	T1HV52_RHOPR	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2088 aa)
	T1HVI6_RHOPR	Uncharacterized protein. (241 aa)
	T1HVL0_RHOPR	Uncharacterized protein. (1165 aa)
	T1HWB6_RHOPR	Tyrosine-protein kinase. (534 aa)
	T1HWF6_RHOPR	Uncharacterized protein. (145 aa)
	T1HWM7_RHOPR	PH domain-containing protein. (72 aa)
	T1HX06_RHOPR	Uncharacterized protein. (748 aa)
	T1HXD2_RHOPR	Uncharacterized protein. (88 aa)
	T1HXT3_RHOPR	Uncharacterized protein. (116 aa)
	T1HXT4_RHOPR	Uncharacterized protein. (60 aa)
	T1HZ23_RHOPR	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1055 aa)
	T1HZG1_RHOPR	Pkinase_Tyr domain-containing protein. (135 aa)
	T1HZG9_RHOPR	Uncharacterized protein. (696 aa)
	T1HZL6_RHOPR	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1729 aa)
	T1I0P2_RHOPR	Uncharacterized protein. (262 aa)
	T1I1G4_RHOPR	Tyrosine-protein kinase. (501 aa)
	T1I2D8_RHOPR	SH3 domain-containing protein. (509 aa)
	T1I2J6_RHOPR	Integrin beta. (582 aa)
	T1I2Z0_RHOPR	Integrin beta. (211 aa)
	T1I376_RHOPR	Uncharacterized protein. (776 aa)
	T1I3P4_RHOPR	BTB domain-containing protein. (712 aa)
	T1I3W9_RHOPR	WH1 domain-containing protein. (788 aa)
	T1I409_RHOPR	Uncharacterized protein. (380 aa)
	T1I4F0_RHOPR	Uncharacterized protein. (1230 aa)
	T1I4G8_RHOPR	ELMO domain-containing protein. (730 aa)
	T1I4J2_RHOPR	Non-specific serine/threonine protein kinase. (515 aa)
	T1I5Y1_RHOPR	Rho-GAP domain-containing protein. (159 aa)
	T1I5Y3_RHOPR	Uncharacterized protein. (162 aa)
	T1I5Y5_RHOPR	Uncharacterized protein. (414 aa)
	T1I6D8_RHOPR	Uncharacterized protein. (1130 aa)
	T1I6Z7_RHOPR	Uncharacterized protein; Belongs to the DOCK family. (1602 aa)
	T1I839_RHOPR	Uncharacterized protein. (113 aa)
	T1I867_RHOPR	Tyrosine-protein kinase Fak56D. (1228 aa)
	T1I933_RHOPR	C2 tensin-type domain-containing protein. (148 aa)
	T1I935_RHOPR	C2 tensin-type domain-containing protein. (99 aa)
	T1I937_RHOPR	Phosphatase tensin-type domain-containing protein. (230 aa)
	T1I9G2_RHOPR	Tyrosine-protein kinase Csk; Belongs to the protein kinase superfamily. Tyr protein kinase family. (261 aa)
	T1IA40_RHOPR	Uncharacterized protein. (164 aa)
	T1IAV0_RHOPR	Uncharacterized protein. (1663 aa)
	T1IB37_RHOPR	Uncharacterized protein. (181 aa)
	T1IBQ7_RHOPR	Uncharacterized protein. (1041 aa)
	T1IC23_RHOPR	Uncharacterized protein. (435 aa)
	T1ICJ0_RHOPR	Uncharacterized protein. (432 aa)
	T1ID89_RHOPR	Uncharacterized protein. (1702 aa)
	T1IDP0_RHOPR	Uncharacterized protein. (478 aa)
	T1IE91_RHOPR	Uncharacterized protein. (835 aa)
	T1IEJ6_RHOPR	Uncharacterized protein. (262 aa)
	T1IFY1_RHOPR	Uncharacterized protein. (1534 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4FN11_RHOPR	R4FQA8_RHOPR	R4FN11	R4FQA8	Putative ras-related small gtpase.	Putative actin length.	0.582
R4FN11_RHOPR	R4G3I3_RHOPR	R4FN11	R4G3I3	Putative ras-related small gtpase.	Putative rts beta protein.	0.640
R4FN11_RHOPR	R4G4N6_RHOPR	R4FN11	R4G4N6	Putative ras-related small gtpase.	Putative ras-like gtp-binding protein rhoa.	0.683
R4FN11_RHOPR	R4G508_RHOPR	R4FN11	R4G508	Putative ras-related small gtpase.	Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.	0.711
R4FN11_RHOPR	R4G584_RHOPR	R4FN11	R4G584	Putative ras-related small gtpase.	Putative muscle ras oncoprotein.	0.436
R4FN11_RHOPR	R4G8L9_RHOPR	R4FN11	R4G8L9	Putative ras-related small gtpase.	Putative ras-like gtp-binding protein rho1 isoform 1.	0.677
R4FN11_RHOPR	R4G8M1_RHOPR	R4FN11	R4G8M1	Putative ras-related small gtpase.	Uncharacterized protein.	0.732
R4FN11_RHOPR	T1H8W8_RHOPR	R4FN11	T1H8W8	Putative ras-related small gtpase.	SH3 domain-containing protein.	0.960
R4FN11_RHOPR	T1H974_RHOPR	R4FN11	T1H974	Putative ras-related small gtpase.	Tyrosine-protein kinase receptor.	0.579
R4FN11_RHOPR	T1H9W6_RHOPR	R4FN11	T1H9W6	Putative ras-related small gtpase.	Uncharacterized protein.	0.649
R4FN11_RHOPR	T1HA22_RHOPR	R4FN11	T1HA22	Putative ras-related small gtpase.	Uncharacterized protein.	0.960
R4FN11_RHOPR	T1HAD7_RHOPR	R4FN11	T1HAD7	Putative ras-related small gtpase.	Uncharacterized protein.	0.771
R4FN11_RHOPR	T1HAL7_RHOPR	R4FN11	T1HAL7	Putative ras-related small gtpase.	Uncharacterized protein.	0.705
R4FN11_RHOPR	T1HAL8_RHOPR	R4FN11	T1HAL8	Putative ras-related small gtpase.	PH domain-containing protein.	0.705
R4FN11_RHOPR	T1HB09_RHOPR	R4FN11	T1HB09	Putative ras-related small gtpase.	Uncharacterized protein.	0.695
R4FN11_RHOPR	T1HB35_RHOPR	R4FN11	T1HB35	Putative ras-related small gtpase.	Tyrosine-protein kinase receptor.	0.579
R4FN11_RHOPR	T1HCL0_RHOPR	R4FN11	T1HCL0	Putative ras-related small gtpase.	Rho-GAP domain-containing protein.	0.620
R4FN11_RHOPR	T1HD54_RHOPR	R4FN11	T1HD54	Putative ras-related small gtpase.	Ras-GEF domain-containing protein.	0.649
R4FN11_RHOPR	T1HG20_RHOPR	R4FN11	T1HG20	Putative ras-related small gtpase.	LIM zinc-binding domain-containing protein.	0.732
R4FN11_RHOPR	T1HHE8_RHOPR	R4FN11	T1HHE8	Putative ras-related small gtpase.	LIM zinc-binding domain-containing protein.	0.522