(29 nodes) Mixed, incl. Small GTPase Rho, and NRAGE signals death through JNK network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R4G578_RHOPR	Putative ras-related protein rac1 isoform 1. (192 aa)
	R4G8L9_RHOPR	Putative ras-like gtp-binding protein rho1 isoform 1. (193 aa)
	T1H8W8_RHOPR	SH3 domain-containing protein. (105 aa)
	T1HA22_RHOPR	Uncharacterized protein. (547 aa)
	T1HAD7_RHOPR	Uncharacterized protein. (589 aa)
	T1HAL7_RHOPR	Uncharacterized protein. (697 aa)
	T1HAL8_RHOPR	PH domain-containing protein. (94 aa)
	T1HBM8_RHOPR	Uncharacterized protein. (128 aa)
	T1HIN4_RHOPR	Uncharacterized protein. (2441 aa)
	T1HLQ2_RHOPR	Uncharacterized protein. (411 aa)
	T1HLX7_RHOPR	Uncharacterized protein. (227 aa)
	T1HN67_RHOPR	Non-specific serine/threonine protein kinase. (654 aa)
	T1HNF8_RHOPR	Uncharacterized protein; Belongs to the DOCK family. (1925 aa)
	T1HP78_RHOPR	Uncharacterized protein. (189 aa)
	T1HQP7_RHOPR	Uncharacterized protein. (697 aa)
	T1HQQ7_RHOPR	Uncharacterized protein. (957 aa)
	T1HSP6_RHOPR	Uncharacterized protein. (185 aa)
	T1HUC4_RHOPR	Uncharacterized protein. (193 aa)
	T1HUL2_RHOPR	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1334 aa)
	T1HV52_RHOPR	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2088 aa)
	T1HXT3_RHOPR	Uncharacterized protein. (116 aa)
	T1HXT4_RHOPR	Uncharacterized protein. (60 aa)
	T1I3P4_RHOPR	BTB domain-containing protein. (712 aa)
	T1I3W9_RHOPR	WH1 domain-containing protein. (788 aa)
	T1I4G8_RHOPR	ELMO domain-containing protein. (730 aa)
	T1I4J2_RHOPR	Non-specific serine/threonine protein kinase. (515 aa)
	T1I6Z7_RHOPR	Uncharacterized protein; Belongs to the DOCK family. (1602 aa)
	T1IE91_RHOPR	Uncharacterized protein. (835 aa)
	T1IFY1_RHOPR	Uncharacterized protein. (1534 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4G578_RHOPR	R4G8L9_RHOPR	R4G578	R4G8L9	Putative ras-related protein rac1 isoform 1.	Putative ras-like gtp-binding protein rho1 isoform 1.	0.678
R4G578_RHOPR	T1H8W8_RHOPR	R4G578	T1H8W8	Putative ras-related protein rac1 isoform 1.	SH3 domain-containing protein.	0.960
R4G578_RHOPR	T1HA22_RHOPR	R4G578	T1HA22	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein.	0.960
R4G578_RHOPR	T1HAD7_RHOPR	R4G578	T1HAD7	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein.	0.771
R4G578_RHOPR	T1HAL7_RHOPR	R4G578	T1HAL7	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein.	0.705
R4G578_RHOPR	T1HAL8_RHOPR	R4G578	T1HAL8	Putative ras-related protein rac1 isoform 1.	PH domain-containing protein.	0.705
R4G578_RHOPR	T1HIN4_RHOPR	R4G578	T1HIN4	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein.	0.964
R4G578_RHOPR	T1HLQ2_RHOPR	R4G578	T1HLQ2	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein.	0.752
R4G578_RHOPR	T1HLX7_RHOPR	R4G578	T1HLX7	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein.	0.663
R4G578_RHOPR	T1HN67_RHOPR	R4G578	T1HN67	Putative ras-related protein rac1 isoform 1.	Non-specific serine/threonine protein kinase.	0.946
R4G578_RHOPR	T1HNF8_RHOPR	R4G578	T1HNF8	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein; Belongs to the DOCK family.	0.889
R4G578_RHOPR	T1HP78_RHOPR	R4G578	T1HP78	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein.	0.929
R4G578_RHOPR	T1HQP7_RHOPR	R4G578	T1HQP7	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein.	0.960
R4G578_RHOPR	T1HQQ7_RHOPR	R4G578	T1HQQ7	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein.	0.960
R4G578_RHOPR	T1HUC4_RHOPR	R4G578	T1HUC4	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein.	0.679
R4G578_RHOPR	T1HUL2_RHOPR	R4G578	T1HUL2	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.684
R4G578_RHOPR	T1HV52_RHOPR	R4G578	T1HV52	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.969
R4G578_RHOPR	T1HXT3_RHOPR	R4G578	T1HXT3	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein.	0.895
R4G578_RHOPR	T1HXT4_RHOPR	R4G578	T1HXT4	Putative ras-related protein rac1 isoform 1.	Uncharacterized protein.	0.896
R4G578_RHOPR	T1I3W9_RHOPR	R4G578	T1I3W9	Putative ras-related protein rac1 isoform 1.	WH1 domain-containing protein.	0.705