(39 nodes) Mixed, incl. Apoptosis - multiple species, and Regulation of I-kappaB kinase/NF-kappaB signaling network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R4FMU0_RHOPR	Putative ubiquitin-like protein. (135 aa)
	R4G3N8_RHOPR	Putative ubiquitin-like 7 bone marrow stromal cell-derived. (358 aa)
	R4G4E7_RHOPR	Putative cuticle protein. (152 aa)
	R4G8I1_RHOPR	Putative cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (108 aa)
	T1H8Q6_RHOPR	Protein kinase domain-containing protein. (755 aa)
	T1HCP5_RHOPR	RING-type domain-containing protein. (373 aa)
	T1HD15_RHOPR	ANK_REP_REGION domain-containing protein. (52 aa)
	T1HDI4_RHOPR	Uncharacterized protein. (1128 aa)
	T1HEF7_RHOPR	Uncharacterized protein. (227 aa)
	T1HFT9_RHOPR	Ubiquilin. (543 aa)
	T1HH56_RHOPR	RING-type domain-containing protein. (258 aa)
	T1HIS3_RHOPR	Uncharacterized protein; Belongs to the peptidase C14A family. (257 aa)
	T1HJ81_RHOPR	TIR domain-containing protein; Belongs to the Toll-like receptor family. (1238 aa)
	T1HNA7_RHOPR	PPM-type phosphatase domain-containing protein. (462 aa)
	T1HNR1_RHOPR	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (477 aa)
	T1HP97_RHOPR	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (404 aa)
	T1HRA7_RHOPR	Uncharacterized protein. (400 aa)
	T1HRR6_RHOPR	Uncharacterized protein. (378 aa)
	T1HSP8_RHOPR	RING-type domain-containing protein. (524 aa)
	T1HT25_RHOPR	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (254 aa)
	T1HUN5_RHOPR	RING-type domain-containing protein. (313 aa)
	T1HZK8_RHOPR	ANK_REP_REGION domain-containing protein. (200 aa)
	T1HZL0_RHOPR	MIB/HERC2 domain-containing protein. (347 aa)
	T1I0G4_RHOPR	Uncharacterized protein. (128 aa)
	T1I0G5_RHOPR	Uncharacterized protein. (171 aa)
	T1I2Q9_RHOPR	Uncharacterized protein. (257 aa)
	T1I2U5_RHOPR	Uncharacterized protein. (254 aa)
	T1I2Y3_RHOPR	Thioredoxin domain-containing protein. (503 aa)
	T1I393_RHOPR	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. (289 aa)
	T1I4B0_RHOPR	Uncharacterized protein; Belongs to the peptidase C14A family. (427 aa)
	T1I692_RHOPR	Uncharacterized protein. (386 aa)
	T1I6D9_RHOPR	Uncharacterized protein. (213 aa)
	T1IB16_RHOPR	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (401 aa)
	T1IC45_RHOPR	Uncharacterized protein. (123 aa)
	T1ICP6_RHOPR	USP domain-containing protein. (336 aa)
	T1ID21_RHOPR	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (191 aa)
	T1ID44_RHOPR	Protein kinase domain-containing protein. (241 aa)
	T1IEE5_RHOPR	USP domain-containing protein. (265 aa)
	T1IEN4_RHOPR	DUF4203 domain-containing protein. (250 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4FMU0_RHOPR	R4G3N8_RHOPR	R4FMU0	R4G3N8	Putative ubiquitin-like protein.	Putative ubiquitin-like 7 bone marrow stromal cell-derived.	0.964
R4FMU0_RHOPR	T1H8Q6_RHOPR	R4FMU0	T1H8Q6	Putative ubiquitin-like protein.	Protein kinase domain-containing protein.	0.578
R4FMU0_RHOPR	T1HCP5_RHOPR	R4FMU0	T1HCP5	Putative ubiquitin-like protein.	RING-type domain-containing protein.	0.749
R4FMU0_RHOPR	T1HD15_RHOPR	R4FMU0	T1HD15	Putative ubiquitin-like protein.	ANK_REP_REGION domain-containing protein.	0.973
R4FMU0_RHOPR	T1HDI4_RHOPR	R4FMU0	T1HDI4	Putative ubiquitin-like protein.	Uncharacterized protein.	0.637
R4FMU0_RHOPR	T1HFT9_RHOPR	R4FMU0	T1HFT9	Putative ubiquitin-like protein.	Ubiquilin.	0.959
R4FMU0_RHOPR	T1HH56_RHOPR	R4FMU0	T1HH56	Putative ubiquitin-like protein.	RING-type domain-containing protein.	0.973
R4FMU0_RHOPR	T1HIS3_RHOPR	R4FMU0	T1HIS3	Putative ubiquitin-like protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.569
R4FMU0_RHOPR	T1HNA7_RHOPR	R4FMU0	T1HNA7	Putative ubiquitin-like protein.	PPM-type phosphatase domain-containing protein.	0.545
R4FMU0_RHOPR	T1HNR1_RHOPR	R4FMU0	T1HNR1	Putative ubiquitin-like protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.578
R4FMU0_RHOPR	T1HP97_RHOPR	R4FMU0	T1HP97	Putative ubiquitin-like protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.578
R4FMU0_RHOPR	T1HRA7_RHOPR	R4FMU0	T1HRA7	Putative ubiquitin-like protein.	Uncharacterized protein.	0.881
R4FMU0_RHOPR	T1HRR6_RHOPR	R4FMU0	T1HRR6	Putative ubiquitin-like protein.	Uncharacterized protein.	0.881
R4FMU0_RHOPR	T1HSP8_RHOPR	R4FMU0	T1HSP8	Putative ubiquitin-like protein.	RING-type domain-containing protein.	0.749
R4FMU0_RHOPR	T1HT25_RHOPR	R4FMU0	T1HT25	Putative ubiquitin-like protein.	CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family.	0.826
R4FMU0_RHOPR	T1HUN5_RHOPR	R4FMU0	T1HUN5	Putative ubiquitin-like protein.	RING-type domain-containing protein.	0.889
R4FMU0_RHOPR	T1HZK8_RHOPR	R4FMU0	T1HZK8	Putative ubiquitin-like protein.	ANK_REP_REGION domain-containing protein.	0.973
R4FMU0_RHOPR	T1HZL0_RHOPR	R4FMU0	T1HZL0	Putative ubiquitin-like protein.	MIB/HERC2 domain-containing protein.	0.973
R4FMU0_RHOPR	T1I0G4_RHOPR	R4FMU0	T1I0G4	Putative ubiquitin-like protein.	Uncharacterized protein.	0.806
R4FMU0_RHOPR	T1I0G5_RHOPR	R4FMU0	T1I0G5	Putative ubiquitin-like protein.	Uncharacterized protein.	0.806