(57 nodes) Spliceosomal snRNP complex, and Spliceosome network (Rhodnius prolixus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

gene neighborhood

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Your Input:
	R4FL51_RHOPR	Putative rrm rna recognition motif protein. (124 aa)
	R4FLT5_RHOPR	Putative small nuclear ribonucleoprotein snrnp smf; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (91 aa)
	R4FMF7_RHOPR	Putative rna-binding region rnp1. (462 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (88 aa)
	LSM5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (92 aa)
	R4FMR2_RHOPR	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
	R4FN48_RHOPR	Small nuclear ribonucleoprotein-associated protein. (208 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
	R4FPZ8_RHOPR	Putative u1 small nuclear ribonucleoprotein a. (234 aa)
	R4G2Z0_RHOPR	Putative u1 snrnp component. (150 aa)
	R4G311_RHOPR	Uncharacterized protein. (126 aa)
	R4G3G1_RHOPR	Putative small nuclear ribonucleoprotein smd1. (141 aa)
	R4G3L6_RHOPR	Small nuclear ribonucleoprotein Sm D3. (135 aa)
	R4G3Y9_RHOPR	Putative small nuclear ribonucleoprotein splicing factor. (111 aa)
	R4G4B5_RHOPR	Putative splicing factor sc35. (123 aa)
	R4G4V5_RHOPR	Putative u4/u6 small nuclear ribonucleoprotein prp4. (519 aa)
	R4G8I5_RHOPR	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (122 aa)
	R4G8K3_RHOPR	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family. (157 aa)
	T1H993_RHOPR	Uncharacterized protein. (1453 aa)
	T1HAI8_RHOPR	Ubiquitin-like domain-containing protein. (458 aa)
	T1HAU6_RHOPR	Melanotransferrin. (635 aa)
	T1HB81_RHOPR	Sm domain-containing protein. (65 aa)
	T1HC28_RHOPR	Uncharacterized protein. (311 aa)
	T1HHT0_RHOPR	Uncharacterized protein. (972 aa)
	T1HJP8_RHOPR	Small nuclear ribonucleoprotein G. (76 aa)
	T1HJQ1_RHOPR	Uncharacterized protein. (111 aa)
	T1HKQ2_RHOPR	Uncharacterized protein. (345 aa)
	T1HL43_RHOPR	MPN domain-containing protein. (592 aa)
	T1HL48_RHOPR	U6-snRNA_bdg domain-containing protein. (117 aa)
	T1HLL0_RHOPR	Uncharacterized protein. (2138 aa)
	T1HNN2_RHOPR	U1 small nuclear ribonucleoprotein 70K. (388 aa)
	T1HPC2_RHOPR	Uncharacterized protein. (220 aa)
	T1HR92_RHOPR	RRM domain-containing protein. (216 aa)
	T1HRH9_RHOPR	Sm domain-containing protein. (77 aa)
	T1HSG7_RHOPR	Uncharacterized protein. (229 aa)
	T1HSQ6_RHOPR	Small nuclear ribonucleoprotein Sm D2. (120 aa)
	T1HU05_RHOPR	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (184 aa)
	T1HUF0_RHOPR	Nop domain-containing protein. (488 aa)
	T1HV23_RHOPR	CPSF_A domain-containing protein. (1208 aa)
	T1HY83_RHOPR	Tr-type G domain-containing protein. (771 aa)
	T1HYR4_RHOPR	WD_REPEATS_REGION domain-containing protein. (333 aa)
	T1I0M2_RHOPR	Uncharacterized protein; Belongs to the DEAD box helicase family. (740 aa)
	T1I1M9_RHOPR	Uncharacterized protein. (660 aa)
	T1I2I1_RHOPR	PSP domain-containing protein. (861 aa)
	T1I2N4_RHOPR	TOG domain-containing protein. (1292 aa)
	T1I2N6_RHOPR	Uncharacterized protein. (349 aa)
	T1I3R8_RHOPR	Matrin-type domain-containing protein. (501 aa)
	T1I4A4_RHOPR	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (85 aa)
	T1I4W8_RHOPR	Uncharacterized protein. (271 aa)
	T1I5T8_RHOPR	Uncharacterized protein. (962 aa)
	T1I619_RHOPR	WD_REPEATS_REGION domain-containing protein. (446 aa)
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
	T1I7P3_RHOPR	Matrin-type domain-containing protein. (269 aa)
	T1I7P6_RHOPR	TPR_REGION domain-containing protein. (929 aa)
	T1I7W0_RHOPR	Uncharacterized protein. (176 aa)
	T1IDT6_RHOPR	Small nuclear ribonucleoprotein Sm D3. (151 aa)
	T1IGG7_RHOPR	C3H1-type domain-containing protein. (162 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM3	LSM4	R4FPC9	T1I6P8	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.999
LSM3	LSM5	R4FPC9	R4FMK2	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	0.999
LSM3	LSM8	R4FPC9	R4FMI7	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.999
LSM3	R4FL51_RHOPR	R4FPC9	R4FL51	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Putative rrm rna recognition motif protein.	0.684
LSM3	R4FLT5_RHOPR	R4FPC9	R4FLT5	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Putative small nuclear ribonucleoprotein snrnp smf; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.994
LSM3	R4FMF7_RHOPR	R4FPC9	R4FMF7	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Putative rna-binding region rnp1.	0.918
LSM3	R4FMR2_RHOPR	R4FPC9	R4FMR2	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.	0.977
LSM3	R4FN48_RHOPR	R4FPC9	R4FN48	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein-associated protein.	0.988
LSM3	R4FPZ8_RHOPR	R4FPC9	R4FPZ8	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Putative u1 small nuclear ribonucleoprotein a.	0.948
LSM3	R4G2Z0_RHOPR	R4FPC9	R4G2Z0	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Putative u1 snrnp component.	0.935
LSM3	R4G311_RHOPR	R4FPC9	R4G311	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.923
LSM3	R4G3G1_RHOPR	R4FPC9	R4G3G1	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Putative small nuclear ribonucleoprotein smd1.	0.973
LSM3	R4G3L6_RHOPR	R4FPC9	R4G3L6	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D3.	0.979
LSM3	R4G3Y9_RHOPR	R4FPC9	R4G3Y9	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Putative small nuclear ribonucleoprotein splicing factor.	0.999
LSM3	R4G4B5_RHOPR	R4FPC9	R4G4B5	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Putative splicing factor sc35.	0.684
LSM3	R4G4V5_RHOPR	R4FPC9	R4G4V5	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Putative u4/u6 small nuclear ribonucleoprotein prp4.	0.987
LSM3	R4G8I5_RHOPR	R4FPC9	R4G8I5	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.991
LSM3	R4G8K3_RHOPR	R4FPC9	R4G8K3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.	0.692
LSM3	T1H993_RHOPR	R4FPC9	T1H993	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.937
LSM3	T1HAI8_RHOPR	R4FPC9	T1HAI8	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Ubiquitin-like domain-containing protein.	0.929