(18 nodes) Endoplasmic reticulum unfolded protein response network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1H806_RHOPR	ARTD15_N domain-containing protein. (452 aa)
	T1HL51_RHOPR	Protein kinase domain-containing protein. (960 aa)
	T1HNP2_RHOPR	PP1c_bdg domain-containing protein. (390 aa)
	T1HQE5_RHOPR	Cyclic AMP-responsive element binding protein. (257 aa)
	T1HQI5_RHOPR	Uncharacterized protein. (64 aa)
	T1HQU4_RHOPR	BZIP domain-containing protein. (243 aa)
	T1HW70_RHOPR	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (716 aa)
	T1HXU1_RHOPR	Uncharacterized protein. (821 aa)
	T1HZ06_RHOPR	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (700 aa)
	T1I3F1_RHOPR	Uncharacterized protein. (145 aa)
	T1I603_RHOPR	Uncharacterized protein. (90 aa)
	T1I6M7_RHOPR	Uncharacterized protein. (495 aa)
	T1I9F3_RHOPR	Uncharacterized protein. (842 aa)
	T1ICK1_RHOPR	Uncharacterized protein. (722 aa)
	R4FQG8_RHOPR	Putative hsp70 protein; Belongs to the heat shock protein 70 family. (652 aa)
	R4G3I1_RHOPR	Putative transducin beta-like 2. (458 aa)
	R4G8D3_RHOPR	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (244 aa)
	T1H8D2_RHOPR	Ubiquitin-like domain-containing protein. (167 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4FQG8_RHOPR	R4G8D3_RHOPR	R4FQG8	R4G8D3	Putative hsp70 protein; Belongs to the heat shock protein 70 family.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.964
R4FQG8_RHOPR	T1HL51_RHOPR	R4FQG8	T1HL51	Putative hsp70 protein; Belongs to the heat shock protein 70 family.	Protein kinase domain-containing protein.	0.987
R4FQG8_RHOPR	T1HQU4_RHOPR	R4FQG8	T1HQU4	Putative hsp70 protein; Belongs to the heat shock protein 70 family.	BZIP domain-containing protein.	0.720
R4FQG8_RHOPR	T1HW70_RHOPR	R4FQG8	T1HW70	Putative hsp70 protein; Belongs to the heat shock protein 70 family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.410
R4FQG8_RHOPR	T1HXU1_RHOPR	R4FQG8	T1HXU1	Putative hsp70 protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.991
R4FQG8_RHOPR	T1HZ06_RHOPR	R4FQG8	T1HZ06	Putative hsp70 protein; Belongs to the heat shock protein 70 family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.613
R4FQG8_RHOPR	T1I603_RHOPR	R4FQG8	T1I603	Putative hsp70 protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.850
R4FQG8_RHOPR	T1I6M7_RHOPR	R4FQG8	T1I6M7	Putative hsp70 protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.880
R4FQG8_RHOPR	T1ICK1_RHOPR	R4FQG8	T1ICK1	Putative hsp70 protein; Belongs to the heat shock protein 70 family.	Uncharacterized protein.	0.994
R4G8D3_RHOPR	R4FQG8_RHOPR	R4G8D3	R4FQG8	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Putative hsp70 protein; Belongs to the heat shock protein 70 family.	0.964
R4G8D3_RHOPR	T1H8D2_RHOPR	R4G8D3	T1H8D2	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Ubiquitin-like domain-containing protein.	0.426
R4G8D3_RHOPR	T1HQU4_RHOPR	R4G8D3	T1HQU4	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	BZIP domain-containing protein.	0.426
R4G8D3_RHOPR	T1HXU1_RHOPR	R4G8D3	T1HXU1	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.587
R4G8D3_RHOPR	T1HZ06_RHOPR	R4G8D3	T1HZ06	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.625
R4G8D3_RHOPR	T1I603_RHOPR	R4G8D3	T1I603	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.996
R4G8D3_RHOPR	T1I6M7_RHOPR	R4G8D3	T1I6M7	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	Uncharacterized protein.	0.995
T1H8D2_RHOPR	R4G8D3_RHOPR	T1H8D2	R4G8D3	Ubiquitin-like domain-containing protein.	Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family.	0.426
T1H8D2_RHOPR	T1HZ06_RHOPR	T1H8D2	T1HZ06	Ubiquitin-like domain-containing protein.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.532
T1H8D2_RHOPR	T1I603_RHOPR	T1H8D2	T1I603	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.745
T1HL51_RHOPR	R4FQG8_RHOPR	T1HL51	R4FQG8	Protein kinase domain-containing protein.	Putative hsp70 protein; Belongs to the heat shock protein 70 family.	0.987