(31 nodes) Integral component of mitochondrial inner membrane network (Rhodnius prolixus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R4FLQ6_RHOPR	Uncharacterized protein. (79 aa)
	R4FLU8_RHOPR	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (130 aa)
	R4FP18_RHOPR	Putative mitochondrial carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (356 aa)
	R4G424_RHOPR	Uncharacterized protein. (187 aa)
	R4G4S2_RHOPR	Sidoreflexin. (325 aa)
	R4G7Y3_RHOPR	Putative mitochondrial import inner membrane translocase subunit tim23. (196 aa)
	T1H8J7_RHOPR	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (321 aa)
	T1HAC4_RHOPR	Uncharacterized protein. (270 aa)
	T1HAN2_RHOPR	MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (131 aa)
	T1HAR5_RHOPR	MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (662 aa)
	T1HC11_RHOPR	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (63 aa)
	coq2	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (356 aa)
	T1HD83_RHOPR	Uncharacterized protein. (1563 aa)
	T1HDA4_RHOPR	Sidoreflexin. (306 aa)
	T1HDG4_RHOPR	Coiled-coil_56 domain-containing protein. (88 aa)
	T1HF19_RHOPR	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (606 aa)
	T1HM68_RHOPR	MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (80 aa)
	T1HPN7_RHOPR	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (114 aa)
	T1HQP3_RHOPR	Uncharacterized protein. (215 aa)
	T1HR87_RHOPR	AAA domain-containing protein. (726 aa)
	T1HX17_RHOPR	AAA domain-containing protein; Belongs to the AAA ATPase family. (583 aa)
	T1HXP9_RHOPR	Uncharacterized protein. (49 aa)
	T1HXQ7_RHOPR	Uncharacterized protein. (49 aa)
	T1I0I0_RHOPR	AAA domain-containing protein. (715 aa)
	T1I6D0_RHOPR	MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (81 aa)
	T1I7E7_RHOPR	Uncharacterized protein. (176 aa)
	T1I843_RHOPR	Peptidase_M41 domain-containing protein. (125 aa)
	T1I8P9_RHOPR	MCU domain-containing protein. (271 aa)
	T1ICL1_RHOPR	Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (313 aa)
	T1IED4_RHOPR	Uncharacterized protein; Belongs to the BI1 family. (311 aa)
	T1IGP9_RHOPR	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (107 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4FLU8_RHOPR	T1HC11_RHOPR	R4FLU8	T1HC11	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.	0.959
R4G424_RHOPR	T1H8J7_RHOPR	R4G424	T1H8J7	Uncharacterized protein.	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.844
R4G424_RHOPR	T1HAN2_RHOPR	R4G424	T1HAN2	Uncharacterized protein.	MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.668
R4G424_RHOPR	T1HAR5_RHOPR	R4G424	T1HAR5	Uncharacterized protein.	MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.984
R4G424_RHOPR	T1HF19_RHOPR	R4G424	T1HF19	Uncharacterized protein.	Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.	0.526
R4G424_RHOPR	T1HM68_RHOPR	R4G424	T1HM68	Uncharacterized protein.	MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.841
R4G424_RHOPR	T1I6D0_RHOPR	R4G424	T1I6D0	Uncharacterized protein.	MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.696
R4G424_RHOPR	T1I7E7_RHOPR	R4G424	T1I7E7	Uncharacterized protein.	Uncharacterized protein.	0.436
R4G7Y3_RHOPR	T1HD83_RHOPR	R4G7Y3	T1HD83	Putative mitochondrial import inner membrane translocase subunit tim23.	Uncharacterized protein.	0.479
R4G7Y3_RHOPR	T1HQP3_RHOPR	R4G7Y3	T1HQP3	Putative mitochondrial import inner membrane translocase subunit tim23.	Uncharacterized protein.	0.516
R4G7Y3_RHOPR	T1HR87_RHOPR	R4G7Y3	T1HR87	Putative mitochondrial import inner membrane translocase subunit tim23.	AAA domain-containing protein.	0.415
R4G7Y3_RHOPR	T1HX17_RHOPR	R4G7Y3	T1HX17	Putative mitochondrial import inner membrane translocase subunit tim23.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.650
R4G7Y3_RHOPR	T1HXP9_RHOPR	R4G7Y3	T1HXP9	Putative mitochondrial import inner membrane translocase subunit tim23.	Uncharacterized protein.	0.985
R4G7Y3_RHOPR	T1HXQ7_RHOPR	R4G7Y3	T1HXQ7	Putative mitochondrial import inner membrane translocase subunit tim23.	Uncharacterized protein.	0.985
R4G7Y3_RHOPR	T1I0I0_RHOPR	R4G7Y3	T1I0I0	Putative mitochondrial import inner membrane translocase subunit tim23.	AAA domain-containing protein.	0.404
R4G7Y3_RHOPR	T1I843_RHOPR	R4G7Y3	T1I843	Putative mitochondrial import inner membrane translocase subunit tim23.	Peptidase_M41 domain-containing protein.	0.415
R4G7Y3_RHOPR	T1I8P9_RHOPR	R4G7Y3	T1I8P9	Putative mitochondrial import inner membrane translocase subunit tim23.	MCU domain-containing protein.	0.519
R4G7Y3_RHOPR	coq2	R4G7Y3	T1HD81	Putative mitochondrial import inner membrane translocase subunit tim23.	4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.	0.516
T1H8J7_RHOPR	R4G424_RHOPR	T1H8J7	R4G424	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	Uncharacterized protein.	0.844
T1H8J7_RHOPR	T1HAN2_RHOPR	T1H8J7	T1HAN2	MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.	0.781