(44 nodes) Endosome transport via multivesicular body sorting pathway network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1HGI6_RHOPR	Uncharacterized protein. (264 aa)
	T1HEE4_RHOPR	Uncharacterized protein. (345 aa)
	T1HD61_RHOPR	BRO1 domain-containing protein. (946 aa)
	T1HCT8_RHOPR	Uncharacterized protein. (239 aa)
	T1HAM6_RHOPR	Uncharacterized protein. (308 aa)
	T1H8R0_RHOPR	Uncharacterized protein. (210 aa)
	R4G8R3_RHOPR	Uncharacterized protein. (356 aa)
	R4G8N9_RHOPR	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (244 aa)
	R4G5B7_RHOPR	Putative vacuolar sorting protein. (220 aa)
	R4G5A9_RHOPR	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (213 aa)
	R4G4L2_RHOPR	Uncharacterized protein. (219 aa)
	R4G4I1_RHOPR	Annexin. (323 aa)
	R4G3M0_RHOPR	Putative assembly/vacuolar sorting protein. (213 aa)
	R4FPV9_RHOPR	Putative small gtp binding protein rab5. (213 aa)
	R4FPM8_RHOPR	Putative vacuolar protein sorting 25. (171 aa)
	R4FNR0_RHOPR	Putative vacuolar assembly/sorting protein did2. (201 aa)
	R4FLR8_RHOPR	Putative transmembrane protein 50b. (159 aa)
	T1HQV7_RHOPR	Uncharacterized protein. (173 aa)
	T1IGH7_RHOPR	Uncharacterized protein. (436 aa)
	T1IEU2_RHOPR	Uncharacterized protein. (219 aa)
	T1IEQ6_RHOPR	Uncharacterized protein. (225 aa)
	T1ICG2_RHOPR	GLUE N-terminal domain-containing protein. (394 aa)
	T1IBR9_RHOPR	Uncharacterized protein. (317 aa)
	T1IBC3_RHOPR	Uncharacterized protein. (333 aa)
	T1IAK1_RHOPR	Hrs_helical domain-containing protein. (538 aa)
	T1I9M5_RHOPR	Uncharacterized protein. (220 aa)
	T1I7Q0_RHOPR	Uncharacterized protein. (188 aa)
	T1I7L5_RHOPR	Uncharacterized protein. (184 aa)
	T1I1T8_RHOPR	Uncharacterized protein. (302 aa)
	T1HZX8_RHOPR	Uncharacterized protein. (294 aa)
	T1HWX2_RHOPR	Uncharacterized protein. (62 aa)
	T1HWT1_RHOPR	Uncharacterized protein. (118 aa)
	T1HVL4_RHOPR	Uncharacterized protein. (116 aa)
	T1HU25_RHOPR	Uncharacterized protein. (142 aa)
	T1HU24_RHOPR	SH3 domain-containing protein. (284 aa)
	T1HU23_RHOPR	Uncharacterized protein. (170 aa)
	T1HU21_RHOPR	Uncharacterized protein. (575 aa)
	T1HU20_RHOPR	Uncharacterized protein. (273 aa)
	T1HU19_RHOPR	Uncharacterized protein. (113 aa)
	T1HTX9_RHOPR	PH domain-containing protein. (341 aa)
	T1HS59_RHOPR	UDENN domain-containing protein. (343 aa)
	T1HR31_RHOPR	Uncharacterized protein. (415 aa)
	T1HMW3_RHOPR	Uncharacterized protein. (328 aa)
	T1HMT3_RHOPR	Uncharacterized protein. (586 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4FLR8_RHOPR	T1HVL4_RHOPR	R4FLR8	T1HVL4	Putative transmembrane protein 50b.	Uncharacterized protein.	0.986
R4FNR0_RHOPR	R4FPM8_RHOPR	R4FNR0	R4FPM8	Putative vacuolar assembly/sorting protein did2.	Putative vacuolar protein sorting 25.	0.615
R4FNR0_RHOPR	R4G3M0_RHOPR	R4FNR0	R4G3M0	Putative vacuolar assembly/sorting protein did2.	Putative assembly/vacuolar sorting protein.	0.956
R4FNR0_RHOPR	R4G4L2_RHOPR	R4FNR0	R4G4L2	Putative vacuolar assembly/sorting protein did2.	Uncharacterized protein.	0.991
R4FNR0_RHOPR	R4G5A9_RHOPR	R4FNR0	R4G5A9	Putative vacuolar assembly/sorting protein did2.	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.	0.637
R4FNR0_RHOPR	R4G5B7_RHOPR	R4FNR0	R4G5B7	Putative vacuolar assembly/sorting protein did2.	Putative vacuolar sorting protein.	0.991
R4FNR0_RHOPR	R4G8N9_RHOPR	R4FNR0	R4G8N9	Putative vacuolar assembly/sorting protein did2.	Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.613
R4FNR0_RHOPR	R4G8R3_RHOPR	R4FNR0	R4G8R3	Putative vacuolar assembly/sorting protein did2.	Uncharacterized protein.	0.989
R4FNR0_RHOPR	T1H8R0_RHOPR	R4FNR0	T1H8R0	Putative vacuolar assembly/sorting protein did2.	Uncharacterized protein.	0.984
R4FNR0_RHOPR	T1HAM6_RHOPR	R4FNR0	T1HAM6	Putative vacuolar assembly/sorting protein did2.	Uncharacterized protein.	0.996
R4FNR0_RHOPR	T1HCT8_RHOPR	R4FNR0	T1HCT8	Putative vacuolar assembly/sorting protein did2.	Uncharacterized protein.	0.543
R4FNR0_RHOPR	T1HEE4_RHOPR	R4FNR0	T1HEE4	Putative vacuolar assembly/sorting protein did2.	Uncharacterized protein.	0.857
R4FNR0_RHOPR	T1HGI6_RHOPR	R4FNR0	T1HGI6	Putative vacuolar assembly/sorting protein did2.	Uncharacterized protein.	0.857
R4FNR0_RHOPR	T1HMW3_RHOPR	R4FNR0	T1HMW3	Putative vacuolar assembly/sorting protein did2.	Uncharacterized protein.	0.857
R4FNR0_RHOPR	T1HR31_RHOPR	R4FNR0	T1HR31	Putative vacuolar assembly/sorting protein did2.	Uncharacterized protein.	0.913
R4FNR0_RHOPR	T1HWT1_RHOPR	R4FNR0	T1HWT1	Putative vacuolar assembly/sorting protein did2.	Uncharacterized protein.	0.995
R4FNR0_RHOPR	T1HWX2_RHOPR	R4FNR0	T1HWX2	Putative vacuolar assembly/sorting protein did2.	Uncharacterized protein.	0.995
R4FNR0_RHOPR	T1HZX8_RHOPR	R4FNR0	T1HZX8	Putative vacuolar assembly/sorting protein did2.	Uncharacterized protein.	0.857
R4FNR0_RHOPR	T1I1T8_RHOPR	R4FNR0	T1I1T8	Putative vacuolar assembly/sorting protein did2.	Uncharacterized protein.	0.857
R4FNR0_RHOPR	T1I7Q0_RHOPR	R4FNR0	T1I7Q0	Putative vacuolar assembly/sorting protein did2.	Uncharacterized protein.	0.888