(9 nodes) Mitotic DNA replication checkpoint signaling network (Rhodnius prolixus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R4FKD6_RHOPR	Checkpoint protein; Belongs to the HUS1 family. (276 aa)
	T1HCL2_RHOPR	Ig-like domain-containing protein. (171 aa)
	T1HFU2_RHOPR	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (373 aa)
	T1HJS6_RHOPR	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (652 aa)
	T1HMD9_RHOPR	Uncharacterized protein. (344 aa)
	T1I0G2_RHOPR	DUF3385 domain-containing protein. (363 aa)
	T1I327_RHOPR	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (468 aa)
	T1I939_RHOPR	U1-type domain-containing protein. (293 aa)
	T1IBZ5_RHOPR	Uncharacterized protein. (395 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4FKD6_RHOPR	T1HJS6_RHOPR	R4FKD6	T1HJS6	Checkpoint protein; Belongs to the HUS1 family.	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.838
R4FKD6_RHOPR	T1HMD9_RHOPR	R4FKD6	T1HMD9	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.993
R4FKD6_RHOPR	T1I0G2_RHOPR	R4FKD6	T1I0G2	Checkpoint protein; Belongs to the HUS1 family.	DUF3385 domain-containing protein.	0.838
R4FKD6_RHOPR	T1I327_RHOPR	R4FKD6	T1I327	Checkpoint protein; Belongs to the HUS1 family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.821
T1HCL2_RHOPR	T1I327_RHOPR	T1HCL2	T1I327	Ig-like domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.469
T1HCL2_RHOPR	T1I939_RHOPR	T1HCL2	T1I939	Ig-like domain-containing protein.	U1-type domain-containing protein.	0.662
T1HCL2_RHOPR	T1IBZ5_RHOPR	T1HCL2	T1IBZ5	Ig-like domain-containing protein.	Uncharacterized protein.	0.542
T1HJS6_RHOPR	R4FKD6_RHOPR	T1HJS6	R4FKD6	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	Checkpoint protein; Belongs to the HUS1 family.	0.838
T1HJS6_RHOPR	T1HMD9_RHOPR	T1HJS6	T1HMD9	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.914
T1HJS6_RHOPR	T1I327_RHOPR	T1HJS6	T1I327	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.969
T1HJS6_RHOPR	T1IBZ5_RHOPR	T1HJS6	T1IBZ5	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	Uncharacterized protein.	0.778
T1HMD9_RHOPR	R4FKD6_RHOPR	T1HMD9	R4FKD6	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.993
T1HMD9_RHOPR	T1HJS6_RHOPR	T1HMD9	T1HJS6	Uncharacterized protein.	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.914
T1HMD9_RHOPR	T1I0G2_RHOPR	T1HMD9	T1I0G2	Uncharacterized protein.	DUF3385 domain-containing protein.	0.914
T1HMD9_RHOPR	T1I327_RHOPR	T1HMD9	T1I327	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.878
T1HMD9_RHOPR	T1IBZ5_RHOPR	T1HMD9	T1IBZ5	Uncharacterized protein.	Uncharacterized protein.	0.574
T1I0G2_RHOPR	R4FKD6_RHOPR	T1I0G2	R4FKD6	DUF3385 domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.838
T1I0G2_RHOPR	T1HMD9_RHOPR	T1I0G2	T1HMD9	DUF3385 domain-containing protein.	Uncharacterized protein.	0.914
T1I0G2_RHOPR	T1I327_RHOPR	T1I0G2	T1I327	DUF3385 domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.969
T1I0G2_RHOPR	T1IBZ5_RHOPR	T1I0G2	T1IBZ5	DUF3385 domain-containing protein.	Uncharacterized protein.	0.778