(24 nodes) Vascular endothelial growth factor receptor signaling pathway network (Rhodnius prolixus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1HQH8_RHOPR	Uncharacterized protein. (781 aa)
	T1HNF8_RHOPR	Uncharacterized protein; Belongs to the DOCK family. (1925 aa)
	T1HN36_RHOPR	Uncharacterized protein. (481 aa)
	T1HN03_RHOPR	Ig-like domain-containing protein. (235 aa)
	T1HM61_RHOPR	Uncharacterized protein. (241 aa)
	T1HJK8_RHOPR	Raf homolog kinase phl. (686 aa)
	T1HFU2_RHOPR	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (373 aa)
	T1HC75_RHOPR	Protein kinase domain-containing protein. (488 aa)
	R4G8I2_RHOPR	Putative eukaryotic translation initiation factor 4e binding protein eif4ebp. (113 aa)
	T1IFJ4_RHOPR	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (362 aa)
	T1IGB3_RHOPR	Uncharacterized protein. (535 aa)
	T1IGN1_RHOPR	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (419 aa)
	T1HSZ9_RHOPR	Uncharacterized protein. (219 aa)
	T1HU71_RHOPR	Mitogen-activated protein kinase. (389 aa)
	T1HXL4_RHOPR	Mitogen-activated protein kinase kinase kinase. (538 aa)
	T1HXR9_RHOPR	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2448 aa)
	T1HZ23_RHOPR	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1055 aa)
	T1I0P2_RHOPR	Uncharacterized protein. (262 aa)
	T1I3X2_RHOPR	Tyrosine-protein kinase Ksr. (918 aa)
	T1I409_RHOPR	Uncharacterized protein. (380 aa)
	T1I4F0_RHOPR	Uncharacterized protein. (1230 aa)
	T1I4G8_RHOPR	ELMO domain-containing protein. (730 aa)
	T1I5A4_RHOPR	SH2 domain-containing protein. (512 aa)
	T1IA05_RHOPR	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4G8I2_RHOPR	T1HXR9_RHOPR	R4G8I2	T1HXR9	Putative eukaryotic translation initiation factor 4e binding protein eif4ebp.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.864
R4G8I2_RHOPR	T1IGB3_RHOPR	R4G8I2	T1IGB3	Putative eukaryotic translation initiation factor 4e binding protein eif4ebp.	Uncharacterized protein.	0.605
R4G8I2_RHOPR	T1IGN1_RHOPR	R4G8I2	T1IGN1	Putative eukaryotic translation initiation factor 4e binding protein eif4ebp.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.572
T1HC75_RHOPR	T1HN36_RHOPR	T1HC75	T1HN36	Protein kinase domain-containing protein.	Uncharacterized protein.	0.496
T1HC75_RHOPR	T1HNF8_RHOPR	T1HC75	T1HNF8	Protein kinase domain-containing protein.	Uncharacterized protein; Belongs to the DOCK family.	0.534
T1HC75_RHOPR	T1HQH8_RHOPR	T1HC75	T1HQH8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.614
T1HC75_RHOPR	T1HSZ9_RHOPR	T1HC75	T1HSZ9	Protein kinase domain-containing protein.	Uncharacterized protein.	0.873
T1HC75_RHOPR	T1HZ23_RHOPR	T1HC75	T1HZ23	Protein kinase domain-containing protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.774
T1HC75_RHOPR	T1I0P2_RHOPR	T1HC75	T1I0P2	Protein kinase domain-containing protein.	Uncharacterized protein.	0.732
T1HC75_RHOPR	T1I409_RHOPR	T1HC75	T1I409	Protein kinase domain-containing protein.	Uncharacterized protein.	0.865
T1HC75_RHOPR	T1I4F0_RHOPR	T1HC75	T1I4F0	Protein kinase domain-containing protein.	Uncharacterized protein.	0.673
T1HC75_RHOPR	T1I4G8_RHOPR	T1HC75	T1I4G8	Protein kinase domain-containing protein.	ELMO domain-containing protein.	0.490
T1HFU2_RHOPR	T1HJK8_RHOPR	T1HFU2	T1HJK8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Raf homolog kinase phl.	0.997
T1HFU2_RHOPR	T1HSZ9_RHOPR	T1HFU2	T1HSZ9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.558
T1HFU2_RHOPR	T1HU71_RHOPR	T1HFU2	T1HU71	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase.	0.793
T1HFU2_RHOPR	T1HXL4_RHOPR	T1HFU2	T1HXL4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase kinase kinase.	0.746
T1HFU2_RHOPR	T1HXR9_RHOPR	T1HFU2	T1HXR9	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.419
T1HFU2_RHOPR	T1I3X2_RHOPR	T1HFU2	T1I3X2	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase Ksr.	0.987
T1HFU2_RHOPR	T1I4F0_RHOPR	T1HFU2	T1I4F0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.542
T1HFU2_RHOPR	T1IFJ4_RHOPR	T1HFU2	T1IFJ4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.937