(7 nodes) Behavioral response to cocaine network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1H831_RHOPR	Double-time; Belongs to the protein kinase superfamily. (359 aa)
	R4G464_RHOPR	Putative camp-dependent protein kinase r2. (378 aa)
	T1H956_RHOPR	Cycle. (700 aa)
	T1HDJ0_RHOPR	Circadian locomoter output cycles protein kaput (clock). (582 aa)
	T1HDJ1_RHOPR	Inactive, transient receptor potential ion channel; Belongs to the transient receptor (TC 1.A.4) family. (1013 aa)
	T1HVU8_RHOPR	Uncharacterized protein. (381 aa)
	T1I4P9_RHOPR	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (352 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
T1H831_RHOPR	T1H956_RHOPR	T1H831	T1H956	Double-time; Belongs to the protein kinase superfamily.	Cycle.	0.974
T1H831_RHOPR	T1HDJ0_RHOPR	T1H831	T1HDJ0	Double-time; Belongs to the protein kinase superfamily.	Circadian locomoter output cycles protein kaput (clock).	0.931
T1H956_RHOPR	T1H831_RHOPR	T1H956	T1H831	Cycle.	Double-time; Belongs to the protein kinase superfamily.	0.974
T1H956_RHOPR	T1HDJ0_RHOPR	T1H956	T1HDJ0	Cycle.	Circadian locomoter output cycles protein kaput (clock).	0.996
T1HDJ0_RHOPR	T1H831_RHOPR	T1HDJ0	T1H831	Circadian locomoter output cycles protein kaput (clock).	Double-time; Belongs to the protein kinase superfamily.	0.931
T1HDJ0_RHOPR	T1H956_RHOPR	T1HDJ0	T1H956	Circadian locomoter output cycles protein kaput (clock).	Cycle.	0.996