(9 nodes) Barbed-end actin filament capping network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	T1HQ04_RHOPR	HP domain-containing protein. (933 aa)
	R4G5G6_RHOPR	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (287 aa)
	T1HDS9_RHOPR	Uncharacterized protein. (802 aa)
	T1HIQ8_RHOPR	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (275 aa)
	T1HKR8_RHOPR	Uncharacterized protein. (201 aa)
	T1HKU6_RHOPR	Gelsolin-like domain-containing protein. (151 aa)
	T1HUL6_RHOPR	Uncharacterized protein. (715 aa)
	T1I6E0_RHOPR	HP domain-containing protein. (250 aa)
	T1IF96_RHOPR	Uncharacterized protein. (1245 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4G5G6_RHOPR	T1HIQ8_RHOPR	R4G5G6	T1HIQ8	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.999
T1HIQ8_RHOPR	R4G5G6_RHOPR	T1HIQ8	R4G5G6	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.999
T1HKR8_RHOPR	T1HKU6_RHOPR	T1HKR8	T1HKU6	Uncharacterized protein.	Gelsolin-like domain-containing protein.	0.943
T1HKR8_RHOPR	T1I6E0_RHOPR	T1HKR8	T1I6E0	Uncharacterized protein.	HP domain-containing protein.	0.930
T1HKU6_RHOPR	T1HKR8_RHOPR	T1HKU6	T1HKR8	Gelsolin-like domain-containing protein.	Uncharacterized protein.	0.943
T1HKU6_RHOPR	T1I6E0_RHOPR	T1HKU6	T1I6E0	Gelsolin-like domain-containing protein.	HP domain-containing protein.	0.918
T1I6E0_RHOPR	T1HKR8_RHOPR	T1I6E0	T1HKR8	HP domain-containing protein.	Uncharacterized protein.	0.930
T1I6E0_RHOPR	T1HKU6_RHOPR	T1I6E0	T1HKU6	HP domain-containing protein.	Gelsolin-like domain-containing protein.	0.918