(32 nodes) Regulation of binding network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	T1I6Q7_RHOPR	Uncharacterized protein. (159 aa)
	T1HT01_RHOPR	DUF3736 domain-containing protein. (268 aa)
	T1HT86_RHOPR	E2F_TDP domain-containing protein. (76 aa)
	T1HVA1_RHOPR	RB_A domain-containing protein. (602 aa)
	T1HVD8_RHOPR	Timeless. (888 aa)
	T1I5C0_RHOPR	Mic1 domain-containing protein. (634 aa)
	T1I663_RHOPR	Uncharacterized protein. (142 aa)
	T1IGK5_RHOPR	Nefa_Nip30_N domain-containing protein. (281 aa)
	T1I7H2_RHOPR	Fam20C domain-containing protein. (385 aa)
	T1I6Q8_RHOPR	Uncharacterized protein. (1185 aa)
	T1IFF1_RHOPR	Uncharacterized protein. (726 aa)
	T1IBT5_RHOPR	Uncharacterized protein. (660 aa)
	T1I8W3_RHOPR	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (386 aa)
	R4FM90_RHOPR	Putative short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (304 aa)
	R4FNQ6_RHOPR	Putative arrestin length. (407 aa)
	R4FNX0_RHOPR	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (723 aa)
	T1H8D0_RHOPR	Uncharacterized protein. (2138 aa)
	T1HBG7_RHOPR	ANK_REP_REGION domain-containing protein. (378 aa)
	T1H9V1_RHOPR	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (821 aa)
	T1HAY2_RHOPR	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (393 aa)
	T1HBU7_RHOPR	Uncharacterized protein. (224 aa)
	T1HD16_RHOPR	WAPL domain-containing protein. (1024 aa)
	T1HE46_RHOPR	Uncharacterized protein. (259 aa)
	T1HH83_RHOPR	Uncharacterized protein. (206 aa)
	T1HHN6_RHOPR	Uncharacterized protein. (112 aa)
	T1HHN7_RHOPR	Uncharacterized protein. (190 aa)
	T1HM26_RHOPR	Uncharacterized protein. (281 aa)
	T1HNA2_RHOPR	PID domain-containing protein. (130 aa)
	T1HQQ9_RHOPR	Uncharacterized protein. (199 aa)
	T1HR08_RHOPR	TFIIB-type domain-containing protein. (250 aa)
	T1HSH2_RHOPR	C2H2-type domain-containing protein. (126 aa)
	T1HSY6_RHOPR	Uncharacterized protein. (178 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4FNX0_RHOPR	T1HHN6_RHOPR	R4FNX0	T1HHN6	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	Uncharacterized protein.	0.497
R4FNX0_RHOPR	T1HHN7_RHOPR	R4FNX0	T1HHN7	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	Uncharacterized protein.	0.497
R4FNX0_RHOPR	T1HQQ9_RHOPR	R4FNX0	T1HQQ9	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	Uncharacterized protein.	0.673
R4FNX0_RHOPR	T1HVD8_RHOPR	R4FNX0	T1HVD8	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	Timeless.	0.420
R4FNX0_RHOPR	T1I663_RHOPR	R4FNX0	T1I663	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	Uncharacterized protein.	0.673
T1H8D0_RHOPR	T1HBU7_RHOPR	T1H8D0	T1HBU7	Uncharacterized protein.	Uncharacterized protein.	0.663
T1H8D0_RHOPR	T1HNA2_RHOPR	T1H8D0	T1HNA2	Uncharacterized protein.	PID domain-containing protein.	0.593
T1HAY2_RHOPR	T1HD16_RHOPR	T1HAY2	T1HD16	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	WAPL domain-containing protein.	0.602
T1HAY2_RHOPR	T1HVA1_RHOPR	T1HAY2	T1HVA1	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	RB_A domain-containing protein.	0.709
T1HAY2_RHOPR	T1I6Q8_RHOPR	T1HAY2	T1I6Q8	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	Uncharacterized protein.	0.656
T1HBU7_RHOPR	T1H8D0_RHOPR	T1HBU7	T1H8D0	Uncharacterized protein.	Uncharacterized protein.	0.663
T1HD16_RHOPR	T1HAY2_RHOPR	T1HD16	T1HAY2	WAPL domain-containing protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.602
T1HD16_RHOPR	T1I6Q8_RHOPR	T1HD16	T1I6Q8	WAPL domain-containing protein.	Uncharacterized protein.	0.992
T1HD16_RHOPR	T1I8W3_RHOPR	T1HD16	T1I8W3	WAPL domain-containing protein.	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.	0.602
T1HHN6_RHOPR	R4FNX0_RHOPR	T1HHN6	R4FNX0	Uncharacterized protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.497
T1HHN7_RHOPR	R4FNX0_RHOPR	T1HHN7	R4FNX0	Uncharacterized protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.497
T1HNA2_RHOPR	T1H8D0_RHOPR	T1HNA2	T1H8D0	PID domain-containing protein.	Uncharacterized protein.	0.593
T1HQQ9_RHOPR	R4FNX0_RHOPR	T1HQQ9	R4FNX0	Uncharacterized protein.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.673
T1HQQ9_RHOPR	T1HR08_RHOPR	T1HQQ9	T1HR08	Uncharacterized protein.	TFIIB-type domain-containing protein.	0.626
T1HR08_RHOPR	T1HQQ9_RHOPR	T1HR08	T1HQQ9	TFIIB-type domain-containing protein.	Uncharacterized protein.	0.626