(44 nodes) Intracellular protein transmembrane transport network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1IAR5_RHOPR	Uncharacterized protein; Belongs to the heat shock protein 70 family. (627 aa)
	R4G3Q0_RHOPR	Putative mitochondria associated granulocyte macrophage csf signaling molecule. (128 aa)
	R4G3F5_RHOPR	Putative 60 kDa heat shock protein; Belongs to the chaperonin (HSP60) family. (549 aa)
	R4FP27_RHOPR	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (374 aa)
	R4G3R8_RHOPR	Putative mitochondrial import receptor subunit tom20. (158 aa)
	R4G497_RHOPR	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
	R4G4R3_RHOPR	Putative translocase of outer mitochondrial membrane complex. (321 aa)
	R4G7Y3_RHOPR	Putative mitochondrial import inner membrane translocase subunit tim23. (196 aa)
	R4G8H2_RHOPR	Putative mitochondrial genome maintenance protein. (78 aa)
	T1H7R5_RHOPR	Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (59 aa)
	T1H9P4_RHOPR	Uncharacterized protein. (386 aa)
	T1HAS3_RHOPR	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (123 aa)
	T1HAS4_RHOPR	Uncharacterized protein. (362 aa)
	T1HAS6_RHOPR	Uncharacterized protein. (182 aa)
	T1HEA3_RHOPR	Peroxisome assembly protein 12; Required for protein import into peroxisomes. Belongs to the pex2/pex10/pex12 family. (323 aa)
	T1HEX3_RHOPR	AAA domain-containing protein; Belongs to the AAA ATPase family. (456 aa)
	T1HF59_RHOPR	Uncharacterized protein. (166 aa)
	T1HGY5_RHOPR	WD_REPEATS_REGION domain-containing protein. (321 aa)
	T1HGZ3_RHOPR	Plug_translocon domain-containing protein. (476 aa)
	T1HLZ4_RHOPR	J domain-containing protein. (325 aa)
	T1HLZ5_RHOPR	SEC63 domain-containing protein. (117 aa)
	T1HMV2_RHOPR	Uncharacterized protein. (151 aa)
	T1HP30_RHOPR	J domain-containing protein. (122 aa)
	T1HP54_RHOPR	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (234 aa)
	T1HPR1_RHOPR	C2 domain-containing protein. (1265 aa)
	T1HTK4_RHOPR	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (544 aa)
	T1HWE0_RHOPR	DNL-type domain-containing protein. (145 aa)
	SRP54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (505 aa)
	T1HXP9_RHOPR	Uncharacterized protein. (49 aa)
	T1HXQ7_RHOPR	Uncharacterized protein. (49 aa)
	T1HZD5_RHOPR	Uncharacterized protein. (479 aa)
	T1I137_RHOPR	RING-type domain-containing protein. (608 aa)
	T1I1V2_RHOPR	RING-type domain-containing protein. (289 aa)
	R4FKA1_RHOPR	Putative mitochondrial import receptor subunit tom22. (133 aa)
	R4FJG7_RHOPR	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (434 aa)
	G1K0D5_RHOPR	Putative preprotein translocase. (68 aa)
	T1IE84_RHOPR	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
	T1ICX4_RHOPR	TPR_REGION domain-containing protein. (650 aa)
	T1IBC2_RHOPR	J domain-containing protein. (568 aa)
	T1IAT6_RHOPR	Uncharacterized protein. (178 aa)
	T1IAB6_RHOPR	Uncharacterized protein; Belongs to the chaperonin (HSP60) family. (571 aa)
	T1I4X7_RHOPR	Uncharacterized protein. (168 aa)
	T1I3E4_RHOPR	SH3 domain-containing protein. (316 aa)
	T1I2M7_RHOPR	Uncharacterized protein. (567 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G1K0D5_RHOPR	R4G497_RHOPR	G1K0D5	R4G497	Putative preprotein translocase.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.998
G1K0D5_RHOPR	SRP54	G1K0D5	T1HX96	Putative preprotein translocase.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.554
G1K0D5_RHOPR	T1H9P4_RHOPR	G1K0D5	T1H9P4	Putative preprotein translocase.	Uncharacterized protein.	0.986
G1K0D5_RHOPR	T1HGZ3_RHOPR	G1K0D5	T1HGZ3	Putative preprotein translocase.	Plug_translocon domain-containing protein.	0.999
G1K0D5_RHOPR	T1HLZ4_RHOPR	G1K0D5	T1HLZ4	Putative preprotein translocase.	J domain-containing protein.	0.962
G1K0D5_RHOPR	T1HLZ5_RHOPR	G1K0D5	T1HLZ5	Putative preprotein translocase.	SEC63 domain-containing protein.	0.962
G1K0D5_RHOPR	T1HMV2_RHOPR	G1K0D5	T1HMV2	Putative preprotein translocase.	Uncharacterized protein.	0.962
G1K0D5_RHOPR	T1IE84_RHOPR	G1K0D5	T1IE84	Putative preprotein translocase.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.998
R4FJG7_RHOPR	R4FKA1_RHOPR	R4FJG7	R4FKA1	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	Putative mitochondrial import receptor subunit tom22.	0.837
R4FJG7_RHOPR	R4FP27_RHOPR	R4FJG7	R4FP27	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.923
R4FJG7_RHOPR	R4G3F5_RHOPR	R4FJG7	R4G3F5	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	Putative 60 kDa heat shock protein; Belongs to the chaperonin (HSP60) family.	0.569
R4FJG7_RHOPR	R4G3Q0_RHOPR	R4FJG7	R4G3Q0	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	Putative mitochondria associated granulocyte macrophage csf signaling molecule.	0.986
R4FJG7_RHOPR	R4G3R8_RHOPR	R4FJG7	R4G3R8	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	Putative mitochondrial import receptor subunit tom20.	0.605
R4FJG7_RHOPR	R4G4R3_RHOPR	R4FJG7	R4G4R3	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	Putative translocase of outer mitochondrial membrane complex.	0.728
R4FJG7_RHOPR	R4G7Y3_RHOPR	R4FJG7	R4G7Y3	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	Putative mitochondrial import inner membrane translocase subunit tim23.	0.988
R4FJG7_RHOPR	R4G8H2_RHOPR	R4FJG7	R4G8H2	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	Putative mitochondrial genome maintenance protein.	0.571
R4FJG7_RHOPR	T1H7R5_RHOPR	R4FJG7	T1H7R5	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	0.569
R4FJG7_RHOPR	T1HAS6_RHOPR	R4FJG7	T1HAS6	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	Uncharacterized protein.	0.422
R4FJG7_RHOPR	T1HF59_RHOPR	R4FJG7	T1HF59	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	Uncharacterized protein.	0.924
R4FJG7_RHOPR	T1HP30_RHOPR	R4FJG7	T1HP30	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	J domain-containing protein.	0.924