(40 nodes) Negative regulation of canonical Wnt signaling pathway network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1HE86_RHOPR	Uncharacterized protein. (930 aa)
	T1HHB8_RHOPR	HDAC_interact domain-containing protein. (1166 aa)
	T1IEC9_RHOPR	Uncharacterized protein; Belongs to the AAA ATPase family. (579 aa)
	T1HHL7_RHOPR	Uncharacterized protein. (389 aa)
	T1HHM0_RHOPR	Uncharacterized protein. (564 aa)
	T1HU38_RHOPR	ZnMc domain-containing protein. (531 aa)
	T1HRI9_RHOPR	Uncharacterized protein. (537 aa)
	T1HQ26_RHOPR	Uncharacterized protein. (729 aa)
	T1HNY8_RHOPR	Uncharacterized protein. (813 aa)
	T1HNC1_RHOPR	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa)
	T1HLF7_RHOPR	Uncharacterized protein. (47 aa)
	T1HLD3_RHOPR	Protein kinase domain-containing protein. (110 aa)
	T1HJ07_RHOPR	Uncharacterized protein. (129 aa)
	T1HIF8_RHOPR	Uncharacterized protein. (765 aa)
	A0A0H2UI43	Nemo. (315 aa)
	R4G4N6_RHOPR	Putative ras-like gtp-binding protein rhoa. (187 aa)
	R4G8L9_RHOPR	Putative ras-like gtp-binding protein rho1 isoform 1. (193 aa)
	T1H8G1_RHOPR	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (535 aa)
	T1HB09_RHOPR	Uncharacterized protein. (166 aa)
	T1HWK9_RHOPR	Supernumerary limbs. (509 aa)
	T1HWY4_RHOPR	CTCK domain-containing protein. (265 aa)
	T1HZ35_RHOPR	Tyrosine-protein kinase otk. (889 aa)
	T1I0R5_RHOPR	Uncharacterized protein. (106 aa)
	T1I2C6_RHOPR	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (864 aa)
	T1IER8_RHOPR	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (215 aa)
	T1I2X1_RHOPR	ZnMc domain-containing protein. (570 aa)
	T1I4A1_RHOPR	Uncharacterized protein. (801 aa)
	T1I5C4_RHOPR	HMG box domain-containing protein. (290 aa)
	T1I6H3_RHOPR	Uncharacterized protein. (371 aa)
	T1HCS2_RHOPR	Kazal-like domain-containing protein. (353 aa)
	T1HDI6_RHOPR	Uncharacterized protein. (1552 aa)
	T1HEJ3_RHOPR	TPR_REGION domain-containing protein. (553 aa)
	T1IFT0_RHOPR	Uncharacterized protein. (668 aa)
	T1IES0_RHOPR	Protein kinase domain-containing protein. (118 aa)
	T1IAX7_RHOPR	Uncharacterized protein. (706 aa)
	T1ICC4_RHOPR	Peptidase_M10 domain-containing protein. (150 aa)
	T1IE68_RHOPR	Uncharacterized protein. (170 aa)
	T1HUC4_RHOPR	Uncharacterized protein. (193 aa)
	T1HC50_RHOPR	SAM domain-containing protein. (317 aa)
	T1HC68_RHOPR	FERM domain-containing protein. (429 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0H2UI43	T1HZ35_RHOPR	A0A0H2UI43	T1HZ35	Nemo.	Tyrosine-protein kinase otk.	0.567
A0A0H2UI43	T1IAX7_RHOPR	A0A0H2UI43	T1IAX7	Nemo.	Uncharacterized protein.	0.445
R4G4N6_RHOPR	T1HNY8_RHOPR	R4G4N6	T1HNY8	Putative ras-like gtp-binding protein rhoa.	Uncharacterized protein.	0.896
R4G4N6_RHOPR	T1HZ35_RHOPR	R4G4N6	T1HZ35	Putative ras-like gtp-binding protein rhoa.	Tyrosine-protein kinase otk.	0.655
R4G4N6_RHOPR	T1I2C6_RHOPR	R4G4N6	T1I2C6	Putative ras-like gtp-binding protein rhoa.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.463
R4G4N6_RHOPR	T1I4A1_RHOPR	R4G4N6	T1I4A1	Putative ras-like gtp-binding protein rhoa.	Uncharacterized protein.	0.552
R4G4N6_RHOPR	T1IE68_RHOPR	R4G4N6	T1IE68	Putative ras-like gtp-binding protein rhoa.	Uncharacterized protein.	0.552
R4G4N6_RHOPR	T1IEC9_RHOPR	R4G4N6	T1IEC9	Putative ras-like gtp-binding protein rhoa.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.552
R4G8L9_RHOPR	T1HNY8_RHOPR	R4G8L9	T1HNY8	Putative ras-like gtp-binding protein rho1 isoform 1.	Uncharacterized protein.	0.896
R4G8L9_RHOPR	T1HZ35_RHOPR	R4G8L9	T1HZ35	Putative ras-like gtp-binding protein rho1 isoform 1.	Tyrosine-protein kinase otk.	0.655
R4G8L9_RHOPR	T1I2C6_RHOPR	R4G8L9	T1I2C6	Putative ras-like gtp-binding protein rho1 isoform 1.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.463
R4G8L9_RHOPR	T1I4A1_RHOPR	R4G8L9	T1I4A1	Putative ras-like gtp-binding protein rho1 isoform 1.	Uncharacterized protein.	0.552
R4G8L9_RHOPR	T1IE68_RHOPR	R4G8L9	T1IE68	Putative ras-like gtp-binding protein rho1 isoform 1.	Uncharacterized protein.	0.552
R4G8L9_RHOPR	T1IEC9_RHOPR	R4G8L9	T1IEC9	Putative ras-like gtp-binding protein rho1 isoform 1.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.552
T1HB09_RHOPR	T1HNY8_RHOPR	T1HB09	T1HNY8	Uncharacterized protein.	Uncharacterized protein.	0.896
T1HB09_RHOPR	T1HZ35_RHOPR	T1HB09	T1HZ35	Uncharacterized protein.	Tyrosine-protein kinase otk.	0.655
T1HB09_RHOPR	T1I2C6_RHOPR	T1HB09	T1I2C6	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.463
T1HB09_RHOPR	T1I4A1_RHOPR	T1HB09	T1I4A1	Uncharacterized protein.	Uncharacterized protein.	0.552
T1HB09_RHOPR	T1IE68_RHOPR	T1HB09	T1IE68	Uncharacterized protein.	Uncharacterized protein.	0.552
T1HB09_RHOPR	T1IEC9_RHOPR	T1HB09	T1IEC9	Uncharacterized protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.552