(18 nodes) Germline stem cell asymmetric division network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1HS20_RHOPR	Uncharacterized protein; Belongs to the DEAD box helicase family. (423 aa)
	R4FLG7_RHOPR	Putative wd40 repeat protein. (489 aa)
	R4FMS4_RHOPR	Putative ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
	R4G4G0_RHOPR	Putative spindle assembly checkpoint protein. (208 aa)
	R4G4L2_RHOPR	Uncharacterized protein. (219 aa)
	T1H861_RHOPR	Loquacious. (367 aa)
	T1H9S7_RHOPR	TPR_MLP1_2 domain-containing protein. (1641 aa)
	T1HCF6_RHOPR	Uncharacterized protein. (1156 aa)
	T1HMA4_RHOPR	ALMS_motif domain-containing protein. (326 aa)
	T1HMA5_RHOPR	Uncharacterized protein. (611 aa)
	T1IFI8_RHOPR	Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (386 aa)
	T1I9X7_RHOPR	Protein kinase domain-containing protein. (254 aa)
	T1I9B5_RHOPR	Uncharacterized protein. (219 aa)
	T1HX75_RHOPR	BRO1 domain-containing protein. (847 aa)
	T1HTG9_RHOPR	Uncharacterized protein. (136 aa)
	T1HT61_RHOPR	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (183 aa)
	T1HSQ9_RHOPR	Protein kinase domain-containing protein. (741 aa)
	T1HQR5_RHOPR	Calponin-homology (CH) domain-containing protein. (1402 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4FLG7_RHOPR	T1HS20_RHOPR	R4FLG7	T1HS20	Putative wd40 repeat protein.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.528
R4FMS4_RHOPR	R4G4G0_RHOPR	R4FMS4	R4G4G0	Putative ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	Putative spindle assembly checkpoint protein.	0.792
R4FMS4_RHOPR	T1I9X7_RHOPR	R4FMS4	T1I9X7	Putative ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	Protein kinase domain-containing protein.	0.693
R4G4G0_RHOPR	R4FMS4_RHOPR	R4G4G0	R4FMS4	Putative spindle assembly checkpoint protein.	Putative ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.	0.792
R4G4G0_RHOPR	T1HQR5_RHOPR	R4G4G0	T1HQR5	Putative spindle assembly checkpoint protein.	Calponin-homology (CH) domain-containing protein.	0.746
R4G4G0_RHOPR	T1HSQ9_RHOPR	R4G4G0	T1HSQ9	Putative spindle assembly checkpoint protein.	Protein kinase domain-containing protein.	0.994
R4G4G0_RHOPR	T1I9X7_RHOPR	R4G4G0	T1I9X7	Putative spindle assembly checkpoint protein.	Protein kinase domain-containing protein.	0.927
R4G4L2_RHOPR	T1HX75_RHOPR	R4G4L2	T1HX75	Uncharacterized protein.	BRO1 domain-containing protein.	0.997
R4G4L2_RHOPR	T1I9X7_RHOPR	R4G4L2	T1I9X7	Uncharacterized protein.	Protein kinase domain-containing protein.	0.422
T1H9S7_RHOPR	T1I9X7_RHOPR	T1H9S7	T1I9X7	TPR_MLP1_2 domain-containing protein.	Protein kinase domain-containing protein.	0.461
T1HQR5_RHOPR	R4G4G0_RHOPR	T1HQR5	R4G4G0	Calponin-homology (CH) domain-containing protein.	Putative spindle assembly checkpoint protein.	0.746
T1HQR5_RHOPR	T1HSQ9_RHOPR	T1HQR5	T1HSQ9	Calponin-homology (CH) domain-containing protein.	Protein kinase domain-containing protein.	0.934
T1HQR5_RHOPR	T1I9X7_RHOPR	T1HQR5	T1I9X7	Calponin-homology (CH) domain-containing protein.	Protein kinase domain-containing protein.	0.691
T1HS20_RHOPR	R4FLG7_RHOPR	T1HS20	R4FLG7	Uncharacterized protein; Belongs to the DEAD box helicase family.	Putative wd40 repeat protein.	0.528
T1HS20_RHOPR	T1IFI8_RHOPR	T1HS20	T1IFI8	Uncharacterized protein; Belongs to the DEAD box helicase family.	Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs.	0.403
T1HSQ9_RHOPR	R4G4G0_RHOPR	T1HSQ9	R4G4G0	Protein kinase domain-containing protein.	Putative spindle assembly checkpoint protein.	0.994
T1HSQ9_RHOPR	T1HQR5_RHOPR	T1HSQ9	T1HQR5	Protein kinase domain-containing protein.	Calponin-homology (CH) domain-containing protein.	0.934
T1HSQ9_RHOPR	T1I9X7_RHOPR	T1HSQ9	T1I9X7	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.797
T1HX75_RHOPR	R4G4L2_RHOPR	T1HX75	R4G4L2	BRO1 domain-containing protein.	Uncharacterized protein.	0.997
T1I9B5_RHOPR	T1I9X7_RHOPR	T1I9B5	T1I9X7	Uncharacterized protein.	Protein kinase domain-containing protein.	0.461