(110 nodes) Secretory vesicle network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	T1HLT9_RHOPR	DC_STAMP domain-containing protein. (674 aa)
	T1HM78_RHOPR	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (126 aa)
	T1HN32_RHOPR	ATPase_AAA_core domain-containing protein. (124 aa)
	T1HN95_RHOPR	GAE domain-containing protein. (833 aa)
	T1HP67_RHOPR	UDENN domain-containing protein. (1835 aa)
	T1HSF0_RHOPR	Uncharacterized protein. (210 aa)
	T1HTA2_RHOPR	Uncharacterized protein. (196 aa)
	T1HTW8_RHOPR	GuKc domain-containing protein. (481 aa)
	T1HUG0_RHOPR	Uncharacterized protein. (1416 aa)
	T1HUS6_RHOPR	Uncharacterized protein. (146 aa)
	T1HUS7_RHOPR	FerB domain-containing protein. (164 aa)
	T1HUT0_RHOPR	C2 domain-containing protein. (739 aa)
	T1HUU0_RHOPR	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (255 aa)
	T1HVZ9_RHOPR	Uncharacterized protein. (384 aa)
	T1HWS6_RHOPR	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (571 aa)
	T1HWW8_RHOPR	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (238 aa)
	T1HX54_RHOPR	Uncharacterized protein. (104 aa)
	T1HXA5_RHOPR	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. (522 aa)
	T1HXB0_RHOPR	V-SNARE coiled-coil homology domain-containing protein. (244 aa)
	T1HXD4_RHOPR	Uncharacterized protein. (511 aa)
	T1HXU3_RHOPR	Protein kinase domain-containing protein. (142 aa)
	T1HYD1_RHOPR	Zinc/iron regulated transporter. (340 aa)
	T1HYJ8_RHOPR	DOMON domain-containing protein. (646 aa)
	T1HZP8_RHOPR	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (185 aa)
	T1I0J8_RHOPR	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (254 aa)
	T1I0S3_RHOPR	Protein kinase domain-containing protein. (296 aa)
	T1I0T1_RHOPR	Clathrin-link domain-containing protein. (1603 aa)
	T1I0W6_RHOPR	Uncharacterized protein. (85 aa)
	T1I1E6_RHOPR	Uncharacterized protein. (401 aa)
	T1I1Y3_RHOPR	Uncharacterized protein. (743 aa)
	T1I3W4_RHOPR	Uncharacterized protein. (520 aa)
	T1I3X6_RHOPR	Uncharacterized protein. (213 aa)
	T1I443_RHOPR	Uncharacterized protein. (76 aa)
	T1I4I8_RHOPR	MFS domain-containing protein. (470 aa)
	T1I4P6_RHOPR	Protein kinase domain-containing protein. (283 aa)
	T1I5R1_RHOPR	Uncharacterized protein. (1932 aa)
	T1I675_RHOPR	Uncharacterized protein. (198 aa)
	T1I6E5_RHOPR	SOCS box domain-containing protein. (252 aa)
	T1I6V4_RHOPR	Uncharacterized protein. (542 aa)
	T1I743_RHOPR	Aa_trans domain-containing protein. (431 aa)
	T1I7D2_RHOPR	Tr-type G domain-containing protein. (563 aa)
	T1I7Q3_RHOPR	Uncharacterized protein. (496 aa)
	T1I7Q6_RHOPR	Uncharacterized protein. (271 aa)
	T1I857_RHOPR	Uncharacterized protein. (294 aa)
	T1I8Q3_RHOPR	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (588 aa)
	T1IAJ3_RHOPR	Uncharacterized protein. (109 aa)
	T1IAN6_RHOPR	Glass boat bottom. BMP ligand. (422 aa)
	T1IAP1_RHOPR	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (582 aa)
	T1IAV9_RHOPR	Uncharacterized protein. (1528 aa)
	T1IBN8_RHOPR	Dopamine 1-like receptor 2; Belongs to the G-protein coupled receptor 1 family. (341 aa)
	T1IBW8_RHOPR	Uncharacterized protein. (76 aa)
	T1IC95_RHOPR	Uncharacterized protein. (206 aa)
	T1ICX1_RHOPR	EF-hand domain-containing protein. (48 aa)
	T1IDR5_RHOPR	Hyaluronidase. (280 aa)
	T1IFQ6_RHOPR	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (360 aa)
	T1IFU4_RHOPR	ENTH domain-containing protein. (59 aa)
	T1IFW4_RHOPR	Uncharacterized protein. (148 aa)
	T1IG23_RHOPR	Enkurin domain-containing protein. (274 aa)
	T1IGB5_RHOPR	Uncharacterized protein. (1828 aa)
	T1HKX5_RHOPR	Uncharacterized protein. (106 aa)
	T1HKZ8_RHOPR	Secretory carrier-associated membrane protein. (143 aa)
	T1HL63_RHOPR	Hyaluronidase. (341 aa)
	T1HL87_RHOPR	Nudix hydrolase domain-containing protein. (170 aa)
	T1HLC4_RHOPR	Uncharacterized protein. (1052 aa)
	T1HM76_RHOPR	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (117 aa)
	T1IEV5_RHOPR	MFS domain-containing protein. (525 aa)
	T1IF65_RHOPR	C2 domain-containing protein. (114 aa)
	T1IF66_RHOPR	Uncharacterized protein. (230 aa)
	T1IDV0_RHOPR	DOMON domain-containing protein. (572 aa)
	T1IFE1_RHOPR	Uncharacterized protein. (1137 aa)
	T1IFJ1_RHOPR	Peptidase S1 domain-containing protein. (287 aa)
	R4FN30_RHOPR	Putative ras-related protein rab. (200 aa)
	R4G3J4_RHOPR	Putative alpha-l-fucosidase; Belongs to the glycosyl hydrolase 29 family. (471 aa)
	R4G4E1_RHOPR	Putative vesicle-associated membrane protein 2. (117 aa)
	R4G4G1_RHOPR	Putative calcineurin b. (170 aa)
	R4G4G2_RHOPR	Putative cysteine string protein. (217 aa)
	R4G4K8_RHOPR	Putative gtpase. (215 aa)
	R4G5K6_RHOPR	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family. (442 aa)
	R4G8M2_RHOPR	Putative rab-protein 10. (200 aa)
	T1H7U5_RHOPR	Peptidase S1 domain-containing protein. (174 aa)
	T1H9X2_RHOPR	Tyrosine-protein phosphatase domain-containing protein. (57 aa)
	T1HA05_RHOPR	Phorbol-ester/DAG-type domain-containing protein. (1833 aa)
	T1HA98_RHOPR	Uncharacterized protein. (343 aa)
	T1HAC9_RHOPR	MARVEL domain-containing protein. (497 aa)
	T1HAE2_RHOPR	Uncharacterized protein. (2274 aa)
	T1HAI0_RHOPR	Uncharacterized protein. (307 aa)
	T1HAI4_RHOPR	Uncharacterized protein. (388 aa)
	T1HAI5_RHOPR	Uncharacterized protein. (423 aa)
	T1HAT7_RHOPR	Uncharacterized protein. (352 aa)
	T1HAW5_RHOPR	Uncharacterized protein. (456 aa)
	T1HB67_RHOPR	MFS domain-containing protein. (382 aa)
	T1HC53_RHOPR	Uncharacterized protein. (1093 aa)
	T1HCG4_RHOPR	Uncharacterized protein; Belongs to the AAA ATPase family. (202 aa)
	T1HCY1_RHOPR	Uncharacterized protein. (365 aa)
	T1HCY3_RHOPR	Uncharacterized protein. (961 aa)
	T1HDB7_RHOPR	Uncharacterized protein. (192 aa)
	T1HDJ9_RHOPR	ENTH domain-containing protein. (707 aa)
	T1HDS3_RHOPR	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (558 aa)
	T1HFB6_RHOPR	Chloride channel protein. (745 aa)
	T1HG01_RHOPR	IGFBP N-terminal domain-containing protein. (154 aa)
	T1HGV8_RHOPR	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (291 aa)
	T1HHI6_RHOPR	C2 domain-containing protein. (324 aa)
	T1HHM1_RHOPR	Uncharacterized protein. (70 aa)
	T1HI99_RHOPR	Uncharacterized protein. (222 aa)
	T1HIT2_RHOPR	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (53 aa)
	T1HK15_RHOPR	Uncharacterized protein. (2715 aa)
	T1HKD5_RHOPR	Uncharacterized protein. (101 aa)
	T1HKE1_RHOPR	Uncharacterized protein. (191 aa)
	T1HKG4_RHOPR	Uncharacterized protein. (594 aa)
	T1HKJ9_RHOPR	Sec2p domain-containing protein. (332 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4FN30_RHOPR	R4G4K8_RHOPR	R4FN30	R4G4K8	Putative ras-related protein rab.	Putative gtpase.	0.546
R4FN30_RHOPR	R4G5K6_RHOPR	R4FN30	R4G5K6	Putative ras-related protein rab.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.864
R4FN30_RHOPR	T1HI99_RHOPR	R4FN30	T1HI99	Putative ras-related protein rab.	Uncharacterized protein.	0.508
R4FN30_RHOPR	T1HP67_RHOPR	R4FN30	T1HP67	Putative ras-related protein rab.	UDENN domain-containing protein.	0.558
R4FN30_RHOPR	T1HSF0_RHOPR	R4FN30	T1HSF0	Putative ras-related protein rab.	Uncharacterized protein.	0.535
R4FN30_RHOPR	T1HXA5_RHOPR	R4FN30	T1HXA5	Putative ras-related protein rab.	Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.	0.742
R4G4E1_RHOPR	R4G4G2_RHOPR	R4G4E1	R4G4G2	Putative vesicle-associated membrane protein 2.	Putative cysteine string protein.	0.719
R4G4E1_RHOPR	R4G4K8_RHOPR	R4G4E1	R4G4K8	Putative vesicle-associated membrane protein 2.	Putative gtpase.	0.582
R4G4E1_RHOPR	R4G8M2_RHOPR	R4G4E1	R4G8M2	Putative vesicle-associated membrane protein 2.	Putative rab-protein 10.	0.633
R4G4E1_RHOPR	T1HA05_RHOPR	R4G4E1	T1HA05	Putative vesicle-associated membrane protein 2.	Phorbol-ester/DAG-type domain-containing protein.	0.741
R4G4E1_RHOPR	T1HAE2_RHOPR	R4G4E1	T1HAE2	Putative vesicle-associated membrane protein 2.	Uncharacterized protein.	0.666
R4G4E1_RHOPR	T1HAI0_RHOPR	R4G4E1	T1HAI0	Putative vesicle-associated membrane protein 2.	Uncharacterized protein.	0.686
R4G4E1_RHOPR	T1HAI4_RHOPR	R4G4E1	T1HAI4	Putative vesicle-associated membrane protein 2.	Uncharacterized protein.	0.668
R4G4E1_RHOPR	T1HAI5_RHOPR	R4G4E1	T1HAI5	Putative vesicle-associated membrane protein 2.	Uncharacterized protein.	0.707
R4G4E1_RHOPR	T1HAW5_RHOPR	R4G4E1	T1HAW5	Putative vesicle-associated membrane protein 2.	Uncharacterized protein.	0.859
R4G4E1_RHOPR	T1HB67_RHOPR	R4G4E1	T1HB67	Putative vesicle-associated membrane protein 2.	MFS domain-containing protein.	0.546
R4G4E1_RHOPR	T1HCG4_RHOPR	R4G4E1	T1HCG4	Putative vesicle-associated membrane protein 2.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.616
R4G4E1_RHOPR	T1HCY1_RHOPR	R4G4E1	T1HCY1	Putative vesicle-associated membrane protein 2.	Uncharacterized protein.	0.499
R4G4E1_RHOPR	T1HDJ9_RHOPR	R4G4E1	T1HDJ9	Putative vesicle-associated membrane protein 2.	ENTH domain-containing protein.	0.726
R4G4E1_RHOPR	T1HDS3_RHOPR	R4G4E1	T1HDS3	Putative vesicle-associated membrane protein 2.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.463