(8 nodes) WNT mediated activation of DVL network (Rhodnius prolixus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	R4G4B8_RHOPR	Putative casein kinase ii; Belongs to the protein kinase superfamily. (353 aa)
	T1I5E7_RHOPR	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (156 aa)
	T1I5D3_RHOPR	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (122 aa)
	T1HUU2_RHOPR	Casein kinase II alpha subunit; Belongs to the protein kinase superfamily. (355 aa)
	T1HII0_RHOPR	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (347 aa)
	T1I6V0_RHOPR	Uncharacterized protein. (693 aa)
	T1H831_RHOPR	Double-time; Belongs to the protein kinase superfamily. (359 aa)
	T1HHL0_RHOPR	PIPK domain-containing protein. (484 aa)

Your Current Organism:

Rhodnius prolixus

NCBI taxonomy Id: 13249
Other names: R. prolixus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
R4G4B8_RHOPR	T1I5D3_RHOPR	R4G4B8	T1I5D3	Putative casein kinase ii; Belongs to the protein kinase superfamily.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.986
R4G4B8_RHOPR	T1I5E7_RHOPR	R4G4B8	T1I5E7	Putative casein kinase ii; Belongs to the protein kinase superfamily.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.986
R4G4B8_RHOPR	T1I6V0_RHOPR	R4G4B8	T1I6V0	Putative casein kinase ii; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.914
T1H831_RHOPR	T1I5D3_RHOPR	T1H831	T1I5D3	Double-time; Belongs to the protein kinase superfamily.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.408
T1H831_RHOPR	T1I5E7_RHOPR	T1H831	T1I5E7	Double-time; Belongs to the protein kinase superfamily.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.408
T1H831_RHOPR	T1I6V0_RHOPR	T1H831	T1I6V0	Double-time; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.857
T1HHL0_RHOPR	T1I6V0_RHOPR	T1HHL0	T1I6V0	PIPK domain-containing protein.	Uncharacterized protein.	0.697
T1HII0_RHOPR	T1I5D3_RHOPR	T1HII0	T1I5D3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.986
T1HII0_RHOPR	T1I5E7_RHOPR	T1HII0	T1I5E7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.986
T1HII0_RHOPR	T1I6V0_RHOPR	T1HII0	T1I6V0	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.914
T1HUU2_RHOPR	T1I5D3_RHOPR	T1HUU2	T1I5D3	Casein kinase II alpha subunit; Belongs to the protein kinase superfamily.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.986
T1HUU2_RHOPR	T1I5E7_RHOPR	T1HUU2	T1I5E7	Casein kinase II alpha subunit; Belongs to the protein kinase superfamily.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.986
T1HUU2_RHOPR	T1I6V0_RHOPR	T1HUU2	T1I6V0	Casein kinase II alpha subunit; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.914
T1I5D3_RHOPR	R4G4B8_RHOPR	T1I5D3	R4G4B8	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Putative casein kinase ii; Belongs to the protein kinase superfamily.	0.986
T1I5D3_RHOPR	T1H831_RHOPR	T1I5D3	T1H831	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Double-time; Belongs to the protein kinase superfamily.	0.408
T1I5D3_RHOPR	T1HII0_RHOPR	T1I5D3	T1HII0	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.986
T1I5D3_RHOPR	T1HUU2_RHOPR	T1I5D3	T1HUU2	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Casein kinase II alpha subunit; Belongs to the protein kinase superfamily.	0.986
T1I5D3_RHOPR	T1I5E7_RHOPR	T1I5D3	T1I5E7	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	0.933
T1I5D3_RHOPR	T1I6V0_RHOPR	T1I5D3	T1I6V0	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Uncharacterized protein.	0.896
T1I5E7_RHOPR	R4G4B8_RHOPR	T1I5E7	R4G4B8	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.	Putative casein kinase ii; Belongs to the protein kinase superfamily.	0.986