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| | cobT | Unannotated protein; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (341 aa) |
| | GCA_001418025_00644 | Unannotated protein; Belongs to the precorrin methyltransferase family. (249 aa) |
| | GCA_001418025_00645 | Unannotated protein. (173 aa) |
| | carA | Unannotated protein; Belongs to the CarA family. (355 aa) |
| | carB | Unannotated protein. (1034 aa) |
| | GCA_001418025_00697 | Unannotated protein. (212 aa) |
| | nadK-2 | Unannotated protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (263 aa) |
| | GCA_001418025_00709 | Unannotated protein. (423 aa) |
| | GCA_001418025_00763 | Unannotated protein. (223 aa) |
| | dinG | Unannotated protein; 3'-5' exonuclease. (881 aa) |
| | aroA | Unannotated protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (428 aa) |
| | GCA_001418025_00790 | Unannotated protein. (367 aa) |
| | trpA | Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (279 aa) |
| | trpB | Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (398 aa) |
| | trpF | Unannotated protein; Belongs to the TrpF family. (211 aa) |
| | trpC | Unannotated protein; Belongs to the TrpC family. (253 aa) |
| | trpD | Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (336 aa) |
| | trpE | Unannotated protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (501 aa) |
| | GCA_001418025_00798 | Unannotated protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (126 aa) |
| | aroB | Unannotated protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (379 aa) |
| | aroC | Unannotated protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (389 aa) |
| | ndk | Unannotated protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (148 aa) |
| | GCA_001418025_00806 | Unannotated protein. (74 aa) |
| | folE | Unannotated protein. (184 aa) |
| | cmk | Unannotated protein. (225 aa) |
| | GCA_001418025_00845 | Unannotated protein. (233 aa) |
| | GCA_001418025_00847 | Unannotated protein; Belongs to the Cob(I)alamin adenosyltransferase family. (193 aa) |
| | GCA_001418025_00848 | Unannotated protein. (142 aa) |
| | cobS | Unannotated protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (247 aa) |
| | GCA_001418025_00851 | Unannotated protein. (183 aa) |
| | GCA_001418025_00852 | Unannotated protein. (351 aa) |
| | cobD | Unannotated protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (310 aa) |
| | GCA_001418025_00892 | Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (245 aa) |
| | murA | Unannotated protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (432 aa) |
| | atpC | Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. (134 aa) |
| | atpD | Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (473 aa) |
| | atpG | Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (286 aa) |
| | atpA | Unannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (504 aa) |
| | atpH | Unannotated protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (178 aa) |
| | atpF | Unannotated protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (169 aa) |
| | atpE | Unannotated protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (70 aa) |
| | atpB | Unannotated protein; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (236 aa) |
| | upp | Unannotated protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) |
| | tdk | Unannotated protein. (206 aa) |
| | rho | Unannotated protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (428 aa) |
| | murA-2 | Unannotated protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (428 aa) |
| | pyrG | Unannotated protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (531 aa) |
| | GCA_001418025_00992 | Unannotated protein; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. (152 aa) |
| | GCA_001418025_01015 | Unannotated protein. (327 aa) |
| | GCA_001418025_01017 | Unannotated protein; May function as heme-dependent peroxidase. (248 aa) |
| | GCA_001418025_01041 | Unannotated protein. (407 aa) |
| | purA | Unannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa) |
| | GCA_001418025_01074 | Unannotated protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (454 aa) |
| | GCA_001418025_01098 | Unannotated protein; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication [...] (378 aa) |
| | dxs | Unannotated protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (630 aa) |
| | folD | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa) |
| | nusB | Unannotated protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (128 aa) |
| | GCA_001418025_01148 | Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa) |
| | aroQ | Unannotated protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (148 aa) |
| | GCA_001418025_01170 | Unannotated protein; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (853 aa) |
| | aroK | Unannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (168 aa) |
| | GCA_001418025_01202 | Unannotated protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (190 aa) |
| | sigA | Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (372 aa) |
| | dnaG | Unannotated protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (604 aa) |
| | GCA_001418025_01259 | Unannotated protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (380 aa) |
| | GCA_001418025_01265 | Unannotated protein. (319 aa) |
| | GCA_001418025_01273 | Unannotated protein. (191 aa) |
| | nadD | Unannotated protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (188 aa) |
| | aroE | Unannotated protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (275 aa) |
| | GCA_001418025_01285 | Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (238 aa) |
| | GCA_001418025_01371 | Unannotated protein; Belongs to the ribF family. (323 aa) |
| | nusA | Unannotated protein; Participates in both transcription termination and antitermination. (367 aa) |
| | polC | Unannotated protein; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1430 aa) |
| | pyrH | Unannotated protein; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa) |
| | GCA_001418025_01392 | Unannotated protein; Belongs to the sigma-70 factor family. (243 aa) |
| | GCA_001418025_01419 | Unannotated protein. (437 aa) |
| | GCA_001418025_01462 | Unannotated protein. (212 aa) |
| | priA | Unannotated protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (804 aa) |
| | GCA_001418025_01472 | Unannotated protein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (400 aa) |
| | rpoZ | Unannotated protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (69 aa) |
| | gmk | Unannotated protein; Essential for recycling GMP and indirectly, cGMP. (206 aa) |
| | trpB-2 | Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (387 aa) |
| | GCA_001418025_01544 | Unannotated protein. (406 aa) |
| | GCA_001418025_01552 | Unannotated protein. (239 aa) |
| | thiM | Unannotated protein; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (286 aa) |
| | thiE | Unannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (217 aa) |
| | GCA_001418025_01634 | Unannotated protein. (306 aa) |
| | cinA | Unannotated protein; Belongs to the CinA family. (410 aa) |
| | GCA_001418025_01695 | Unannotated protein. (373 aa) |
| | Ga0061060_1121 | Unannotated protein. (268 aa) |
| | thyA | Unannotated protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) |
| | GCA_001418025_01939 | Unannotated protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (162 aa) |
| | purU | Unannotated protein; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (299 aa) |
| | purE | Unannotated protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (162 aa) |
| | purK | Unannotated protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (382 aa) |
| | Ga0061060_1146 | Unannotated protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa) |
| | purC | Unannotated protein; Belongs to the SAICAR synthetase family. (240 aa) |
| | purS | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (84 aa) |
| | purQ | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (228 aa) |
| | purL | Unannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (740 aa) |
| | purF | Unannotated protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (475 aa) |
| | purM | Unannotated protein. (345 aa) |
| | purN | Unannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (200 aa) |
| | purH | Unannotated protein. (511 aa) |
| | purD | Unannotated protein; Belongs to the GARS family. (426 aa) |
| | GCA_001418025_02126 | Unannotated protein. (433 aa) |
| | GCA_001418025_02155 | Unannotated protein. (426 aa) |
| | Ga0061060_1177 | Unannotated protein; Belongs to the sigma-70 factor family. ECF subfamily. (161 aa) |
| | GCA_001418025_02211 | Unannotated protein. (165 aa) |
| | GCA_001418025_02212 | Unannotated protein. (235 aa) |
| | GCA_001418025_02213 | Unannotated protein; Belongs to the precorrin methyltransferase family. (257 aa) |
| | pheA | Unannotated protein. (287 aa) |
| | GCA_001418025_02273 | Unannotated protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. (510 aa) |
| | GCA_001418025_02274 | Unannotated protein; Belongs to the NadC/ModD family. (276 aa) |
| | nadA | Unannotated protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (367 aa) |
| | nadE | Unannotated protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (246 aa) |
| | GCA_001418025_02283 | Unannotated protein. (68 aa) |
| | queA | Unannotated protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (343 aa) |
| | tgt | Unannotated protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. [...] (379 aa) |
| | apt | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa) |
| | GCA_001418025_02295 | Unannotated protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (732 aa) |
| | Ga0061060_1194 | Unannotated protein. (178 aa) |
| | Ga0061060_1195 | Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa) |
| | Ga0061060_1196 | Unannotated protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (278 aa) |
| | Ga0061060_1197 | Unannotated protein. (289 aa) |
| | trpE-2 | Unannotated protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (474 aa) |
| | coaX | Unannotated protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (257 aa) |
| | GCA_001418025_02310 | Unannotated protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (181 aa) |
| | prs | Unannotated protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (316 aa) |
| | glmU | Unannotated protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (458 aa) |
| | GCA_001418025_02346 | Unannotated protein. (332 aa) |
| | tmk | Unannotated protein; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (209 aa) |
| | GCA_001418025_02373 | Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (239 aa) |
| | GCA_001418025_02374 | Unannotated protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (259 aa) |
| | pyrR | Unannotated protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (178 aa) |
| | pyrB | Unannotated protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (307 aa) |
| | pyrC | Unannotated protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (428 aa) |
| | carA-2 | Unannotated protein; Belongs to the CarA family. (364 aa) |
| | carB-2 | Unannotated protein; Belongs to the CarB family. (1063 aa) |
| | pyrK | Unannotated protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (254 aa) |
| | pyrD | Unannotated protein; Catalyzes the conversion of dihydroorotate to orotate. (312 aa) |
| | pyrF | Unannotated protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (237 aa) |
| | pyrE | Unannotated protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (204 aa) |
| | udk | Unannotated protein. (211 aa) |
| | Ga0061060_1229 | Unannotated protein. (453 aa) |
| | rpoC | Unannotated protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1199 aa) |
| | rpoB | Unannotated protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1186 aa) |
| | nusG | Unannotated protein; Participates in transcription elongation, termination and antitermination. (177 aa) |
| | GCA_001418025_02486 | Unannotated protein; Belongs to the sigma-70 factor family. (216 aa) |
| | hemL-2 | Unannotated protein. (431 aa) |
| | dacA | Unannotated protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (273 aa) |
| | GCA_001418025_02554 | Unannotated protein; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa) |
| | Ga0061060_1261 | Unannotated protein. (260 aa) |
| | adk | Unannotated protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (216 aa) |
| | guaA | Unannotated protein; Catalyzes the synthesis of GMP from XMP. (506 aa) |
| | guaB | Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa) |
| | pdxS | Unannotated protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (294 aa) |
| | pdxT | Unannotated protein; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (192 aa) |
| | serS | Unannotated protein; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (424 aa) |
| | GCA_001418025_02620 | Unannotated protein. (222 aa) |
| | GCA_001418025_02621 | Unannotated protein. (212 aa) |
| | dnaX | Unannotated protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (559 aa) |
| | GCA_001418025_02636 | Unannotated protein. (264 aa) |
| | GCA_001418025_02673 | Unannotated protein. (243 aa) |
| | Ga0061060_1324 | Unannotated protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (227 aa) |
| | GCA_001418025_00228 | Unannotated protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (345 aa) |
| | Ga0061060_1017 | Unannotated protein; Belongs to the folylpolyglutamate synthase family. (434 aa) |
| | hemL | Unannotated protein. (431 aa) |
| | GCA_001418025_00012 | Unannotated protein; Belongs to the ALAD family. (324 aa) |
| | GCA_001418025_00013 | Unannotated protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (249 aa) |
| | hemC | Unannotated protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (308 aa) |
| | hemA | Unannotated protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (444 aa) |
| | ilvE | Unannotated protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (300 aa) |
| | GCA_001418025_00061 | Unannotated protein. (569 aa) |
| | GCA_001418025_00089 | Unannotated protein. (310 aa) |
| | GCA_001418025_00090 | Unannotated protein. (465 aa) |
| | coaE | Unannotated protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (203 aa) |
| | polA | Unannotated protein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. (875 aa) |
| | accA | Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa) |
| | accD | Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa) |
| | GCA_001418025_00114 | Unannotated protein; Belongs to the DNA polymerase type-C family. (1073 aa) |
| | ackA | Unannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa) |
| | nadK | Unannotated protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (267 aa) |
| | thiI | Unannotated protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (397 aa) |
| | GCA_001418025_00158 | Unannotated protein. (360 aa) |
| | GCA_001418025_00165 | Unannotated protein; Belongs to the NAPRTase family. (369 aa) |
| | GCA_001418025_00215 | Unannotated protein. (256 aa) |
| | GCA_001418025_00222 | Unannotated protein. (393 aa) |
| | cobQ | Unannotated protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (504 aa) |
| | cbiA | Unannotated protein; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (452 aa) |
| | GCA_001418025_00640 | Unannotated protein. (359 aa) |
| | GCA_001418025_00639 | Unannotated protein; Belongs to the precorrin methyltransferase family. (255 aa) |
| | GCA_001418025_00638 | Unannotated protein; Belongs to the precorrin methyltransferase family. (233 aa) |
| | GCA_001418025_00637 | Unannotated protein. (401 aa) |
| | cbiD | Unannotated protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (370 aa) |
| | GCA_001418025_00635 | Unannotated protein. (215 aa) |
| | GCA_001418025_00634 | Unannotated protein. (258 aa) |
| | GCA_001418025_00633 | Unannotated protein. (279 aa) |
| | GCA_001418025_00632 | Unannotated protein. (508 aa) |
| | cbiN | Unannotated protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family. (89 aa) |
| | cbiM | Unannotated protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import. (250 aa) |
| | GCA_001418025_00578 | Unannotated protein. (220 aa) |
| | GCA_001418025_00563 | Unannotated protein; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (472 aa) |
| | hemH | Unannotated protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (315 aa) |
| | hemE | Unannotated protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (346 aa) |
| | GCA_001418025_00544 | Unannotated protein. (499 aa) |
| | GCA_001418025_00533 | Unannotated protein. (265 aa) |
| | GCA_001418025_00532 | Unannotated protein. (338 aa) |
| | thiG | Unannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (256 aa) |
| | GCA_001418025_00530 | Unannotated protein. (67 aa) |
| | GCA_001418025_00529 | Unannotated protein. (373 aa) |
| | GCA_001418025_00528 | Unannotated protein. (204 aa) |
| | GCA_001418025_00524 | Unannotated protein; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family. (231 aa) |
| | queG | Unannotated protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (378 aa) |
| | GCA_001418025_00466 | Unannotated protein. (143 aa) |
| | queC | Unannotated protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). (219 aa) |
| | GCA_001418025_00368 | Unannotated protein. (145 aa) |
| | queE | Unannotated protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (240 aa) |
| | GCA_001418025_00366 | Unannotated protein. (55 aa) |
| | queF | Unannotated protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (110 aa) |
| | GCA_001418025_00359 | Unannotated protein; Belongs to the sigma-70 factor family. ECF subfamily. (161 aa) |
| | GCA_001418025_00295 | Unannotated protein; Belongs to the UPF0356 family. (71 aa) |
| | ctaA | Unannotated protein; Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group; Belongs to the COX15/CtaA family. Type 1 subfamily. (315 aa) |
| | ctaB | Unannotated protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. (301 aa) |
| | coaD | Unannotated protein; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (165 aa) |
| | menF | Unannotated protein; Catalyzes the conversion of chorismate to isochorismate. (451 aa) |
