STRINGSTRING
aroC aroC Ga0061060_1194 Ga0061060_1194 nadA nadA pheA pheA GCA_001418025_02228 GCA_001418025_02228 cysH cysH hisZ hisZ hisG hisG hisD hisD hisB hisB hisH hisH hisA hisA hisF hisF hisI hisI GCA_001418025_02126 GCA_001418025_02126 GCA_001418025_02105 GCA_001418025_02105 rocA-2 rocA-2 proB-2 proB-2 proA-2 proA-2 GCA_001418025_02022 GCA_001418025_02022 ilvD ilvD GCA_001418025_02013 GCA_001418025_02013 GCA_001418025_02012 GCA_001418025_02012 Ga0061060_1136 Ga0061060_1136 ilvA ilvA GCA_001418025_01939 GCA_001418025_01939 metAA metAA Ga0061060_1121 Ga0061060_1121 lipA lipA GCA_001418025_01784 GCA_001418025_01784 GCA_001418025_01783 GCA_001418025_01783 thrB thrB dapF dapF GCA_001418025_01743 GCA_001418025_01743 cysI cysI GCA_001418025_01696 GCA_001418025_01696 GCA_001418025_01685 GCA_001418025_01685 GCA_001418025_01682 GCA_001418025_01682 GCA_001418025_01651 GCA_001418025_01651 GCA_001418025_01626 GCA_001418025_01626 GCA_001418025_01617 GCA_001418025_01617 bioB bioB GCA_001418025_01566 GCA_001418025_01566 GCA_001418025_01556 GCA_001418025_01556 trpB-2 trpB-2 proB proB proA proA fapR fapR plsX plsX GCA_001418025_01453 GCA_001418025_01453 acpP acpP asd asd GCA_001418025_01362 GCA_001418025_01362 Ga0061060_1073 Ga0061060_1073 aroE aroE proC-2 proC-2 aroK aroK lipM lipM aroQ aroQ GCA_001418025_01149 GCA_001418025_01149 GCA_001418025_01148 GCA_001418025_01148 folD folD argR argR proC proC Ga0061060_1062 Ga0061060_1062 lipL lipL glyA glyA fabZ fabZ lysA lysA GCA_001418025_00844 GCA_001418025_00844 GCA_001418025_00843 GCA_001418025_00843 bioD bioD bioA bioA aroB aroB GCA_001418025_00798 GCA_001418025_00798 trpE trpE trpD trpD trpC trpC trpF trpF trpB trpB trpA trpA hisC hisC GCA_001418025_00790 GCA_001418025_00790 aroA aroA dapB dapB GCA_001418025_00776 GCA_001418025_00776 panB panB panC panC panD panD GCA_001418025_00738 GCA_001418025_00738 bioC bioC GCA_001418025_00709 GCA_001418025_00709 GCA_001418025_00703 GCA_001418025_00703 GCA_001418025_00674 GCA_001418025_00674 fabH fabH GCA_001418025_00667 GCA_001418025_00667 carB carB carA carA argD argD argB argB argJ argJ argC argC GCA_001418025_00646 GCA_001418025_00646 GCA_001418025_00610 GCA_001418025_00610 rocD rocD GCA_001418025_00558 GCA_001418025_00558 serC serC mtnA mtnA mtnK mtnK mtnW mtnW mtnX mtnX mtnB mtnB mtnD mtnD dapH dapH GCA_001418025_00300 GCA_001418025_00300 menF menF GCA_001418025_00205 GCA_001418025_00205 GCA_001418025_00147 GCA_001418025_00147 argG argG argH argH GCA_001418025_00122 GCA_001418025_00122 accD accD accA accA ilvE ilvE GCA_001418025_00030 GCA_001418025_00030 GCA_001418025_00029 GCA_001418025_00029 ilvC ilvC leuA leuA leuB leuB leuC leuC leuD leuD GCA_001418025_00013 GCA_001418025_00013 serS serS metE metE GCA_001418025_02519 GCA_001418025_02519 GCA_001418025_02491 GCA_001418025_02491 GCA_001418025_02454 GCA_001418025_02454 acpS acpS Ga0061060_1229 Ga0061060_1229 mtnN mtnN Ga0061060_1214 Ga0061060_1214 carB-2 carB-2 carA-2 carA-2 Ga0061060_1205 Ga0061060_1205 GCA_001418025_02332 GCA_001418025_02332 GCA_001418025_02306 GCA_001418025_02306 trpE-2 trpE-2 Ga0061060_1197 Ga0061060_1197 Ga0061060_1196 Ga0061060_1196 Ga0061060_1195 Ga0061060_1195
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
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aroCUnannotated protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (389 aa)
Ga0061060_1194Unannotated protein. (178 aa)
nadAUnannotated protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (367 aa)
pheAUnannotated protein. (287 aa)
GCA_001418025_02228Unannotated protein. (374 aa)
cysHUnannotated protein; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (235 aa)
hisZUnannotated protein; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (392 aa)
hisGUnannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (214 aa)
hisDUnannotated protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (425 aa)
hisBUnannotated protein. (194 aa)
hisHUnannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (210 aa)
hisAUnannotated protein. (242 aa)
hisFUnannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa)
hisIUnannotated protein; In the N-terminal section; belongs to the PRA-CH family. (207 aa)
GCA_001418025_02126Unannotated protein. (433 aa)
GCA_001418025_02105Unannotated protein; Belongs to the aspartokinase family. (448 aa)
rocA-2Unannotated protein; Belongs to the aldehyde dehydrogenase family. RocA subfamily. (516 aa)
proB-2Unannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (372 aa)
proA-2Unannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (413 aa)
GCA_001418025_02022Unannotated protein; Belongs to the TPP enzyme family. (541 aa)
ilvDUnannotated protein; Belongs to the IlvD/Edd family. (555 aa)
GCA_001418025_02013Unannotated protein. (486 aa)
GCA_001418025_02012Unannotated protein. (1514 aa)
Ga0061060_1136Unannotated protein. (276 aa)
ilvAUnannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (422 aa)
GCA_001418025_01939Unannotated protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (162 aa)
metAAUnannotated protein; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (302 aa)
Ga0061060_1121Unannotated protein. (268 aa)
lipAUnannotated protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (294 aa)
GCA_001418025_01784Unannotated protein. (433 aa)
GCA_001418025_01783Unannotated protein; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (352 aa)
thrBUnannotated protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (304 aa)
dapFUnannotated protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (284 aa)
GCA_001418025_01743Unannotated protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (590 aa)
cysIUnannotated protein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (571 aa)
GCA_001418025_01696Unannotated protein. (216 aa)
GCA_001418025_01685Unannotated protein; Belongs to the cysteine synthase/cystathionine beta- synthase family. (305 aa)
GCA_001418025_01682Unannotated protein. (237 aa)
GCA_001418025_01651Unannotated protein. (444 aa)
GCA_001418025_01626Unannotated protein; Belongs to the glutamine synthetase family. (453 aa)
GCA_001418025_01617Unannotated protein. (402 aa)
bioBUnannotated protein; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (329 aa)
GCA_001418025_01566Unannotated protein. (253 aa)
GCA_001418025_01556Unannotated protein. (443 aa)
trpB-2Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (387 aa)
proBUnannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (373 aa)
proAUnannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (413 aa)
fapRUnannotated protein; Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism. (194 aa)
plsXUnannotated protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (329 aa)
GCA_001418025_01453Unannotated protein. (313 aa)
acpPUnannotated protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (78 aa)
asdUnannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (349 aa)
GCA_001418025_01362Unannotated protein; Belongs to the aspartokinase family. (409 aa)
Ga0061060_1073Unannotated protein. (371 aa)
aroEUnannotated protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (275 aa)
proC-2Unannotated protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (276 aa)
aroKUnannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (168 aa)
lipMUnannotated protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation. (278 aa)
aroQUnannotated protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (148 aa)
GCA_001418025_01149Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (166 aa)
GCA_001418025_01148Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
folDUnannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa)
argRUnannotated protein; Regulates arginine biosynthesis genes. (149 aa)
proCUnannotated protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (273 aa)
Ga0061060_1062Unannotated protein. (68 aa)
lipLUnannotated protein; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family. (274 aa)
glyAUnannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (411 aa)
fabZUnannotated protein; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (143 aa)
lysAUnannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (437 aa)
GCA_001418025_00844Unannotated protein; Belongs to the PHP hydrolase family. HisK subfamily. (270 aa)
GCA_001418025_00843Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (524 aa)
bioDUnannotated protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (222 aa)
bioAUnannotated protein; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (450 aa)
aroBUnannotated protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (379 aa)
GCA_001418025_00798Unannotated protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (126 aa)
trpEUnannotated protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (501 aa)
trpDUnannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (336 aa)
trpCUnannotated protein; Belongs to the TrpC family. (253 aa)
trpFUnannotated protein; Belongs to the TrpF family. (211 aa)
trpBUnannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (398 aa)
trpAUnannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (279 aa)
hisCUnannotated protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (371 aa)
GCA_001418025_00790Unannotated protein. (367 aa)
aroAUnannotated protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (428 aa)
dapBUnannotated protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (264 aa)
GCA_001418025_00776Unannotated protein. (233 aa)
panBUnannotated protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (278 aa)
panCUnannotated protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (282 aa)
panDUnannotated protein; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (127 aa)
GCA_001418025_00738Unannotated protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (389 aa)
bioCUnannotated protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (255 aa)
GCA_001418025_00709Unannotated protein. (423 aa)
GCA_001418025_00703Unannotated protein. (258 aa)
GCA_001418025_00674Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (413 aa)
fabHUnannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (310 aa)
GCA_001418025_00667Unannotated protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (314 aa)
carBUnannotated protein. (1034 aa)
carAUnannotated protein; Belongs to the CarA family. (355 aa)
argDUnannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (385 aa)
argBUnannotated protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (252 aa)
argJUnannotated protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (406 aa)
argCUnannotated protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (341 aa)
GCA_001418025_00646Unannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1129 aa)
GCA_001418025_00610Unannotated protein. (616 aa)
rocDUnannotated protein; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (396 aa)
GCA_001418025_00558Unannotated protein. (391 aa)
serCUnannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (358 aa)
mtnAUnannotated protein; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily. (344 aa)
mtnKUnannotated protein; Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate. (389 aa)
mtnWUnannotated protein; Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P); Belongs to the RuBisCO large chain family. Type IV subfamily. (407 aa)
mtnXUnannotated protein; Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene). (218 aa)
mtnBUnannotated protein; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (202 aa)
mtnDUnannotated protein; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (178 aa)
dapHUnannotated protein; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (235 aa)
GCA_001418025_00300Unannotated protein; Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate. (378 aa)
menFUnannotated protein; Catalyzes the conversion of chorismate to isochorismate. (451 aa)
GCA_001418025_00205Unannotated protein. (629 aa)
GCA_001418025_00147Unannotated protein; Belongs to the PHP hydrolase family. HisK subfamily. (262 aa)
argGUnannotated protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (402 aa)
argHUnannotated protein. (458 aa)
GCA_001418025_00122Unannotated protein. (253 aa)
accDUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa)
accAUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (325 aa)
ilvEUnannotated protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (300 aa)
GCA_001418025_00030Unannotated protein. (572 aa)
GCA_001418025_00029Unannotated protein. (173 aa)
ilvCUnannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (341 aa)
leuAUnannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (514 aa)
leuBUnannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (369 aa)
leuCUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (472 aa)
leuDUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (194 aa)
GCA_001418025_00013Unannotated protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (249 aa)
serSUnannotated protein; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (424 aa)
metEUnannotated protein; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (757 aa)
GCA_001418025_02519Unannotated protein. (1507 aa)
GCA_001418025_02491Unannotated protein. (221 aa)
GCA_001418025_02454Unannotated protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (385 aa)
acpSUnannotated protein; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (120 aa)
Ga0061060_1229Unannotated protein. (453 aa)
mtnNUnannotated protein; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (232 aa)
Ga0061060_1214Unannotated protein. (307 aa)
carB-2Unannotated protein; Belongs to the CarB family. (1063 aa)
carA-2Unannotated protein; Belongs to the CarA family. (364 aa)
Ga0061060_1205Unannotated protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (297 aa)
GCA_001418025_02332Unannotated protein. (126 aa)
GCA_001418025_02306Unannotated protein; Belongs to the cysteine synthase/cystathionine beta- synthase family. (308 aa)
trpE-2Unannotated protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (474 aa)
Ga0061060_1197Unannotated protein. (289 aa)
Ga0061060_1196Unannotated protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (278 aa)
Ga0061060_1195Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa)
Your Current Organism:
Anoxybacillus suryakundensis
NCBI taxonomy Id: 1325335
Other names: A. suryakundensis, Anoxybacillus sp. JS1, Anoxybacillus sp. JS11, Anoxybacillus sp. JS15, Anoxybacillus sp. JS5, DSM 27374, JCM19211, LMG 27616, LMG:27616, strain JS1
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