STRINGSTRING
L486_08213 L486_08213 L486_08249 L486_08249 L486_07803 L486_07803 L486_07595 L486_07595 L486_07664 L486_07664 L486_07200 L486_07200 L486_07172 L486_07172 L486_07382 L486_07382 L486_06818 L486_06818 L486_07365 L486_07365 L486_06891 L486_06891 L486_07273 L486_07273 L486_07272 L486_07272 L486_07393 L486_07393 L486_07141 L486_07141 L486_06897 L486_06897 L486_07051 L486_07051 L486_07077 L486_07077 L486_06538 L486_06538 L486_07128 L486_07128 L486_06604 L486_06604 L486_07078 L486_07078 L486_06675 L486_06675 L486_06435 L486_06435 L486_06674 L486_06674 L486_06542 L486_06542 L486_06583 L486_06583 L486_06710 L486_06710 L486_06199 L486_06199 L486_06361 L486_06361 L486_06225 L486_06225 L486_05396 L486_05396 L486_05411 L486_05411 L486_05660 L486_05660 L486_05677 L486_05677 L486_05738 L486_05738 L486_05809 L486_05809 L486_05889 L486_05889 L486_05907 L486_05907 L486_04674 L486_04674 L486_05959 L486_05959 L486_04757 L486_04757 L486_04839 L486_04839 L486_04750 L486_04750 L486_04987 L486_04987 L486_04868 L486_04868 L486_04989 L486_04989 L486_05214 L486_05214 L486_05094 L486_05094 L486_03912 L486_03912 L486_03966 L486_03966 L486_04337 L486_04337 L486_04369 L486_04369 L486_04385 L486_04385 L486_04585 L486_04585 L486_03176 L486_03176 L486_03292 L486_03292 L486_03328 L486_03328 L486_03631 L486_03631 L486_03741 L486_03741 L486_03795 L486_03795 L486_02199 L486_02199 L486_02194 L486_02194 L486_02349 L486_02349 L486_02365 L486_02365 L486_02431 L486_02431 L486_02435 L486_02435 L486_02484 L486_02484 L486_02551 L486_02551 L486_02602 L486_02602 L486_02778 L486_02778 L486_02921 L486_02921 L486_02978 L486_02978 L486_00106 L486_00106 L486_00139 L486_00139 L486_00247 L486_00247 L486_00312 L486_00312 L486_00396 L486_00396 SLX1 SLX1 L486_00418 L486_00418 L486_00671 L486_00671 L486_00628 L486_00628 L486_00668 L486_00668 L486_01255 L486_01255 L486_01390 L486_01390 L486_01357 L486_01357 L486_01441 L486_01441 L486_01475 L486_01475 L486_01478 L486_01478 L486_01815 L486_01815 L486_01875 L486_01875 L486_01969 L486_01969
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
L486_08213CBFD_NFYB_HMF domain-containing protein. (212 aa)
L486_08249Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1016 aa)
L486_07803DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (344 aa)
L486_07595DNA repair and recombination protein RAD54-like protein. (817 aa)
L486_07664Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (613 aa)
L486_07200Uncharacterized protein. (841 aa)
L486_07172Uncharacterized protein. (177 aa)
L486_07382ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (956 aa)
L486_06818DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (725 aa)
L486_07365Uncharacterized protein. (879 aa)
L486_06891Uncharacterized protein. (1007 aa)
L486_07273DNA polymerase delta subunit 2. (506 aa)
L486_07272Uncharacterized protein. (549 aa)
L486_07393Uncharacterized protein. (900 aa)
L486_07141Galactinol synthase. (366 aa)
L486_06897Cir_N domain-containing protein. (338 aa)
L486_07051DNA repair and recombination protein RAD54B. (1082 aa)
L486_07077Uncharacterized protein. (1173 aa)
L486_06538ERCC4 domain-containing protein. (836 aa)
L486_07128Rad51 domain-containing protein. (369 aa)
L486_06604Uncharacterized protein. (768 aa)
L486_07078Uncharacterized protein. (76 aa)
L486_066753'-5' exonuclease domain-containing protein. (643 aa)
L486_06435DNA polymerase. (1969 aa)
L486_066743'-5' exonuclease domain-containing protein. (354 aa)
L486_06542BRCT domain-containing protein. (287 aa)
L486_06583Replication factor C subunit 3/5. (356 aa)
L486_06710Uncharacterized protein. (341 aa)
L486_06199Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (330 aa)
L486_06361Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (3049 aa)
L486_06225DNA excision repair protein ERCC-1. (384 aa)
L486_05396Replication factor C subunit 2/4. (365 aa)
L486_05411Chromosome transmission fidelity protein 18. (883 aa)
L486_05660Mitotic spindle assembly checkpoint protein MAD2B. (242 aa)
L486_05677DNA repair protein RAD50. (1360 aa)
L486_05738Uncharacterized protein. (492 aa)
L486_05809Replication factor C subunit 3/5. (372 aa)
L486_05889Uncharacterized protein. (1073 aa)
L486_05907Sister chromatid cohesion protein DCC1. (414 aa)
L486_04674Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2240 aa)
L486_05959Replication factor A2. (279 aa)
L486_04757DNA replication ATP-dependent helicase Dna2. (1348 aa)
L486_04839DNA mismatch repair protein MLH1. (761 aa)
L486_04750DNA polymerase eta subunit. (743 aa)
L486_04987DUF1767 domain-containing protein. (565 aa)
L486_04868Peroxisomal membrane protein PEX16. (381 aa)
L486_04989Replication factor C subunit 2/4. (350 aa)
L486_05214DNA repair protein. (329 aa)
L486_05094Uncharacterized protein. (263 aa)
L486_03912DNA helicase II/ATP-dependent DNA helicase PcrA. (1078 aa)
L486_03966DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1202 aa)
L486_04337DNA excision repair protein ERCC-4. (1129 aa)
L486_04369DNA repair protein rad18. (383 aa)
L486_04385DUF1996 domain-containing protein. (579 aa)
L486_04585DNA mismatch repair protein MSH2; Component of the post-replicative DNA mismatch repair system (MMR). (973 aa)
L486_03176DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (510 aa)
L486_03292Uncharacterized protein. (610 aa)
L486_03328DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (973 aa)
L486_03631ATPase. (572 aa)
L486_03741Uncharacterized protein. (1289 aa)
L486_03795DNA polymerase. (1496 aa)
L486_02199DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2244 aa)
L486_02194Replication factor C subunit 1. (1023 aa)
L486_02349DNA polymerase. (1058 aa)
L486_02365DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (1053 aa)
L486_02431BRCT domain-containing protein. (902 aa)
L486_02435RECA_2 domain-containing protein. (590 aa)
L486_02484CAMK protein kinase. (733 aa)
L486_02551Checkpoint protein; Belongs to the HUS1 family. (307 aa)
L486_02602DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1242 aa)
L486_02778Uncharacterized protein. (250 aa)
L486_02921DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1129 aa)
L486_02978DNA polymerase epsilon subunit B. (626 aa)
L486_00106AAA domain-containing protein. (1051 aa)
L486_00139DNA repair protein RAD5. (1197 aa)
L486_00247Uncharacterized protein. (1312 aa)
L486_00312DNA excision repair protein ERCC-5. (1335 aa)
L486_00396Rad51 domain-containing protein. (411 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (435 aa)
L486_00418DNA_MISMATCH_REPAIR_2 domain-containing protein. (821 aa)
L486_00671DNA polymerase kappa subunit. (633 aa)
L486_00628zf-4CXXC_R1 domain-containing protein. (918 aa)
L486_00668zf-GRF domain-containing protein. (265 aa)
L486_01255Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (171 aa)
L486_01390Uncharacterized protein. (676 aa)
L486_01357Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (703 aa)
L486_01441Asparagine-tRNA ligase. (606 aa)
L486_01475CAMK/CAMKL/CHK1 protein kinase; Belongs to the protein kinase superfamily. (453 aa)
L486_01478DNA cross-link repair 1A protein. (847 aa)
L486_01815DNA primase; Belongs to the eukaryotic-type primase small subunit family. (432 aa)
L486_01875Uncharacterized protein. (996 aa)
L486_01969Uncharacterized protein. (816 aa)
Your Current Organism:
Kwoniella mangroviensis
NCBI taxonomy Id: 1331196
Other names: K. mangroviensis CBS 10435, Kwoniella mangroviensis CBS 10435, Kwoniella mangroviensis CBS10435
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