28 items (Kwoniella mangroviensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	L486_06211	Uncharacterized protein. (1474 aa)
	L486_06538	ERCC4 domain-containing protein. (836 aa)
	L486_07882	CDC7 protein kinase. (915 aa)
	L486_08088	Uncharacterized protein. (618 aa)
	L486_08418	TP6A_N domain-containing protein. (755 aa)
	L486_07128	Rad51 domain-containing protein. (369 aa)
	L486_07051	DNA repair and recombination protein RAD54B. (1082 aa)
	L486_07664	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (613 aa)
	L486_07595	DNA repair and recombination protein RAD54-like protein. (817 aa)
	L486_07803	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (344 aa)
	L486_07706	Meiotic recombinase Dmc1; Belongs to the RecA family. (350 aa)
	L486_01784	Meiotic Sister-Chromatid recombination aldehyde dehydrogenase. (632 aa)
	L486_01742	RING-type domain-containing protein. (459 aa)
	L486_00753	Uncharacterized protein. (985 aa)
	L486_00394	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1492 aa)
	L486_00418	DNA_MISMATCH_REPAIR_2 domain-containing protein. (821 aa)
	L486_00396	Rad51 domain-containing protein. (411 aa)
	L486_02577	PLK/PLK1 protein kinase. (773 aa)
	L486_02487	Uncharacterized protein. (358 aa)
	L486_02384	TBPIP domain-containing protein. (283 aa)
	L486_02298	AAA domain-containing protein; Belongs to the AAA ATPase family. (560 aa)
	L486_02231	ERCC4 domain-containing protein. (598 aa)
	L486_02061	Meiotic nuclear division protein 1; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (171 aa)
	L486_03328	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (973 aa)
	L486_04337	DNA excision repair protein ERCC-4. (1129 aa)
	L486_04987	DUF1767 domain-containing protein. (565 aa)
	L486_04839	DNA mismatch repair protein MLH1. (761 aa)
	L486_04632	Uncharacterized protein. (1321 aa)

Your Current Organism:

Kwoniella mangroviensis

NCBI taxonomy Id: 1331196
Other names: K. mangroviensis CBS 10435, Kwoniella mangroviensis CBS 10435, Kwoniella mangroviensis CBS10435

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L486_00394	L486_02298	A0A1B9IZB6	A0A1B9IVT0	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.451
L486_00394	L486_02577	A0A1B9IZB6	A0A1B9IWU8	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	PLK/PLK1 protein kinase.	0.557
L486_00394	L486_03328	A0A1B9IZB6	A0A1B9ITH4	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.541
L486_00394	L486_04632	A0A1B9IZB6	A0A1B9INR5	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Uncharacterized protein.	0.440
L486_00394	L486_06211	A0A1B9IZB6	A0A1B9ILK9	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	Uncharacterized protein.	0.610
L486_00394	L486_06538	A0A1B9IZB6	A0A1B9IJG4	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	ERCC4 domain-containing protein.	0.413
L486_00394	L486_07051	A0A1B9IZB6	A0A1B9IJB5	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	DNA repair and recombination protein RAD54B.	0.459
L486_00394	L486_07595	A0A1B9IZB6	A0A1B9IGX8	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	DNA repair and recombination protein RAD54-like protein.	0.459
L486_00394	L486_07803	A0A1B9IZB6	A0A1B9IGV2	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.611
L486_00394	L486_08418	A0A1B9IZB6	A0A1B9IEX8	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.	TP6A_N domain-containing protein.	0.522
L486_00396	L486_00418	A0A1B9IYZ8	A0A1B9IZ20	Rad51 domain-containing protein.	DNA_MISMATCH_REPAIR_2 domain-containing protein.	0.621
L486_00396	L486_02061	A0A1B9IYZ8	A0A1B9IV37	Rad51 domain-containing protein.	Meiotic nuclear division protein 1; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family.	0.527
L486_00396	L486_02298	A0A1B9IYZ8	A0A1B9IVT0	Rad51 domain-containing protein.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.604
L486_00396	L486_02384	A0A1B9IYZ8	A0A1B9IW09	Rad51 domain-containing protein.	TBPIP domain-containing protein.	0.520
L486_00396	L486_02577	A0A1B9IYZ8	A0A1B9IWU8	Rad51 domain-containing protein.	PLK/PLK1 protein kinase.	0.444
L486_00396	L486_03328	A0A1B9IYZ8	A0A1B9ITH4	Rad51 domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.835
L486_00396	L486_04337	A0A1B9IYZ8	A0A1B9IRY6	Rad51 domain-containing protein.	DNA excision repair protein ERCC-4.	0.794
L486_00396	L486_04839	A0A1B9IYZ8	A0A1B9IPF5	Rad51 domain-containing protein.	DNA mismatch repair protein MLH1.	0.643
L486_00396	L486_04987	A0A1B9IYZ8	A0A1B9IPP8	Rad51 domain-containing protein.	DUF1767 domain-containing protein.	0.806
L486_00396	L486_06211	A0A1B9IYZ8	A0A1B9ILK9	Rad51 domain-containing protein.	Uncharacterized protein.	0.939