(17 nodes) Establishment of cell polarity network (Kwoniella mangroviensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	L486_01629	Uncharacterized protein. (1080 aa)
	L486_08425	Uncharacterized protein. (428 aa)
	L486_07714	Uncharacterized protein. (182 aa)
	L486_07494	Dynactin 1. (1346 aa)
	PAC1	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein- mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck. (447 aa)
	L486_07619	SH3 domain-containing protein. (1486 aa)
	L486_07546	UDENN domain-containing protein. (885 aa)
	L486_06337	Uncharacterized protein. (1123 aa)
	L486_05815	CAP-Gly domain-containing protein. (1035 aa)
	L486_04981	Ras-GAP domain-containing protein. (1001 aa)
	L486_02131	Cell division control protein 42. (191 aa)
	L486_02224	Uncharacterized protein. (1081 aa)
	L486_02625	AIP3 domain-containing protein. (1159 aa)
	L486_00814	Cell division control protein 24. (1115 aa)
	L486_00979	NUDE_C domain-containing protein. (779 aa)
	L486_01233	ADP-ribosylation factor 3; Belongs to the small GTPase superfamily. Arf family. (158 aa)
	L486_01351	WD_REPEATS_REGION domain-containing protein. (1298 aa)

Your Current Organism:

Kwoniella mangroviensis

NCBI taxonomy Id: 1331196
Other names: K. mangroviensis CBS 10435, Kwoniella mangroviensis CBS 10435, Kwoniella mangroviensis CBS10435

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L486_00814	L486_01233	A0A1B9J055	A0A1B9J1C8	Cell division control protein 24.	ADP-ribosylation factor 3; Belongs to the small GTPase superfamily. Arf family.	0.674
L486_00814	L486_02131	A0A1B9J055	A0A1B9IVC0	Cell division control protein 24.	Cell division control protein 42.	0.988
L486_00814	L486_02625	A0A1B9J055	A0A1B9IWR1	Cell division control protein 24.	AIP3 domain-containing protein.	0.479
L486_00814	L486_04981	A0A1B9J055	A0A1B9IPM4	Cell division control protein 24.	Ras-GAP domain-containing protein.	0.416
L486_00979	PAC1	A0A1B9J0L5	A0A1B9IH05	NUDE_C domain-containing protein.	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein- mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.	0.947
L486_01233	L486_00814	A0A1B9J1C8	A0A1B9J055	ADP-ribosylation factor 3; Belongs to the small GTPase superfamily. Arf family.	Cell division control protein 24.	0.674
L486_01233	L486_02131	A0A1B9J1C8	A0A1B9IVC0	ADP-ribosylation factor 3; Belongs to the small GTPase superfamily. Arf family.	Cell division control protein 42.	0.638
L486_01233	L486_04981	A0A1B9J1C8	A0A1B9IPM4	ADP-ribosylation factor 3; Belongs to the small GTPase superfamily. Arf family.	Ras-GAP domain-containing protein.	0.710
L486_01233	L486_05815	A0A1B9J1C8	A0A1B9IN09	ADP-ribosylation factor 3; Belongs to the small GTPase superfamily. Arf family.	CAP-Gly domain-containing protein.	0.447
L486_01233	L486_07494	A0A1B9J1C8	A0A1B9IGM4	ADP-ribosylation factor 3; Belongs to the small GTPase superfamily. Arf family.	Dynactin 1.	0.447
L486_01233	PAC1	A0A1B9J1C8	A0A1B9IH05	ADP-ribosylation factor 3; Belongs to the small GTPase superfamily. Arf family.	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein- mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.	0.585
L486_01629	L486_07619	A0A1B9J2E8	A0A1B9IHK8	Uncharacterized protein.	SH3 domain-containing protein.	0.435
L486_02131	L486_00814	A0A1B9IVC0	A0A1B9J055	Cell division control protein 42.	Cell division control protein 24.	0.988
L486_02131	L486_01233	A0A1B9IVC0	A0A1B9J1C8	Cell division control protein 42.	ADP-ribosylation factor 3; Belongs to the small GTPase superfamily. Arf family.	0.638
L486_02131	L486_02224	A0A1B9IVC0	A0A1B9IVK6	Cell division control protein 42.	Uncharacterized protein.	0.672
L486_02131	L486_02625	A0A1B9IVC0	A0A1B9IWR1	Cell division control protein 42.	AIP3 domain-containing protein.	0.584
L486_02131	L486_04981	A0A1B9IVC0	A0A1B9IPM4	Cell division control protein 42.	Ras-GAP domain-containing protein.	0.766
L486_02131	L486_07619	A0A1B9IVC0	A0A1B9IHK8	Cell division control protein 42.	SH3 domain-containing protein.	0.598
L486_02131	L486_07714	A0A1B9IVC0	A0A1B9IGF3	Cell division control protein 42.	Uncharacterized protein.	0.556
L486_02131	PAC1	A0A1B9IVC0	A0A1B9IH05	Cell division control protein 42.	Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein- mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.	0.535