Your Input: | |||||
L486_05951 | Chromatin modification-related protein. (350 aa) | ||||
L486_05709 | Uncharacterized protein. (111 aa) | ||||
L486_05879 | CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily. (358 aa) | ||||
L486_05669 | RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (492 aa) | ||||
L486_05783 | Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (159 aa) | ||||
L486_05680 | Geranylgeranyl transferase type-2 subunit alpha. (378 aa) | ||||
L486_05462 | B-block_TFIIIC domain-containing protein. (471 aa) | ||||
L486_05693 | Enhancer of polycomb-like protein. (1056 aa) | ||||
L486_05495 | Uncharacterized protein. (734 aa) | ||||
L486_05400 | RNA polymerase II transcription factor. (671 aa) | ||||
L486_05463 | Uncharacterized protein. (2040 aa) | ||||
L486_05603 | PHD-type domain-containing protein. (1125 aa) | ||||
L486_05442 | Tuberin. (1964 aa) | ||||
L486_05547 | Nitrite reductase [NAD(P)H], large subunit. (1102 aa) | ||||
L486_05527 | Uncharacterized protein. (762 aa) | ||||
MED4 | Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (251 aa) | ||||
L486_05507 | tRNA_int_endo domain-containing protein. (528 aa) | ||||
L486_05438 | Cytochrome c oxidase subunit 6a. (88 aa) | ||||
L486_05540 | AGC/PDK1 protein kinase. (1175 aa) | ||||
L486_05407 | Kexin; Belongs to the peptidase S8 family. (902 aa) | ||||
L486_05510 | Uncharacterized protein. (583 aa) | ||||
L486_05454 | Uncharacterized protein. (131 aa) | ||||
L486_05423 | CCR4-NOT transcription complex subunit 1. (2284 aa) | ||||
L486_05448 | Paired amphipathic helix protein Sin3a. (1299 aa) | ||||
L486_05405 | Pre-mRNA-processing protein 45. (579 aa) | ||||
L486_05385 | Uncharacterized protein. (522 aa) | ||||
L486_06367 | TPR_REGION domain-containing protein. (388 aa) | ||||
L486_06356 | Cell differentiation protein rcd1. (478 aa) | ||||
L486_06021 | Transcription elongation factor S-II. (343 aa) | ||||
L486_06015 | Sterility protein Ste20. (1488 aa) | ||||
L486_06074 | Cyclin N-terminal domain-containing protein. (377 aa) | ||||
L486_06239 | Transcriptional activator HAP5. (283 aa) | ||||
L486_06207 | CMGC/CDK/CDK8 protein kinase. (482 aa) | ||||
L486_06028 | Cytochrome c oxidase subunit 6b. (108 aa) | ||||
L486_06008 | Uncharacterized protein. (439 aa) | ||||
L486_06670 | Brg1-associated factor b; Belongs to the actin family. (474 aa) | ||||
L486_06802 | Bac_luciferase domain-containing protein. (385 aa) | ||||
L486_06037 | CDK-activating kinase assembly factor MAT1. (375 aa) | ||||
L486_06674 | 3'-5' exonuclease domain-containing protein. (354 aa) | ||||
L486_06803 | PKS_ER domain-containing protein. (457 aa) | ||||
L486_06570 | Pyr_redox_2 domain-containing protein. (447 aa) | ||||
L486_06524 | CCR4-NOT transcription complex subunit 4. (877 aa) | ||||
L486_07125 | Serine/threonine protein kinase. (977 aa) | ||||
L486_06547 | Uncharacterized protein. (556 aa) | ||||
L486_06675 | 3'-5' exonuclease domain-containing protein. (643 aa) | ||||
L486_06526 | Cytochrome c oxidase subunit 5a. (139 aa) | ||||
L486_07078 | Uncharacterized protein. (76 aa) | ||||
L486_06644 | Cytochrome c oxidase assembly protein subunit 11. (323 aa) | ||||
L486_07054 | Uncharacterized protein. (477 aa) | ||||
L486_06548 | Glucose-6-phosphate isomerase; Belongs to the GPI family. (557 aa) | ||||
L486_07102 | Thioredoxin; Belongs to the thioredoxin family. (104 aa) | ||||
L486_06423 | Uncharacterized protein. (474 aa) | ||||
L486_07077 | Uncharacterized protein. (1173 aa) | ||||
L486_06531 | Uncharacterized protein. (273 aa) | ||||
L486_06914 | CCR4-NOT transcription complex subunit 2. (449 aa) | ||||
L486_06429 | Bromo domain-containing protein. (833 aa) | ||||
L486_07080 | Pyr_redox_2 domain-containing protein. (413 aa) | ||||
L486_06956 | Peptidyl-prolyl cis-trans isomerase. (180 aa) | ||||
L486_06890 | STE/STE7/MEK1 protein kinase. (495 aa) | ||||
L486_07082 | Uncharacterized protein. (433 aa) | ||||
L486_07393 | Uncharacterized protein. (900 aa) | ||||
L486_06922 | FACT complex subunit SPT16. (1045 aa) | ||||
L486_06912 | Flavoprotein. (551 aa) | ||||
L486_07300 | Uncharacterized protein. (451 aa) | ||||
L486_07451 | Enoyl reductase. (360 aa) | ||||
L486_06871 | Bromo domain-containing protein. (985 aa) | ||||
L486_07194 | PKS_ER domain-containing protein. (345 aa) | ||||
L486_07160 | SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (312 aa) | ||||
L486_07198 | Uncharacterized protein. (533 aa) | ||||
L486_07630 | SAP domain-containing protein. (376 aa) | ||||
L486_07382 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (956 aa) | ||||
L486_07526 | Mitochondrial protein. (309 aa) | ||||
L486_07926 | DNA excision repair protein ERCC-3. (876 aa) | ||||
L486_07209 | Histone H2B; Belongs to the histone H2B family. (139 aa) | ||||
L486_07591 | Polyubiquitin. (160 aa) | ||||
L486_07900 | Uncharacterized protein. (793 aa) | ||||
L486_07561 | Uncharacterized protein. (951 aa) | ||||
L486_07664 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (613 aa) | ||||
L486_07488 | Uncharacterized protein. (1430 aa) | ||||
L486_07615 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1253 aa) | ||||
L486_07594 | Uncharacterized protein. (269 aa) | ||||
L486_07799 | Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1145 aa) | ||||
L486_07584 | Transcription activator. (299 aa) | ||||
L486_07899 | Histone deacetylase HOS3. (816 aa) | ||||
L486_08112 | Uncharacterized protein. (1202 aa) | ||||
L486_07737 | DNA-directed RNA polymerase II subunit RPB4. (163 aa) | ||||
L486_08085 | Anti_prolifrtn domain-containing protein. (556 aa) | ||||
L486_07760 | Uncharacterized protein. (894 aa) | ||||
L486_08052 | CMGC/CK2 protein kinase; Belongs to the protein kinase superfamily. (353 aa) | ||||
L486_07960 | Uncharacterized protein. (173 aa) | ||||
L486_08004 | HAL protein kinase. (760 aa) | ||||
L486_08228 | Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (228 aa) | ||||
L486_08325 | Zf-rbx1 domain-containing protein. (91 aa) | ||||
L486_07977 | RING-type domain-containing protein. (351 aa) | ||||
L486_08210 | G protein beta subunit-like protein. (339 aa) | ||||
L486_08358 | DNA-directed RNA polymerase II subunit RPB11. (161 aa) | ||||
L486_08427 | GATA-type domain-containing protein. (674 aa) | ||||
L486_08454 | Uncharacterized protein. (866 aa) | ||||
L486_08192 | Uncharacterized protein. (383 aa) | ||||
L486_03207 | Uncharacterized protein. (803 aa) | ||||
L486_03228 | Uncharacterized protein. (1001 aa) | ||||
L486_03061 | Uncharacterized protein. (579 aa) | ||||
L486_03102 | Uncharacterized protein. (558 aa) | ||||
L486_04559 | Uncharacterized protein. (1769 aa) | ||||
L486_04545 | DNA-directed RNA polymerase I, II, and III subunit RPABC1. (208 aa) | ||||
L486_04522 | STE/STE7 protein kinase. (601 aa) | ||||
L486_04440 | HAL protein kinase. (1025 aa) | ||||
L486_04349 | CUE domain-containing protein. (213 aa) | ||||
L486_04210 | Uncharacterized protein. (451 aa) | ||||
L486_04215 | Nucleolar complex protein 2. (738 aa) | ||||
L486_04057 | DNA excision repair protein ERCC-2. (806 aa) | ||||
L486_04152 | CMGC/CDK/CDK9 protein kinase. (1027 aa) | ||||
L486_04000 | Thioredoxin domain-containing protein. (303 aa) | ||||
L486_04132 | START domain-containing protein. (1624 aa) | ||||
L486_04034 | CTD kinase subunit beta. (386 aa) | ||||
L486_03950 | Tyrosine phosphatase. (770 aa) | ||||
L486_03972 | Rab proteins geranylgeranyltransferase; Belongs to the Rab GDI family. (511 aa) | ||||
L486_05229 | Prefoldin, alpha subunit. (149 aa) | ||||
L486_05291 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1130 aa) | ||||
L486_05284 | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (350 aa) | ||||
L486_05198 | Uncharacterized protein. (877 aa) | ||||
L486_05115 | Uncharacterized protein. (661 aa) | ||||
L486_05105 | Peroxiredoxin (Alkyl hydroperoxide reductase subunit C). (233 aa) | ||||
L486_05017 | Mitochondrial protein. (228 aa) | ||||
L486_04980 | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (498 aa) | ||||
L486_04987 | DUF1767 domain-containing protein. (565 aa) | ||||
L486_04909 | DNA-directed RNA polymerase II subunit RPB3. (383 aa) | ||||
L486_04789 | Uncharacterized protein. (693 aa) | ||||
L486_04782 | Uncharacterized protein. (148 aa) | ||||
L486_04749 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1804 aa) | ||||
L486_04606 | Zn(2)-C6 fungal-type domain-containing protein. (726 aa) | ||||
L486_04691 | Nuclear transcription factor Y subunit beta. (203 aa) | ||||
L486_04674 | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2240 aa) | ||||
L486_04654 | B30.2/SPRY domain-containing protein. (657 aa) | ||||
L486_05971 | Helicase ATP-binding domain-containing protein. (891 aa) | ||||
L486_05934 | Cytochrome c oxidase subunit 7c. (75 aa) | ||||
L486_01861 | SWIB domain-containing protein. (481 aa) | ||||
L486_01958 | Uncharacterized protein. (751 aa) | ||||
L486_01970 | Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (340 aa) | ||||
L486_01917 | Uncharacterized protein. (127 aa) | ||||
L486_01928 | Homeobox_KN domain-containing protein. (437 aa) | ||||
MDM34 | Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (844 aa) | ||||
L486_01588 | STE/STE7/MKK protein kinase. (648 aa) | ||||
L486_01702 | Uncharacterized protein. (750 aa) | ||||
L486_01642 | PA28_beta domain-containing protein. (275 aa) | ||||
L486_01605 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (479 aa) | ||||
L486_01597 | Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (256 aa) | ||||
L486_01556 | WD_REPEATS_REGION domain-containing protein. (583 aa) | ||||
L486_01510 | DNA-directed RNA polymerase I, II, and III subunit RPABC2. (153 aa) | ||||
L486_01493 | Uncharacterized protein. (668 aa) | ||||
L486_01475 | CAMK/CAMKL/CHK1 protein kinase; Belongs to the protein kinase superfamily. (453 aa) | ||||
L486_01433 | Uncharacterized protein. (195 aa) | ||||
L486_01308 | Mitochondrial protein. (180 aa) | ||||
L486_01253 | General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (440 aa) | ||||
L486_01280 | Cyclin H; Belongs to the cyclin family. (439 aa) | ||||
L486_01200 | Adenylate cyclase. (2382 aa) | ||||
L486_01129 | Uncharacterized protein. (374 aa) | ||||
L486_00926 | DNA-directed RNA polymerase I, II, and III subunit RPABC3. (163 aa) | ||||
L486_00887 | Uncharacterized protein. (389 aa) | ||||
L486_00821 | Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (115 aa) | ||||
L486_00668 | zf-GRF domain-containing protein. (265 aa) | ||||
L486_00770 | CMGC/CDK/CRK7 protein kinase. (1270 aa) | ||||
L486_00628 | zf-4CXXC_R1 domain-containing protein. (918 aa) | ||||
L486_00733 | RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (893 aa) | ||||
L486_00662 | Cytochrome c oxidase subunit 5b. (156 aa) | ||||
L486_00444 | Alcohol dehydrogenase. (358 aa) | ||||
L486_00537 | Transcription initiation factor TFIIH subunit 1. (658 aa) | ||||
L486_00552 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (123 aa) | ||||
L486_00524 | CCR4-NOT transcription complex subunit 7/8. (286 aa) | ||||
L486_00519 | Quinone oxidoreductase. (319 aa) | ||||
MED10 | Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (195 aa) | ||||
L486_00472 | PKS_ER domain-containing protein. (342 aa) | ||||
MED6 | Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (364 aa) | ||||
L486_00343 | Uncharacterized protein. (411 aa) | ||||
L486_00242 | Uncharacterized protein. (1251 aa) | ||||
L486_00155 | Transcription elongation factor B, polypeptide 1; Belongs to the SKP1 family. (104 aa) | ||||
L486_00156 | Uncharacterized protein. (248 aa) | ||||
L486_00090 | Chromo domain-containing protein. (744 aa) | ||||
L486_00062 | Alcohol dehydrogenase. (336 aa) | ||||
L486_00053 | TEA domain-containing protein. (466 aa) | ||||
L486_00013 | Uncharacterized protein. (1809 aa) | ||||
L486_02979 | Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2354 aa) | ||||
L486_02975 | CCR4-NOT transcription complex subunit 3. (665 aa) | ||||
L486_02915 | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (584 aa) | ||||
MED17 | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (625 aa) | ||||
L486_02771 | BHLH domain-containing protein. (449 aa) | ||||
L486_02741 | Cyclin C; Belongs to the cyclin family. (436 aa) | ||||
L486_02716 | 1-phosphatidylinositol-4-phosphate 5-kinase. (1017 aa) | ||||
L486_02577 | PLK/PLK1 protein kinase. (773 aa) | ||||
L486_02680 | Uncharacterized protein. (1558 aa) | ||||
L486_02623 | Polyubiquitin. (381 aa) | ||||
L486_02513 | Cytochrome c oxidase subunit 4. (161 aa) | ||||
L486_02484 | CAMK protein kinase. (733 aa) | ||||
L486_02493 | Phosphatidylinositol 3-kinase; Belongs to the PI3/PI4-kinase family. (1426 aa) | ||||
L486_02476 | Uncharacterized protein. (275 aa) | ||||
L486_02455 | DNA damage checkpoint protein rad24; Belongs to the 14-3-3 family. (258 aa) | ||||
L486_02449 | Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1262 aa) | ||||
L486_02409 | PHD-type domain-containing protein. (933 aa) | ||||
L486_02422 | BUD32 protein kinase. (305 aa) | ||||
L486_02405 | ATP-dependent helicase STH1/SNF2. (1540 aa) | ||||
L486_02401 | Uncharacterized protein. (938 aa) | ||||
L486_02378 | PRELI/MSF1 domain-containing protein. (302 aa) | ||||
L486_02221 | Uncharacterized protein. (804 aa) | ||||
L486_02281 | Uncharacterized protein. (728 aa) | ||||
L486_02119 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (213 aa) | ||||
L486_02184 | Chromatin modification-related protein. (485 aa) | ||||
L486_02143 | Uncharacterized protein. (646 aa) | ||||
L486_02040 | Pyr_redox_2 domain-containing protein. (451 aa) | ||||
L486_02038 | Uncharacterized protein. (110 aa) | ||||
L486_02045 | CIA30 domain-containing protein. (271 aa) | ||||
L486_03829 | Uncharacterized protein. (1472 aa) | ||||
L486_03760 | Uncharacterized protein. (242 aa) | ||||
L486_03756 | Uncharacterized protein. (563 aa) | ||||
L486_03772 | mRNA_triPase domain-containing protein. (323 aa) | ||||
L486_03738 | DNA-directed RNA polymerase I, II, and III subunit RPABC4. (74 aa) | ||||
L486_03744 | DNA-directed RNA polymerase II subunit RPB7. (172 aa) | ||||
L486_03671 | Uncharacterized protein. (211 aa) | ||||
L486_03593 | Uncharacterized protein. (853 aa) | ||||
L486_03487 | Uncharacterized protein. (219 aa) | ||||
L486_03442 | FAS1 domain-containing protein. (244 aa) | ||||
L486_03328 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (973 aa) | ||||
L486_03292 | Uncharacterized protein. (610 aa) | ||||
L486_03103 | GATA-type domain-containing protein. (514 aa) |