STRINGSTRING
L486_02040 L486_02040 L486_02045 L486_02045 L486_03760 L486_03760 L486_03738 L486_03738 L486_03744 L486_03744 L486_03593 L486_03593 L486_03487 L486_03487 L486_03328 L486_03328 L486_03292 L486_03292 L486_03207 L486_03207 L486_03061 L486_03061 L486_04545 L486_04545 L486_04522 L486_04522 L486_04440 L486_04440 L486_04349 L486_04349 L486_04210 L486_04210 L486_04215 L486_04215 L486_04057 L486_04057 L486_04152 L486_04152 L486_04000 L486_04000 L486_04034 L486_04034 L486_03950 L486_03950 L486_03972 L486_03972 L486_05291 L486_05291 L486_05284 L486_05284 L486_05198 L486_05198 L486_05115 L486_05115 L486_05105 L486_05105 L486_05017 L486_05017 L486_04980 L486_04980 L486_04987 L486_04987 L486_04909 L486_04909 L486_04749 L486_04749 L486_04606 L486_04606 L486_04674 L486_04674 L486_05971 L486_05971 L486_05951 L486_05951 L486_05934 L486_05934 L486_05709 L486_05709 L486_05879 L486_05879 L486_05669 L486_05669 L486_05680 L486_05680 L486_05462 L486_05462 L486_05463 L486_05463 L486_05442 L486_05442 L486_05547 L486_05547 L486_05527 L486_05527 L486_05438 L486_05438 L486_05540 L486_05540 L486_05454 L486_05454 L486_05423 L486_05423 L486_05385 L486_05385 L486_06367 L486_06367 L486_06356 L486_06356 L486_06021 L486_06021 L486_06015 L486_06015 L486_06074 L486_06074 L486_06028 L486_06028 L486_06008 L486_06008 L486_06802 L486_06802 L486_06037 L486_06037 L486_06674 L486_06674 L486_06803 L486_06803 L486_06570 L486_06570 L486_06524 L486_06524 L486_07125 L486_07125 L486_06547 L486_06547 L486_06675 L486_06675 L486_06526 L486_06526 L486_07078 L486_07078 L486_06644 L486_06644 L486_07054 L486_07054 L486_06548 L486_06548 L486_07102 L486_07102 L486_06423 L486_06423 L486_07077 L486_07077 L486_06914 L486_06914 L486_07080 L486_07080 L486_06956 L486_06956 L486_06890 L486_06890 L486_07082 L486_07082 L486_07393 L486_07393 L486_06922 L486_06922 L486_06912 L486_06912 L486_07300 L486_07300 L486_07451 L486_07451 L486_06871 L486_06871 L486_07194 L486_07194 L486_07160 L486_07160 L486_07630 L486_07630 L486_07382 L486_07382 L486_07526 L486_07526 L486_07926 L486_07926 L486_07591 L486_07591 L486_07664 L486_07664 L486_07615 L486_07615 L486_07799 L486_07799 L486_08112 L486_08112 L486_07737 L486_07737 L486_08085 L486_08085 L486_08052 L486_08052 L486_08004 L486_08004 L486_08210 L486_08210 L486_08358 L486_08358 L486_00519 L486_00519 L486_00472 L486_00472 L486_00343 L486_00343 L486_00242 L486_00242 L486_00155 L486_00155 L486_00156 L486_00156 L486_00090 L486_00090 L486_00062 L486_00062 L486_02979 L486_02979 L486_02975 L486_02975 L486_02915 L486_02915 L486_02716 L486_02716 L486_02577 L486_02577 L486_02623 L486_02623 L486_02513 L486_02513 L486_02484 L486_02484 L486_02493 L486_02493 L486_02476 L486_02476 L486_02455 L486_02455 L486_02422 L486_02422 L486_02401 L486_02401 L486_02378 L486_02378 L486_02281 L486_02281 L486_02119 L486_02119 L486_02184 L486_02184 L486_02143 L486_02143 L486_02038 L486_02038 L486_01970 L486_01970 L486_01917 L486_01917 MDM34 MDM34 L486_01588 L486_01588 L486_01702 L486_01702 L486_01605 L486_01605 L486_01597 L486_01597 L486_01510 L486_01510 L486_01475 L486_01475 L486_01308 L486_01308 L486_01253 L486_01253 L486_01280 L486_01280 L486_01200 L486_01200 L486_01129 L486_01129 L486_00926 L486_00926 L486_00821 L486_00821 L486_00668 L486_00668 L486_00770 L486_00770 L486_00628 L486_00628 L486_00733 L486_00733 L486_00662 L486_00662 L486_00444 L486_00444 L486_00537 L486_00537 L486_00552 L486_00552 L486_00524 L486_00524
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
L486_02040Pyr_redox_2 domain-containing protein. (451 aa)
L486_02045CIA30 domain-containing protein. (271 aa)
L486_03760Uncharacterized protein. (242 aa)
L486_03738DNA-directed RNA polymerase I, II, and III subunit RPABC4. (74 aa)
L486_03744DNA-directed RNA polymerase II subunit RPB7. (172 aa)
L486_03593Uncharacterized protein. (853 aa)
L486_03487Uncharacterized protein. (219 aa)
L486_03328DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (973 aa)
L486_03292Uncharacterized protein. (610 aa)
L486_03207Uncharacterized protein. (803 aa)
L486_03061Uncharacterized protein. (579 aa)
L486_04545DNA-directed RNA polymerase I, II, and III subunit RPABC1. (208 aa)
L486_04522STE/STE7 protein kinase. (601 aa)
L486_04440HAL protein kinase. (1025 aa)
L486_04349CUE domain-containing protein. (213 aa)
L486_04210Uncharacterized protein. (451 aa)
L486_04215Nucleolar complex protein 2. (738 aa)
L486_04057DNA excision repair protein ERCC-2. (806 aa)
L486_04152CMGC/CDK/CDK9 protein kinase. (1027 aa)
L486_04000Thioredoxin domain-containing protein. (303 aa)
L486_04034CTD kinase subunit beta. (386 aa)
L486_03950Tyrosine phosphatase. (770 aa)
L486_03972Rab proteins geranylgeranyltransferase; Belongs to the Rab GDI family. (511 aa)
L486_05291Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1130 aa)
L486_05284Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (350 aa)
L486_05198Uncharacterized protein. (877 aa)
L486_05115Uncharacterized protein. (661 aa)
L486_05105Peroxiredoxin (Alkyl hydroperoxide reductase subunit C). (233 aa)
L486_05017Mitochondrial protein. (228 aa)
L486_04980Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (498 aa)
L486_04987DUF1767 domain-containing protein. (565 aa)
L486_04909DNA-directed RNA polymerase II subunit RPB3. (383 aa)
L486_04749DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1804 aa)
L486_04606Zn(2)-C6 fungal-type domain-containing protein. (726 aa)
L486_04674Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2240 aa)
L486_05971Helicase ATP-binding domain-containing protein. (891 aa)
L486_05951Chromatin modification-related protein. (350 aa)
L486_05934Cytochrome c oxidase subunit 7c. (75 aa)
L486_05709Uncharacterized protein. (111 aa)
L486_05879CMGC/CDK/CDK7 protein kinase; Belongs to the protein kinase superfamily. (358 aa)
L486_05669RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (492 aa)
L486_05680Geranylgeranyl transferase type-2 subunit alpha. (378 aa)
L486_05462B-block_TFIIIC domain-containing protein. (471 aa)
L486_05463Uncharacterized protein. (2040 aa)
L486_05442Tuberin. (1964 aa)
L486_05547Nitrite reductase [NAD(P)H], large subunit. (1102 aa)
L486_05527Uncharacterized protein. (762 aa)
L486_05438Cytochrome c oxidase subunit 6a. (88 aa)
L486_05540AGC/PDK1 protein kinase. (1175 aa)
L486_05454Uncharacterized protein. (131 aa)
L486_05423CCR4-NOT transcription complex subunit 1. (2284 aa)
L486_05385Uncharacterized protein. (522 aa)
L486_06367TPR_REGION domain-containing protein. (388 aa)
L486_06356Cell differentiation protein rcd1. (478 aa)
L486_06021Transcription elongation factor S-II. (343 aa)
L486_06015Sterility protein Ste20. (1488 aa)
L486_06074Cyclin N-terminal domain-containing protein. (377 aa)
L486_06028Cytochrome c oxidase subunit 6b. (108 aa)
L486_06008Uncharacterized protein. (439 aa)
L486_06802Bac_luciferase domain-containing protein. (385 aa)
L486_06037CDK-activating kinase assembly factor MAT1. (375 aa)
L486_066743'-5' exonuclease domain-containing protein. (354 aa)
L486_06803PKS_ER domain-containing protein. (457 aa)
L486_06570Pyr_redox_2 domain-containing protein. (447 aa)
L486_06524CCR4-NOT transcription complex subunit 4. (877 aa)
L486_07125Serine/threonine protein kinase. (977 aa)
L486_06547Uncharacterized protein. (556 aa)
L486_066753'-5' exonuclease domain-containing protein. (643 aa)
L486_06526Cytochrome c oxidase subunit 5a. (139 aa)
L486_07078Uncharacterized protein. (76 aa)
L486_06644Cytochrome c oxidase assembly protein subunit 11. (323 aa)
L486_07054Uncharacterized protein. (477 aa)
L486_06548Glucose-6-phosphate isomerase; Belongs to the GPI family. (557 aa)
L486_07102Thioredoxin; Belongs to the thioredoxin family. (104 aa)
L486_06423Uncharacterized protein. (474 aa)
L486_07077Uncharacterized protein. (1173 aa)
L486_06914CCR4-NOT transcription complex subunit 2. (449 aa)
L486_07080Pyr_redox_2 domain-containing protein. (413 aa)
L486_06956Peptidyl-prolyl cis-trans isomerase. (180 aa)
L486_06890STE/STE7/MEK1 protein kinase. (495 aa)
L486_07082Uncharacterized protein. (433 aa)
L486_07393Uncharacterized protein. (900 aa)
L486_06922FACT complex subunit SPT16. (1045 aa)
L486_06912Flavoprotein. (551 aa)
L486_07300Uncharacterized protein. (451 aa)
L486_07451Enoyl reductase. (360 aa)
L486_06871Bromo domain-containing protein. (985 aa)
L486_07194PKS_ER domain-containing protein. (345 aa)
L486_07160SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (312 aa)
L486_07630SAP domain-containing protein. (376 aa)
L486_07382ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (956 aa)
L486_07526Mitochondrial protein. (309 aa)
L486_07926DNA excision repair protein ERCC-3. (876 aa)
L486_07591Polyubiquitin. (160 aa)
L486_07664Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (613 aa)
L486_07615DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1253 aa)
L486_07799Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1145 aa)
L486_08112Uncharacterized protein. (1202 aa)
L486_07737DNA-directed RNA polymerase II subunit RPB4. (163 aa)
L486_08085Anti_prolifrtn domain-containing protein. (556 aa)
L486_08052CMGC/CK2 protein kinase; Belongs to the protein kinase superfamily. (353 aa)
L486_08004HAL protein kinase. (760 aa)
L486_08210G protein beta subunit-like protein. (339 aa)
L486_08358DNA-directed RNA polymerase II subunit RPB11. (161 aa)
L486_00519Quinone oxidoreductase. (319 aa)
L486_00472PKS_ER domain-containing protein. (342 aa)
L486_00343Uncharacterized protein. (411 aa)
L486_00242Uncharacterized protein. (1251 aa)
L486_00155Transcription elongation factor B, polypeptide 1; Belongs to the SKP1 family. (104 aa)
L486_00156Uncharacterized protein. (248 aa)
L486_00090Chromo domain-containing protein. (744 aa)
L486_00062Alcohol dehydrogenase. (336 aa)
L486_02979Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2354 aa)
L486_02975CCR4-NOT transcription complex subunit 3. (665 aa)
L486_02915FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (584 aa)
L486_027161-phosphatidylinositol-4-phosphate 5-kinase. (1017 aa)
L486_02577PLK/PLK1 protein kinase. (773 aa)
L486_02623Polyubiquitin. (381 aa)
L486_02513Cytochrome c oxidase subunit 4. (161 aa)
L486_02484CAMK protein kinase. (733 aa)
L486_02493Phosphatidylinositol 3-kinase; Belongs to the PI3/PI4-kinase family. (1426 aa)
L486_02476Uncharacterized protein. (275 aa)
L486_02455DNA damage checkpoint protein rad24; Belongs to the 14-3-3 family. (258 aa)
L486_02422BUD32 protein kinase. (305 aa)
L486_02401Uncharacterized protein. (938 aa)
L486_02378PRELI/MSF1 domain-containing protein. (302 aa)
L486_02281Uncharacterized protein. (728 aa)
L486_02119Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (213 aa)
L486_02184Chromatin modification-related protein. (485 aa)
L486_02143Uncharacterized protein. (646 aa)
L486_02038Uncharacterized protein. (110 aa)
L486_01970Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (340 aa)
L486_01917Uncharacterized protein. (127 aa)
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (844 aa)
L486_01588STE/STE7/MKK protein kinase. (648 aa)
L486_01702Uncharacterized protein. (750 aa)
L486_01605Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (479 aa)
L486_01597Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (256 aa)
L486_01510DNA-directed RNA polymerase I, II, and III subunit RPABC2. (153 aa)
L486_01475CAMK/CAMKL/CHK1 protein kinase; Belongs to the protein kinase superfamily. (453 aa)
L486_01308Mitochondrial protein. (180 aa)
L486_01253General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (440 aa)
L486_01280Cyclin H; Belongs to the cyclin family. (439 aa)
L486_01200Adenylate cyclase. (2382 aa)
L486_01129Uncharacterized protein. (374 aa)
L486_00926DNA-directed RNA polymerase I, II, and III subunit RPABC3. (163 aa)
L486_00821Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (115 aa)
L486_00668zf-GRF domain-containing protein. (265 aa)
L486_00770CMGC/CDK/CRK7 protein kinase. (1270 aa)
L486_00628zf-4CXXC_R1 domain-containing protein. (918 aa)
L486_00733RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (893 aa)
L486_00662Cytochrome c oxidase subunit 5b. (156 aa)
L486_00444Alcohol dehydrogenase. (358 aa)
L486_00537Transcription initiation factor TFIIH subunit 1. (658 aa)
L486_00552DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (123 aa)
L486_00524CCR4-NOT transcription complex subunit 7/8. (286 aa)
Your Current Organism:
Kwoniella mangroviensis
NCBI taxonomy Id: 1331196
Other names: K. mangroviensis CBS 10435, Kwoniella mangroviensis CBS 10435, Kwoniella mangroviensis CBS10435
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