47 items (Kwoniella mangroviensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	SLX1	Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (435 aa)
	L486_00396	Rad51 domain-containing protein. (411 aa)
	L486_00056	Uncharacterized protein. (278 aa)
	L486_02778	Uncharacterized protein. (250 aa)
	L486_02765	Serine/threonine-protein phosphatase. (308 aa)
	L486_02623	Polyubiquitin. (381 aa)
	L486_02435	RECA_2 domain-containing protein. (590 aa)
	L486_02231	ERCC4 domain-containing protein. (598 aa)
	L486_02045	CIA30 domain-containing protein. (271 aa)
	L486_03820	RAN protein kinase; Belongs to the protein kinase superfamily. (441 aa)
	L486_03387	Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (320 aa)
	L486_03292	Uncharacterized protein. (610 aa)
	L486_03328	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (973 aa)
	L486_07128	Rad51 domain-containing protein. (369 aa)
	L486_06538	ERCC4 domain-containing protein. (836 aa)
	L486_07077	Uncharacterized protein. (1173 aa)
	L486_07393	Uncharacterized protein. (900 aa)
	L486_07272	Uncharacterized protein. (549 aa)
	L486_07365	Uncharacterized protein. (879 aa)
	L486_07382	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (956 aa)
	L486_07606	Uncharacterized protein. (1010 aa)
	L486_03136	Uncharacterized protein. (260 aa)
	L486_03073	FHA domain-containing protein. (791 aa)
	L486_04440	HAL protein kinase. (1025 aa)
	L486_04305	Uncharacterized protein. (185 aa)
	L486_05155	Uncharacterized protein. (564 aa)
	L486_05156	Uncharacterized protein. (146 aa)
	L486_04987	DUF1767 domain-containing protein. (565 aa)
	L486_04674	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2240 aa)
	L486_04672	Serine/threonine-protein phosphatase. (310 aa)
	L486_06304	Topoisomerase 1-associated factor 1. (1172 aa)
	L486_06674	3'-5' exonuclease domain-containing protein. (354 aa)
	L486_06600	Uncharacterized protein. (574 aa)
	L486_06675	3'-5' exonuclease domain-containing protein. (643 aa)
	L486_07078	Uncharacterized protein. (76 aa)
	L486_01441	Asparagine-tRNA ligase. (606 aa)
	L486_01475	CAMK/CAMKL/CHK1 protein kinase; Belongs to the protein kinase superfamily. (453 aa)
	L486_01875	Uncharacterized protein. (996 aa)
	L486_08027	RAN protein kinase. (509 aa)
	L486_08004	HAL protein kinase. (760 aa)
	L486_07803	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (344 aa)
	L486_07664	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (613 aa)
	L486_07591	Polyubiquitin. (160 aa)
	L486_07209	Histone H2B; Belongs to the histone H2B family. (139 aa)
	L486_00878	Uncharacterized protein. (1017 aa)
	L486_00668	zf-GRF domain-containing protein. (265 aa)
	L486_00628	zf-4CXXC_R1 domain-containing protein. (918 aa)

Your Current Organism:

Kwoniella mangroviensis

NCBI taxonomy Id: 1331196
Other names: K. mangroviensis CBS 10435, Kwoniella mangroviensis CBS 10435, Kwoniella mangroviensis CBS10435

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L486_00056	L486_02765	A0A1B9IY15	A0A1B9IX42	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.869
L486_00056	L486_04672	A0A1B9IY15	A0A1B9INQ6	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.869
L486_00396	L486_00628	A0A1B9IYZ8	A0A1B9IZY7	Rad51 domain-containing protein.	zf-4CXXC_R1 domain-containing protein.	0.495
L486_00396	L486_00668	A0A1B9IYZ8	A0A1B9J028	Rad51 domain-containing protein.	zf-GRF domain-containing protein.	0.782
L486_00396	L486_01441	A0A1B9IYZ8	A0A1B9J1W8	Rad51 domain-containing protein.	Asparagine-tRNA ligase.	0.632
L486_00396	L486_01475	A0A1B9IYZ8	A0A1B9J1Z5	Rad51 domain-containing protein.	CAMK/CAMKL/CHK1 protein kinase; Belongs to the protein kinase superfamily.	0.761
L486_00396	L486_01875	A0A1B9IYZ8	A0A1B9J347	Rad51 domain-containing protein.	Uncharacterized protein.	0.968
L486_00396	L486_02045	A0A1B9IYZ8	A0A1B9IV12	Rad51 domain-containing protein.	CIA30 domain-containing protein.	0.632
L486_00396	L486_02435	A0A1B9IYZ8	A0A1B9IW68	Rad51 domain-containing protein.	RECA_2 domain-containing protein.	0.991
L486_00396	L486_02623	A0A1B9IYZ8	A0A1B9IWN4	Rad51 domain-containing protein.	Polyubiquitin.	0.659
L486_00396	L486_02778	A0A1B9IYZ8	A0A1B9IX62	Rad51 domain-containing protein.	Uncharacterized protein.	0.632
L486_00396	L486_03136	A0A1B9IYZ8	A0A1B9ISZ8	Rad51 domain-containing protein.	Uncharacterized protein.	0.632
L486_00396	L486_03292	A0A1B9IYZ8	A0A1B9ITC8	Rad51 domain-containing protein.	Uncharacterized protein.	0.627
L486_00396	L486_03328	A0A1B9IYZ8	A0A1B9ITH4	Rad51 domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.835
L486_00396	L486_03820	A0A1B9IYZ8	A0A1B9IUW7	Rad51 domain-containing protein.	RAN protein kinase; Belongs to the protein kinase superfamily.	0.528
L486_00396	L486_04440	A0A1B9IYZ8	A0A1B9ISA3	Rad51 domain-containing protein.	HAL protein kinase.	0.701
L486_00396	L486_04674	A0A1B9IYZ8	A0A1B9INS0	Rad51 domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.783
L486_00396	L486_04987	A0A1B9IYZ8	A0A1B9IPP8	Rad51 domain-containing protein.	DUF1767 domain-containing protein.	0.806
L486_00396	L486_06538	A0A1B9IYZ8	A0A1B9IJG4	Rad51 domain-containing protein.	ERCC4 domain-containing protein.	0.852
L486_00396	L486_06674	A0A1B9IYZ8	A0A1B9IK96	Rad51 domain-containing protein.	3'-5' exonuclease domain-containing protein.	0.627