STRINGSTRING
MDM34 MDM34 L486_08004 L486_08004 L486_08052 L486_08052 L486_07664 L486_07664 L486_07591 L486_07591 L486_07382 L486_07382 L486_06922 L486_06922 L486_07393 L486_07393 L486_07077 L486_07077 L486_07078 L486_07078 L486_06675 L486_06675 L486_06547 L486_06547 L486_06674 L486_06674 L486_04674 L486_04674 L486_04987 L486_04987 L486_05284 L486_05284 L486_04215 L486_04215 L486_04440 L486_04440 L486_03292 L486_03292 L486_03328 L486_03328 L486_02045 L486_02045 L486_02401 L486_02401 L486_02422 L486_02422 L486_02484 L486_02484 L486_02623 L486_02623 L486_02915 L486_02915 L486_00343 L486_00343 L486_00628 L486_00628 L486_00668 L486_00668 L486_01475 L486_01475 L486_01597 L486_01597
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MDM34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (844 aa)
L486_08004HAL protein kinase. (760 aa)
L486_08052CMGC/CK2 protein kinase; Belongs to the protein kinase superfamily. (353 aa)
L486_07664Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (613 aa)
L486_07591Polyubiquitin. (160 aa)
L486_07382ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (956 aa)
L486_06922FACT complex subunit SPT16. (1045 aa)
L486_07393Uncharacterized protein. (900 aa)
L486_07077Uncharacterized protein. (1173 aa)
L486_07078Uncharacterized protein. (76 aa)
L486_066753'-5' exonuclease domain-containing protein. (643 aa)
L486_06547Uncharacterized protein. (556 aa)
L486_066743'-5' exonuclease domain-containing protein. (354 aa)
L486_04674Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2240 aa)
L486_04987DUF1767 domain-containing protein. (565 aa)
L486_05284Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (350 aa)
L486_04215Nucleolar complex protein 2. (738 aa)
L486_04440HAL protein kinase. (1025 aa)
L486_03292Uncharacterized protein. (610 aa)
L486_03328DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (973 aa)
L486_02045CIA30 domain-containing protein. (271 aa)
L486_02401Uncharacterized protein. (938 aa)
L486_02422BUD32 protein kinase. (305 aa)
L486_02484CAMK protein kinase. (733 aa)
L486_02623Polyubiquitin. (381 aa)
L486_02915FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (584 aa)
L486_00343Uncharacterized protein. (411 aa)
L486_00628zf-4CXXC_R1 domain-containing protein. (918 aa)
L486_00668zf-GRF domain-containing protein. (265 aa)
L486_01475CAMK/CAMKL/CHK1 protein kinase; Belongs to the protein kinase superfamily. (453 aa)
L486_01597Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (256 aa)
Your Current Organism:
Kwoniella mangroviensis
NCBI taxonomy Id: 1331196
Other names: K. mangroviensis CBS 10435, Kwoniella mangroviensis CBS 10435, Kwoniella mangroviensis CBS10435
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