STRINGSTRING
L486_06214 L486_06214 L486_08325 L486_08325 L486_07591 L486_07591 L486_06610 L486_06610 L486_06149 L486_06149 MCM7 MCM7 L486_06697 L486_06697 L486_06210 L486_06210 L486_05954 L486_05954 L486_04728 L486_04728 L486_04625 L486_04625 L486_04856 L486_04856 L486_05238 L486_05238 L486_04081 L486_04081 L486_04120 L486_04120 L486_03205 L486_03205 L486_03334 L486_03334 L486_02045 L486_02045 L486_02083 L486_02083 L486_02082 L486_02082 L486_02623 L486_02623 L486_00342 L486_00342 L486_01642 L486_01642
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
L486_06214DNA helicase; Belongs to the MCM family. (998 aa)
L486_08325Zf-rbx1 domain-containing protein. (91 aa)
L486_07591Polyubiquitin. (160 aa)
L486_06610DNA helicase; Belongs to the MCM family. (965 aa)
L486_06149Uncharacterized protein. (270 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (797 aa)
L486_06697DNA helicase; Belongs to the MCM family. (755 aa)
L486_06210Cyclin; Belongs to the cyclin family. (463 aa)
L486_05954Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (211 aa)
L486_04728Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (829 aa)
L486_04625DNA helicase; Belongs to the MCM family. (874 aa)
L486_04856Cyclin; Belongs to the cyclin family. (489 aa)
L486_05238DNA helicase; Belongs to the MCM family. (929 aa)
L486_04081ANAPC5 domain-containing protein. (729 aa)
L486_04120CMGC/CDK/CDC2 protein kinase; Belongs to the protein kinase superfamily. (296 aa)
L486_03205AAA domain-containing protein. (884 aa)
L486_03334G2/mitotic-specific cyclin 1/2; Belongs to the cyclin family. (537 aa)
L486_02045CIA30 domain-containing protein. (271 aa)
L486_02083Uncharacterized protein. (162 aa)
L486_02082CMGC/CDK/CDK5 protein kinase; Belongs to the protein kinase superfamily. (285 aa)
L486_02623Polyubiquitin. (381 aa)
L486_00342ORC_WH_C domain-containing protein. (443 aa)
L486_01642PA28_beta domain-containing protein. (275 aa)
Your Current Organism:
Kwoniella mangroviensis
NCBI taxonomy Id: 1331196
Other names: K. mangroviensis CBS 10435, Kwoniella mangroviensis CBS 10435, Kwoniella mangroviensis CBS10435
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