STRINGSTRING
L486_08312 L486_08312 L486_08299 L486_08299 L486_07664 L486_07664 L486_06818 L486_06818 L486_07273 L486_07273 L486_06799 L486_06799 L486_06199 L486_06199 L486_06364 L486_06364 L486_05339 L486_05339 L486_05738 L486_05738 L486_04757 L486_04757 L486_05312 L486_05312 L486_04125 L486_04125 L486_04305 L486_04305 L486_03176 L486_03176 FEN1 FEN1 L486_03795 L486_03795 L486_02349 L486_02349 L486_00123 L486_00123 L486_00739 L486_00739 L486_01815 L486_01815
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
L486_08312Replication factor A3. (108 aa)
L486_08299Uncharacterized protein. (137 aa)
L486_07664Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (613 aa)
L486_06818DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (725 aa)
L486_07273DNA polymerase delta subunit 2. (506 aa)
L486_06799Chromo domain-containing protein. (765 aa)
L486_06199Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (330 aa)
L486_06364Zds_C domain-containing protein. (1106 aa)
L486_05339Uncharacterized protein. (614 aa)
L486_05738Uncharacterized protein. (492 aa)
L486_04757DNA replication ATP-dependent helicase Dna2. (1348 aa)
L486_05312UDP-galactopyranose mutase. (527 aa)
L486_04125TPR_REGION domain-containing protein. (512 aa)
L486_04305Uncharacterized protein. (185 aa)
L486_03176DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (510 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (439 aa)
L486_03795DNA polymerase. (1496 aa)
L486_02349DNA polymerase. (1058 aa)
L486_00123Uncharacterized protein. (584 aa)
L486_00739Uncharacterized protein. (611 aa)
L486_01815DNA primase; Belongs to the eukaryotic-type primase small subunit family. (432 aa)
Your Current Organism:
Kwoniella mangroviensis
NCBI taxonomy Id: 1331196
Other names: K. mangroviensis CBS 10435, Kwoniella mangroviensis CBS 10435, Kwoniella mangroviensis CBS10435
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