STRINGSTRING
L486_08299 L486_08299 L486_06610 L486_06610 L486_06675 L486_06675 L486_07078 L486_07078 L486_06604 L486_06604 L486_07077 L486_07077 L486_07393 L486_07393 L486_07382 L486_07382 L486_07209 L486_07209 L486_07591 L486_07591 L486_07684 L486_07684 L486_07664 L486_07664 L486_07886 L486_07886 L486_07882 L486_07882 L486_08004 L486_08004 L486_08312 L486_08312 L486_08503 L486_08503 L486_08027 L486_08027 L486_01882 L486_01882 L486_01642 L486_01642 L486_01475 L486_01475 L486_01462 L486_01462 L486_01390 L486_01390 L486_01222 L486_01222 L486_01146 L486_01146 L486_00979 L486_00979 L486_00668 L486_00668 L486_00628 L486_00628 L486_00342 L486_00342 L486_00296 L486_00296 L486_00244 L486_00244 L486_00123 L486_00123 L486_02855 L486_02855 L486_02623 L486_02623 L486_02551 L486_02551 L486_02544 L486_02544 L486_02484 L486_02484 L486_02455 L486_02455 L486_02193 L486_02193 L486_02082 L486_02082 L486_02083 L486_02083 L486_02077 L486_02077 L486_02045 L486_02045 L486_03820 L486_03820 L486_03790 L486_03790 L486_03618 L486_03618 L486_03516 L486_03516 L486_03328 L486_03328 L486_03292 L486_03292 L486_03205 L486_03205 L486_03127 L486_03127 L486_03073 L486_03073 L486_04440 L486_04440 L486_04120 L486_04120 L486_04125 L486_04125 L486_03980 L486_03980 L486_04081 L486_04081 L486_03950 L486_03950 L486_05312 L486_05312 L486_05238 L486_05238 L486_05155 L486_05155 L486_05172 L486_05172 L486_05156 L486_05156 L486_04989 L486_04989 L486_04987 L486_04987 L486_04726 L486_04726 L486_04891 L486_04891 L486_04625 L486_04625 L486_05959 L486_05959 L486_04728 L486_04728 L486_04674 L486_04674 L486_05954 L486_05954 L486_05889 L486_05889 L486_05882 L486_05882 L486_05809 L486_05809 L486_06364 L486_06364 L486_05396 L486_05396 L486_06214 L486_06214 L486_06697 L486_06697 MCM7 MCM7 L486_06799 L486_06799 L486_06710 L486_06710 L486_06583 L486_06583 L486_06704 L486_06704 L486_06674 L486_06674 L486_06485 L486_06485
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
L486_08299Uncharacterized protein. (137 aa)
L486_06610DNA helicase; Belongs to the MCM family. (965 aa)
L486_066753'-5' exonuclease domain-containing protein. (643 aa)
L486_07078Uncharacterized protein. (76 aa)
L486_06604Uncharacterized protein. (768 aa)
L486_07077Uncharacterized protein. (1173 aa)
L486_07393Uncharacterized protein. (900 aa)
L486_07382ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (956 aa)
L486_07209Histone H2B; Belongs to the histone H2B family. (139 aa)
L486_07591Polyubiquitin. (160 aa)
L486_07684Nuclear pore complex protein Nup160. (1468 aa)
L486_07664Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (613 aa)
L486_07886Kinetochore protein Nuf2. (452 aa)
L486_07882CDC7 protein kinase. (915 aa)
L486_08004HAL protein kinase. (760 aa)
L486_08312Replication factor A3. (108 aa)
L486_08503CAMK protein kinase. (642 aa)
L486_08027RAN protein kinase. (509 aa)
L486_01882Cell cycle arrest protein BUB3. (336 aa)
L486_01642PA28_beta domain-containing protein. (275 aa)
L486_01475CAMK/CAMKL/CHK1 protein kinase; Belongs to the protein kinase superfamily. (453 aa)
L486_01462Cell division control protein 45. (727 aa)
L486_01390Uncharacterized protein. (676 aa)
L486_01222Uncharacterized protein. (762 aa)
L486_01146BUB protein kinase. (1339 aa)
L486_00979NUDE_C domain-containing protein. (779 aa)
L486_00668zf-GRF domain-containing protein. (265 aa)
L486_00628zf-4CXXC_R1 domain-containing protein. (918 aa)
L486_00342ORC_WH_C domain-containing protein. (443 aa)
L486_00296Uncharacterized protein. (542 aa)
L486_00244Kinesin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1045 aa)
L486_00123Uncharacterized protein. (584 aa)
L486_02855Uncharacterized protein. (554 aa)
L486_02623Polyubiquitin. (381 aa)
L486_02551Checkpoint protein; Belongs to the HUS1 family. (307 aa)
L486_02544Uncharacterized protein. (1003 aa)
L486_02484CAMK protein kinase. (733 aa)
L486_02455DNA damage checkpoint protein rad24; Belongs to the 14-3-3 family. (258 aa)
L486_02193Uncharacterized protein. (545 aa)
L486_02082CMGC/CDK/CDK5 protein kinase; Belongs to the protein kinase superfamily. (285 aa)
L486_02083Uncharacterized protein. (162 aa)
L486_02077CENP-C_C domain-containing protein. (724 aa)
L486_02045CIA30 domain-containing protein. (271 aa)
L486_03820RAN protein kinase; Belongs to the protein kinase superfamily. (441 aa)
L486_03790Zf-primase domain-containing protein. (738 aa)
L486_03618Uncharacterized protein. (526 aa)
L486_03516Metallophos domain-containing protein. (562 aa)
L486_03328DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (973 aa)
L486_03292Uncharacterized protein. (610 aa)
L486_03205AAA domain-containing protein. (884 aa)
L486_03127Uncharacterized protein. (715 aa)
L486_03073FHA domain-containing protein. (791 aa)
L486_04440HAL protein kinase. (1025 aa)
L486_04120CMGC/CDK/CDC2 protein kinase; Belongs to the protein kinase superfamily. (296 aa)
L486_04125TPR_REGION domain-containing protein. (512 aa)
L486_03980Mitotic spindle assembly checkpoint protein MAD2. (212 aa)
L486_04081ANAPC5 domain-containing protein. (729 aa)
L486_03950Tyrosine phosphatase. (770 aa)
L486_05312UDP-galactopyranose mutase. (527 aa)
L486_05238DNA helicase; Belongs to the MCM family. (929 aa)
L486_05155Uncharacterized protein. (564 aa)
L486_05172Microtubule Associated protein. (2209 aa)
L486_05156Uncharacterized protein. (146 aa)
L486_04989Replication factor C subunit 2/4. (350 aa)
L486_04987DUF1767 domain-containing protein. (565 aa)
L486_04726Kinetochore protein Spc25. (313 aa)
L486_04891CLASP_N domain-containing protein. (1215 aa)
L486_04625DNA helicase; Belongs to the MCM family. (874 aa)
L486_05959Replication factor A2. (279 aa)
L486_04728Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (829 aa)
L486_04674Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2240 aa)
L486_05954Ubiquitin-conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (211 aa)
L486_05889Uncharacterized protein. (1073 aa)
L486_05882Regulatory subunit for Cdc7 protein kinase. (694 aa)
L486_05809Replication factor C subunit 3/5. (372 aa)
L486_06364Zds_C domain-containing protein. (1106 aa)
L486_05396Replication factor C subunit 2/4. (365 aa)
L486_06214DNA helicase; Belongs to the MCM family. (998 aa)
L486_06697DNA helicase; Belongs to the MCM family. (755 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (797 aa)
L486_06799Chromo domain-containing protein. (765 aa)
L486_06710Uncharacterized protein. (341 aa)
L486_06583Replication factor C subunit 3/5. (356 aa)
L486_06704RP/EB family microtubule-associated protein. (253 aa)
L486_066743'-5' exonuclease domain-containing protein. (354 aa)
L486_06485ELYS domain-containing protein. (806 aa)
Your Current Organism:
Kwoniella mangroviensis
NCBI taxonomy Id: 1331196
Other names: K. mangroviensis CBS 10435, Kwoniella mangroviensis CBS 10435, Kwoniella mangroviensis CBS10435
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