28 items (Kwoniella mangroviensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	L486_04781	Ubiquitin-conjugating enzyme E2 13; Belongs to the ubiquitin-conjugating enzyme family. (134 aa)
	L486_02045	CIA30 domain-containing protein. (271 aa)
	L486_06361	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (3049 aa)
	L486_02631	TPR_REGION domain-containing protein. (678 aa)
	L486_02855	Uncharacterized protein. (554 aa)
	L486_04754	Uncharacterized protein. (1027 aa)
	L486_01597	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (256 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (844 aa)
	L486_01757	ULK/ULK protein kinase. (970 aa)
	L486_05201	Uncharacterized protein. (212 aa)
	L486_02891	EF-hand calcium-binding protein. (162 aa)
	L486_00128	Uncharacterized protein. (52 aa)
	L486_00256	USP domain-containing protein; Belongs to the peptidase C19 family. (625 aa)
	L486_00731	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (126 aa)
	L486_06591	Mitochondrial import receptor subunit TOM40. (380 aa)
	L486_06653	Uncharacterized protein. (219 aa)
	L486_06179	Mitochondrial outer membrane 72K protein. (642 aa)
	L486_06227	Autophagy-related protein. (128 aa)
	L486_06328	Ubiquitin-conjugating enzyme E2. (151 aa)
	L486_07982	Mitofusin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (881 aa)
	L486_07591	Polyubiquitin. (160 aa)
	L486_06547	Uncharacterized protein. (556 aa)
	L486_01170	TPR_REGION domain-containing protein. (785 aa)
	L486_02623	Polyubiquitin. (381 aa)
	L486_08052	CMGC/CK2 protein kinase; Belongs to the protein kinase superfamily. (353 aa)
	L486_05284	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (350 aa)
	L486_03074	Mitochondrial import receptor subunit tom22. (152 aa)
	L486_03372	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (345 aa)

Your Current Organism:

Kwoniella mangroviensis

NCBI taxonomy Id: 1331196
Other names: K. mangroviensis CBS 10435, Kwoniella mangroviensis CBS 10435, Kwoniella mangroviensis CBS10435

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L486_00128	L486_03074	A0A1B9IY81	A0A1B9IST3	Uncharacterized protein.	Mitochondrial import receptor subunit tom22.	0.998
L486_00128	L486_05201	A0A1B9IY81	A0A1B9IQ94	Uncharacterized protein.	Uncharacterized protein.	0.973
L486_00128	L486_06179	A0A1B9IY81	A0A1B9IKP3	Uncharacterized protein.	Mitochondrial outer membrane 72K protein.	0.894
L486_00128	L486_06591	A0A1B9IY81	A0A1B9IK16	Uncharacterized protein.	Mitochondrial import receptor subunit TOM40.	0.986
L486_00128	MDM34	A0A1B9IY81	A0A1B9J300	Uncharacterized protein.	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.	0.518
L486_00256	L486_01170	A0A1B9IYL0	A0A1B9J180	USP domain-containing protein; Belongs to the peptidase C19 family.	TPR_REGION domain-containing protein.	0.651
L486_00256	L486_02045	A0A1B9IYL0	A0A1B9IV12	USP domain-containing protein; Belongs to the peptidase C19 family.	CIA30 domain-containing protein.	0.937
L486_00256	L486_02623	A0A1B9IYL0	A0A1B9IWN4	USP domain-containing protein; Belongs to the peptidase C19 family.	Polyubiquitin.	0.959
L486_00256	L486_02631	A0A1B9IYL0	A0A1B9IWR2	USP domain-containing protein; Belongs to the peptidase C19 family.	TPR_REGION domain-containing protein.	0.651
L486_00256	L486_05201	A0A1B9IYL0	A0A1B9IQ94	USP domain-containing protein; Belongs to the peptidase C19 family.	Uncharacterized protein.	0.835
L486_00256	L486_06179	A0A1B9IYL0	A0A1B9IKP3	USP domain-containing protein; Belongs to the peptidase C19 family.	Mitochondrial outer membrane 72K protein.	0.774
L486_00256	L486_07591	A0A1B9IYL0	A0A1B9IHC7	USP domain-containing protein; Belongs to the peptidase C19 family.	Polyubiquitin.	0.937
L486_00731	L486_01757	A0A1B9IZY4	A0A1B9J2S8	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	ULK/ULK protein kinase.	0.970
L486_00731	L486_03372	A0A1B9IZY4	A0A1B9ITL6	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	0.999
L486_00731	L486_04754	A0A1B9IZY4	A0A1B9INZ5	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Uncharacterized protein.	0.734
L486_00731	L486_06227	A0A1B9IZY4	A0A1B9IKY1	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Autophagy-related protein.	0.955
L486_00731	L486_06653	A0A1B9IZY4	A0A1B9IK74	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Uncharacterized protein.	0.688
L486_00731	L486_07982	A0A1B9IZY4	A0A1B9IG79	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	Mitofusin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.738
L486_01170	L486_00256	A0A1B9J180	A0A1B9IYL0	TPR_REGION domain-containing protein.	USP domain-containing protein; Belongs to the peptidase C19 family.	0.651
L486_01170	L486_02045	A0A1B9J180	A0A1B9IV12	TPR_REGION domain-containing protein.	CIA30 domain-containing protein.	0.670