STRINGSTRING
L486_02344 L486_02344 L486_08496 L486_08496 L486_08532 L486_08532 L486_08531 L486_08531 L486_08193 L486_08193 L486_08171 L486_08171 L486_08143 L486_08143 L486_08158 L486_08158 L486_07971 L486_07971 L486_08099 L486_08099 L486_08109 L486_08109 L486_07808 L486_07808 L486_07483 L486_07483 L486_07815 L486_07815 L486_07511 L486_07511 L486_07835 L486_07835 L486_07809 L486_07809 L486_07271 L486_07271 L486_07295 L486_07295 L486_07238 L486_07238 TRM8 TRM8 L486_07294 L486_07294 L486_07317 L486_07317 L486_07408 L486_07408 L486_07030 L486_07030 L486_07123 L486_07123 L486_07037 L486_07037 L486_07147 L486_07147 L486_06998 L486_06998 L486_06548 L486_06548 L486_07108 L486_07108 L486_06438 L486_06438 L486_06554 L486_06554 L486_06465 L486_06465 L486_06471 L486_06471 L486_06796 L486_06796 L486_06553 L486_06553 L486_06772 L486_06772 L486_06724 L486_06724 L486_06809 L486_06809 L486_06770 L486_06770 L486_06707 L486_06707 L486_06209 L486_06209 L486_06126 L486_06126 L486_06807 L486_06807 L486_06213 L486_06213 L486_06353 L486_06353 L486_06367 L486_06367 L486_05464 L486_05464 L486_05550 L486_05550 L486_05549 L486_05549 L486_05364 L486_05364 L486_05610 L486_05610 L486_05661 L486_05661 L486_05652 L486_05652 L486_05727 L486_05727 L486_05737 L486_05737 L486_05615 L486_05615 L486_04634 L486_04634 L486_05910 L486_05910 L486_04788 L486_04788 L486_04799 L486_04799 L486_04819 L486_04819 L486_04635 L486_04635 L486_04991 L486_04991 L486_04980 L486_04980 L486_05076 L486_05076 L486_05029 L486_05029 L486_05154 L486_05154 L486_05294 L486_05294 L486_05199 L486_05199 L486_04019 L486_04019 L486_03905 L486_03905 L486_04070 L486_04070 L486_04085 L486_04085 L486_04162 L486_04162 L486_04047 L486_04047 L486_04163 L486_04163 L486_04103 L486_04103 L486_04241 L486_04241 L486_04304 L486_04304 L486_04426 L486_04426 L486_04480 L486_04480 L486_04515 L486_04515 L486_04556 L486_04556 L486_04569 L486_04569 L486_04447 L486_04447 L486_04583 L486_04583 L486_03090 L486_03090 L486_04557 L486_04557 L486_03163 L486_03163 L486_03262 L486_03262 L486_03327 L486_03327 L486_03465 L486_03465 L486_03486 L486_03486 L486_03451 L486_03451 L486_03562 L486_03562 L486_03589 L486_03589 L486_03692 L486_03692 L486_03760 L486_03760 L486_03854 L486_03854 L486_03857 L486_03857 L486_03861 L486_03861 L486_02062 L486_02062 L486_03858 L486_03858 L486_02208 L486_02208 L486_02201 L486_02201 L486_02372 L486_02372 L486_02476 L486_02476 L486_02507 L486_02507 L486_02537 L486_02537 L486_02644 L486_02644 L486_02670 L486_02670 L486_02805 L486_02805 L486_02829 L486_02829 L486_02890 L486_02890 L486_02814 L486_02814 L486_02920 L486_02920 L486_02950 L486_02950 L486_02988 L486_02988 L486_00041 L486_00041 L486_00045 L486_00045 L486_00084 L486_00084 L486_00297 L486_00297 L486_00325 L486_00325 L486_00393 L486_00393 L486_00408 L486_00408 L486_00435 L486_00435 L486_00500 L486_00500 L486_00581 L486_00581 L486_00619 L486_00619 L486_00660 L486_00660 L486_00724 L486_00724 L486_00720 L486_00720 L486_00775 L486_00775 L486_00851 L486_00851 L486_00891 L486_00891 L486_00955 L486_00955 L486_00983 L486_00983 L486_00870 L486_00870 L486_01016 L486_01016 L486_01032 L486_01032 L486_01211 L486_01211 L486_01495 L486_01495 L486_01549 L486_01549 L486_01602 L486_01602 L486_01496 L486_01496 L486_01655 L486_01655 L486_01685 L486_01685 L486_01735 L486_01735 L486_01670 L486_01670 L486_01782 L486_01782 L486_01870 L486_01870 L486_01915 L486_01915 L486_01946 L486_01946
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
L486_023442,3-bisphosphoglycerate-independent phosphoglycerate mutase. (534 aa)
L486_08496Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (379 aa)
L486_08532Uncharacterized protein. (309 aa)
L486_08531Zn(2)-C6 fungal-type domain-containing protein. (183 aa)
L486_08193Uncharacterized protein. (584 aa)
L486_08171Zn(2)-C6 fungal-type domain-containing protein. (1038 aa)
L486_081436-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (522 aa)
L486_08158S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (286 aa)
L486_07971Glyceraldehyde-3-phosphate dehydrogenase. (339 aa)
L486_08099SGL domain-containing protein. (340 aa)
L486_08109Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (749 aa)
L486_07808Dihydroxyacetone kinase. (600 aa)
L486_074836-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (286 aa)
L486_07815Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (292 aa)
L486_07511Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (790 aa)
L486_07835Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa)
L486_07809Ribose 5-phosphate isomerase. (199 aa)
L486_07271Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (172 aa)
L486_07295Catalase domain-containing protein. (332 aa)
L486_07238Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (362 aa)
TRM8tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (296 aa)
L486_07294Uncharacterized protein. (298 aa)
L486_073172-oxoglutarate dehydrogenase E2 component (Dihydrolipoamide succinyltransferase). (476 aa)
L486_07408Oxoglutarate dehydrogenase (Succinyl-transferring), E1 component. (1020 aa)
L486_07030Thioredoxin reductase GliT. (351 aa)
L486_07123Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (416 aa)
L486_07037Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (373 aa)
L486_07147Cytoplasmic protein. (467 aa)
L486_06998Uncharacterized protein. (82 aa)
L486_06548Glucose-6-phosphate isomerase; Belongs to the GPI family. (557 aa)
L486_07108Dihydroxyacetone kinase. (591 aa)
L486_06438Isocitrate lyase. (491 aa)
L486_06554Uncharacterized protein. (733 aa)
L486_06465SET domain-containing protein. (531 aa)
L486_06471Phosphotransferase. (485 aa)
L486_06796S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (383 aa)
L486_06553Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (422 aa)
L486_06772SET domain-containing protein. (534 aa)
L486_06724Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (557 aa)
L486_06809GFA domain-containing protein. (75 aa)
L486_06770Multifunctional beta-oxidation protein. (906 aa)
L486_06707Transaldolase. (380 aa)
L486_06209Aspartate aminotransferase. (429 aa)
L486_06126Pyruvate kinase; Belongs to the pyruvate kinase family. (584 aa)
L486_06807Uncharacterized protein; Belongs to the GMC oxidoreductase family. (559 aa)
L486_06213Aspartate aminotransferase. (417 aa)
L486_06353Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1221 aa)
L486_06367TPR_REGION domain-containing protein. (388 aa)
L486_05464Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (426 aa)
L486_05550Phytanoyl-CoA dioxygenase. (319 aa)
L486_05549Uncharacterized protein. (593 aa)
L486_05364Phosphoserine transaminase. (421 aa)
L486_05610Uncharacterized protein. (122 aa)
L486_05661Malic enzyme. (557 aa)
L486_05652Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (159 aa)
L486_05727SGL domain-containing protein. (269 aa)
L486_05737Phosphopyruvate hydratase. (466 aa)
L486_05615Uncharacterized protein. (559 aa)
L486_04634Mac domain-containing protein. (210 aa)
L486_05910Probable acetate kinase. (434 aa)
L486_047886-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (308 aa)
L486_04799Uncharacterized protein. (733 aa)
L486_04819Triosephosphate isomerase. (252 aa)
L486_04635Transketolase. (647 aa)
L486_04991Ribose-phosphate pyrophosphokinase. (324 aa)
L486_04980Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (498 aa)
L486_05076Pyruvate dehydrogenase X component. (348 aa)
L486_05029Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (417 aa)
L486_05154Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (309 aa)
L486_05294Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (698 aa)
L486_05199Alanine transaminase. (525 aa)
L486_04019Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1048 aa)
L486_03905Uncharacterized protein. (183 aa)
L486_04070Cysteine synthase A. (470 aa)
L486_04085Fumarate hydratase, mitochondrial. (502 aa)
L486_04162MFS domain-containing protein. (505 aa)
L486_04047MFS domain-containing protein. (560 aa)
L486_04163Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (712 aa)
L486_04103Cleft lip and palate associated transmembrane protein. (616 aa)
L486_04241Phosphotransferase. (577 aa)
L486_04304MFS domain-containing protein. (534 aa)
L486_04426Uncharacterized protein. (384 aa)
L486_04480Dityrosine transporter. (665 aa)
L486_04515Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (640 aa)
L486_04556Acetyl-coenzyme A synthetase. (669 aa)
L486_04569BZIP domain-containing protein. (309 aa)
L486_04447Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (421 aa)
L486_04583D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (505 aa)
L486_03090Isocitrate dehydrogenase, NAD-dependent. (380 aa)
L486_04557Uncharacterized protein. (356 aa)
L486_03163Gluconolactonase. (486 aa)
L486_03262ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (967 aa)
L486_03327Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (506 aa)
L486_03465Uncharacterized protein. (432 aa)
L486_03486Gluconokinase. (240 aa)
L486_03451Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (688 aa)
L486_03562Dihydrolipoyl dehydrogenase. (510 aa)
L486_03589Pre-rRNA-processing protein TSR1. (826 aa)
L486_03692Ribose-5-phosphate isomerase. (320 aa)
L486_03760Uncharacterized protein. (242 aa)
L486_03854Tartrate dehydrogenase. (379 aa)
L486_03857Uncharacterized protein. (315 aa)
L486_03861Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (413 aa)
L486_02062Ribose-phosphate pyrophosphokinase. (328 aa)
L486_03858Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (379 aa)
L486_022086-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa)
L486_02201Threonine dehydratase. (603 aa)
L486_02372Gluconolactonase. (406 aa)
L486_02476Uncharacterized protein. (275 aa)
L486_02507Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (323 aa)
L486_02537Isocitrate lyase. (551 aa)
L486_02644Uncharacterized protein. (151 aa)
L486_02670Nipsnap family protein. (311 aa)
L486_02805Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (378 aa)
L486_02829Uncharacterized protein. (164 aa)
L486_02890Malate synthase; Belongs to the malate synthase family. (543 aa)
L486_02814Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (166 aa)
L486_02920GFA domain-containing protein. (140 aa)
L486_0295025S rRNA adenine-N(1) methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA; Belongs to the BMT2 family. (321 aa)
L486_02988Malic enzyme. (610 aa)
L486_00041Citrate synthase; Belongs to the citrate synthase family. (464 aa)
L486_00045Fructose-1,6-bisphosphatase I; Belongs to the FBPase class 1 family. (349 aa)
L486_00084Uncharacterized protein. (306 aa)
L486_002973-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (531 aa)
L486_00325SGL domain-containing protein. (320 aa)
L486_00393WAPL domain-containing protein. (956 aa)
L486_00408Succinate dehydrogenase, cytochrome b556 subunit. (202 aa)
L486_00435Regucalcin. (317 aa)
L486_00500Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (284 aa)
L486_00581Alanine-glyoxylate transaminase/serine-glyoxylate transaminase/serine-pyruvate transaminase. (411 aa)
L486_00619Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (639 aa)
L486_00660MFS domain-containing protein. (638 aa)
L486_00724L-serine ammonia-lyase. (353 aa)
L486_00720MACPF domain-containing protein. (979 aa)
L486_00775L-serine ammonia-lyase. (336 aa)
L486_00851Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (637 aa)
L486_00891Phosphoenolpyruvate carboxykinase (ATP). (550 aa)
L486_00955Malate dehydrogenase (Oxaloacetate-decarboxylating). (625 aa)
L486_00983Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (908 aa)
L486_00870GFA domain-containing protein. (170 aa)
L486_01016Uncharacterized protein. (358 aa)
L486_01032Methylmalonate-semialdehyde dehydrogenase (Acylating). (555 aa)
L486_012113-hydroxybutyryl-CoA dehydrogenase. (310 aa)
L486_01495Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
L486_01549Zn(2)-C6 fungal-type domain-containing protein. (895 aa)
L486_01602Aminotran_1_2 domain-containing protein. (987 aa)
L486_01496Malate dehydrogenase. (339 aa)
L486_01655Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (561 aa)
L486_01685Beta-lactamase domain-containing protein. (420 aa)
L486_01735Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (412 aa)
L486_01670FMN hydroxy acid dehydrogenase domain-containing protein. (418 aa)
L486_01782Cysteine synthase. (372 aa)
L486_01870Malate dehydrogenase, NAD-dependent; Belongs to the LDH/MDH superfamily. (335 aa)
L486_01915PALP domain-containing protein. (397 aa)
L486_01946Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (491 aa)
Your Current Organism:
Kwoniella mangroviensis
NCBI taxonomy Id: 1331196
Other names: K. mangroviensis CBS 10435, Kwoniella mangroviensis CBS 10435, Kwoniella mangroviensis CBS10435
Server load: low (18%) [HD]