47 items (Kwoniella mangroviensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	L486_01832	Uncharacterized protein. (242 aa)
	L486_08312	Replication factor A3. (108 aa)
	L486_08299	Uncharacterized protein. (137 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (717 aa)
	L486_07803	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (344 aa)
	L486_07595	DNA repair and recombination protein RAD54-like protein. (817 aa)
	L486_07664	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (613 aa)
	L486_07382	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (956 aa)
	L486_07273	DNA polymerase delta subunit 2. (506 aa)
	L486_07272	Uncharacterized protein. (549 aa)
	L486_07393	Uncharacterized protein. (900 aa)
	L486_07051	DNA repair and recombination protein RAD54B. (1082 aa)
	L486_07077	Uncharacterized protein. (1173 aa)
	L486_06538	ERCC4 domain-containing protein. (836 aa)
	L486_07128	Rad51 domain-containing protein. (369 aa)
	L486_07078	Uncharacterized protein. (76 aa)
	L486_06799	Chromo domain-containing protein. (765 aa)
	L486_06087	Cytoplasmic protein. (323 aa)
	L486_06361	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (3049 aa)
	L486_05422	Nuclear mRNA splicing protein. (337 aa)
	L486_06364	Zds_C domain-containing protein. (1106 aa)
	L486_05542	Uncharacterized protein. (153 aa)
	L486_05583	Uncharacterized protein. (185 aa)
	L486_05630	26S proteasome complex subunit DSS1. (107 aa)
	L486_05677	DNA repair protein RAD50. (1360 aa)
	L486_05738	Uncharacterized protein. (492 aa)
	L486_05959	Replication factor A2. (279 aa)
	L486_05973	Uncharacterized protein. (159 aa)
	L486_05312	UDP-galactopyranose mutase. (527 aa)
	L486_04125	TPR_REGION domain-containing protein. (512 aa)
	L486_04305	Uncharacterized protein. (185 aa)
	L486_03108	Uncharacterized protein. (1660 aa)
	L486_03328	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (973 aa)
	L486_02231	ERCC4 domain-containing protein. (598 aa)
	L486_02349	DNA polymerase. (1058 aa)
	L486_02431	BRCT domain-containing protein. (902 aa)
	L486_02435	RECA_2 domain-containing protein. (590 aa)
	L486_00123	Uncharacterized protein. (584 aa)
	L486_00396	Rad51 domain-containing protein. (411 aa)
	L486_00668	zf-GRF domain-containing protein. (265 aa)
	L486_00980	SAE2 domain-containing protein. (895 aa)
	L486_01298	ATP-dependent DNA helicase; Belongs to the helicase family. (619 aa)
	L486_01299	ATP-dependent RNA helicase ROK1. (615 aa)
	L486_01355	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa)
	L486_01357	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (703 aa)
	L486_01439	PITH domain-containing protein. (208 aa)
	L486_01875	Uncharacterized protein. (996 aa)

Your Current Organism:

Kwoniella mangroviensis

NCBI taxonomy Id: 1331196
Other names: K. mangroviensis CBS 10435, Kwoniella mangroviensis CBS 10435, Kwoniella mangroviensis CBS10435

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L486_00123	L486_05959	A0A1B9IY90	A0A1B9INZ1	Uncharacterized protein.	Replication factor A2.	0.797
L486_00123	L486_06538	A0A1B9IY90	A0A1B9IJG4	Uncharacterized protein.	ERCC4 domain-containing protein.	0.671
L486_00123	L486_07664	A0A1B9IY90	A0A1B9IH48	Uncharacterized protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.785
L486_00396	L486_00668	A0A1B9IYZ8	A0A1B9J028	Rad51 domain-containing protein.	zf-GRF domain-containing protein.	0.782
L486_00396	L486_01357	A0A1B9IYZ8	A0A1B9J1S6	Rad51 domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.855
L486_00396	L486_01875	A0A1B9IYZ8	A0A1B9J347	Rad51 domain-containing protein.	Uncharacterized protein.	0.968
L486_00396	L486_02349	A0A1B9IYZ8	A0A1B9IVX3	Rad51 domain-containing protein.	DNA polymerase.	0.771
L486_00396	L486_02431	A0A1B9IYZ8	A0A1B9IW51	Rad51 domain-containing protein.	BRCT domain-containing protein.	0.790
L486_00396	L486_02435	A0A1B9IYZ8	A0A1B9IW68	Rad51 domain-containing protein.	RECA_2 domain-containing protein.	0.991
L486_00396	L486_03108	A0A1B9IYZ8	A0A1B9ISV7	Rad51 domain-containing protein.	Uncharacterized protein.	0.584
L486_00396	L486_03328	A0A1B9IYZ8	A0A1B9ITH4	Rad51 domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.835
L486_00396	L486_05677	A0A1B9IYZ8	A0A1B9IMN0	Rad51 domain-containing protein.	DNA repair protein RAD50.	0.830
L486_00396	L486_05738	A0A1B9IYZ8	A0A1B9IMU9	Rad51 domain-containing protein.	Uncharacterized protein.	0.529
L486_00396	L486_05959	A0A1B9IYZ8	A0A1B9INZ1	Rad51 domain-containing protein.	Replication factor A2.	0.757
L486_00396	L486_06361	A0A1B9IYZ8	A0A1B9ILN1	Rad51 domain-containing protein.	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	0.849
L486_00396	L486_06538	A0A1B9IYZ8	A0A1B9IJG4	Rad51 domain-containing protein.	ERCC4 domain-containing protein.	0.852
L486_00396	L486_07051	A0A1B9IYZ8	A0A1B9IJB5	Rad51 domain-containing protein.	DNA repair and recombination protein RAD54B.	0.655
L486_00396	L486_07077	A0A1B9IYZ8	A0A1B9IJE1	Rad51 domain-containing protein.	Uncharacterized protein.	0.840
L486_00396	L486_07078	A0A1B9IYZ8	A0A1B9IJP8	Rad51 domain-containing protein.	Uncharacterized protein.	0.840
L486_00396	L486_07128	A0A1B9IYZ8	A0A1B9IJJ5	Rad51 domain-containing protein.	Rad51 domain-containing protein.	0.951