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fabH fabH acsA acsA ALR22405.1 ALR22405.1 ALR22460.1 ALR22460.1 fabZ fabZ accA accA ALR20549.1 ALR20549.1 ALR20582.1 ALR20582.1 ALR20884.1 ALR20884.1 ALR22580.1 ALR22580.1 ALR20887.1 ALR20887.1 ALR22645.1 ALR22645.1 accD accD ALR21316.1 ALR21316.1 ALR21368.1 ALR21368.1 ackA ackA ALR21499.1 ALR21499.1 ALR21546.1 ALR21546.1 ALR21629.1 ALR21629.1 ALR21909.1 ALR21909.1 ALR22185.1 ALR22185.1 ALR22186.1 ALR22186.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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fabH3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (322 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (648 aa)
ALR22405.12-nitropropane dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
ALR22460.1Betaine aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (492 aa)
fabZbeta-hydroxyacyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (160 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (314 aa)
ALR20549.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
ALR20582.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
ALR20884.1ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
ALR22580.1beta-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
ALR20887.13-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (419 aa)
ALR22645.1Acylphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)
accDacetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (283 aa)
ALR21316.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
ALR21368.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
ALR21499.1Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (491 aa)
ALR21546.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
ALR21629.1enoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
ALR21909.1Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
ALR22185.1acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (159 aa)
ALR22186.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
Your Current Organism:
Sphingobium baderi
NCBI taxonomy Id: 1332080
Other names: CCM 7981, DSM 25433, S. baderi, Sphingobium baderi Kaur et al. 2013, strain LL03
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