STRINGSTRING
gcvPA gcvPA ALR19020.1 ALR19020.1 ALR19021.1 ALR19021.1 ALR19022.1 ALR19022.1 ALR19047.1 ALR19047.1 ALR19091.1 ALR19091.1 ALR19204.1 ALR19204.1 ALR19206.1 ALR19206.1 ALR19296.1 ALR19296.1 ALR19333.1 ALR19333.1 ALR19344.1 ALR19344.1 gpsA gpsA ALR19412.1 ALR19412.1 ALR19463.1 ALR19463.1 pyrD pyrD ALR19725.1 ALR19725.1 ALR19800.1 ALR19800.1 ALR19861.1 ALR19861.1 ALR22429.1 ALR22429.1 ALR19989.1 ALR19989.1 ALR20064.1 ALR20064.1 apt apt ALR20245.1 ALR20245.1 ALR20392.1 ALR20392.1 ALR20404.1 ALR20404.1 ALR20456.1 ALR20456.1 ALR22512.1 ALR22512.1 gcvH gcvH ALR20507.1 ALR20507.1 ALR20709.1 ALR20709.1 ALR20750.1 ALR20750.1 ALR20758.1 ALR20758.1 ALR20759.1 ALR20759.1 ALR20774.1 ALR20774.1 ALR20776.1 ALR20776.1 ALR20784.1 ALR20784.1 ALR21117.1 ALR21117.1 ALR21120.1 ALR21120.1 ALR21283.1 ALR21283.1 ALR22673.1 ALR22673.1 ALR21418.1 ALR21418.1 ALR21599.1 ALR21599.1 ALR21705.1 ALR21705.1 nuoK nuoK nuoI nuoI ALR21711.1 ALR21711.1 ALR21712.1 ALR21712.1 nuoC nuoC nuoB nuoB ALR21731.1 ALR21731.1 ALR22716.1 ALR22716.1 ALR21798.1 ALR21798.1 ALR21805.1 ALR21805.1 ALR21806.1 ALR21806.1 ALR21814.1 ALR21814.1 ALR21815.1 ALR21815.1 ALR21819.1 ALR21819.1 ALR22750.1 ALR22750.1 ALR21849.1 ALR21849.1 ALR21941.1 ALR21941.1 ALR21943.1 ALR21943.1 ALR22049.1 ALR22049.1 ALR22053.1 ALR22053.1 ALR22086.1 ALR22086.1 sucA sucA ALR22245.1 ALR22245.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gcvPAGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (452 aa)
ALR19020.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
ALR19021.1Molybdopterin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
ALR19022.1Xanthine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (732 aa)
ALR19047.1Glycerol-3-phosphate dehydrogenase; In Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (502 aa)
ALR19091.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
ALR19204.13-beta hydroxysteroid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
ALR19206.1Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
ALR19296.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
ALR19333.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
ALR19344.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (323 aa)
ALR19412.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa)
ALR19463.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)
pyrDDihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (345 aa)
ALR19725.1FMN-dependent monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
ALR19800.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
ALR19861.1Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (869 aa)
ALR22429.1Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (628 aa)
ALR19989.1Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (351 aa)
ALR20064.1Cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (430 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (178 aa)
ALR20245.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
ALR20392.14-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
ALR20404.1LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
ALR20456.1Alkyl hydroperoxide reductase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)
ALR22512.1Aminomethyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (123 aa)
ALR20507.1Glycine dehydrogenase; Acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (523 aa)
ALR20709.1D-glycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)
ALR20750.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
ALR20758.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
ALR20759.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
ALR20774.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
ALR20776.1LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
ALR20784.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
ALR21117.1Taurine dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
ALR21120.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
ALR21283.1Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (435 aa)
ALR22673.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
ALR21418.1Carboxymuconolactone decarboxylase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (117 aa)
ALR21599.1Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (462 aa)
ALR21705.1NADH:ubiquinone oxidoreductase subunit L; Derived by automated computational analysis using gene prediction method: Protein Homology. (677 aa)
nuoKNADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (101 aa)
nuoINADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (161 aa)
ALR21711.1NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (438 aa)
ALR21712.1NADH dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
nuoCNADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. (278 aa)
nuoBNADH-quinone oxidoreductase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa)
ALR21731.1Branched-chain alpha-keto acid dehydrogenase subunit E2; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
ALR22716.12-oxoisovalerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
ALR21798.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
ALR21805.1LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
ALR21806.1Bile-acid 7-alpha dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
ALR21814.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
ALR21815.1LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
ALR21819.1Methylene-tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
ALR22750.1(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
ALR21849.1Aromatic-ring-hydroxylating dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
ALR21941.1Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (605 aa)
ALR21943.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
ALR22049.1Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
ALR22053.1Alkane 1-monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (369 aa)
ALR22086.1Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (416 aa)
sucASucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (931 aa)
ALR22245.1NADH dehydrogenase; Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
Your Current Organism:
Sphingobium baderi
NCBI taxonomy Id: 1332080
Other names: CCM 7981, DSM 25433, S. baderi, Sphingobium baderi Kaur et al. 2013, strain LL03
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.