STRINGSTRING
ALR19020.1 ALR19020.1 ALR19021.1 ALR19021.1 ALR19022.1 ALR19022.1 ALR19043.1 ALR19043.1 glpX glpX ALR19068.1 ALR19068.1 ALR19088.1 ALR19088.1 dapA dapA ALR19206.1 ALR19206.1 ALR22299.1 ALR22299.1 ALR19254.1 ALR19254.1 ALR19308.1 ALR19308.1 ALR19344.1 ALR19344.1 ALR22331.1 ALR22331.1 ALR19381.1 ALR19381.1 hemC hemC ALR19395.1 ALR19395.1 gltX gltX prs prs ALR19443.1 ALR19443.1 ALR19450.1 ALR19450.1 ALR22343.1 ALR22343.1 ALR19463.1 ALR19463.1 ALR19518.1 ALR19518.1 ALR19561.1 ALR19561.1 ALR19596.1 ALR19596.1 ALR22367.1 ALR22367.1 acsA acsA ALR19737.1 ALR19737.1 ALR19759.1 ALR19759.1 ALR19760.1 ALR19760.1 dapD dapD ALR19860.1 ALR19860.1 ALR19861.1 ALR19861.1 ALR19862.1 ALR19862.1 ALR19863.1 ALR19863.1 ppc ppc pckA pckA ALR19905.1 ALR19905.1 ALR22407.1 ALR22407.1 ALR19926.1 ALR19926.1 gabD gabD ALR19976.1 ALR19976.1 ALR19987.1 ALR19987.1 ALR19994.1 ALR19994.1 argD argD cysC cysC ALR20069.1 ALR20069.1 ALR20182.1 ALR20182.1 ALR22460.1 ALR22460.1 ALR20186.1 ALR20186.1 ALR20187.1 ALR20187.1 ALR20200.1 ALR20200.1 ALR20202.1 ALR20202.1 ALR20205.1 ALR20205.1 ALR20206.1 ALR20206.1 ALR20207.1 ALR20207.1 ALR20208.1 ALR20208.1 ALR20210.1 ALR20210.1 folD folD lysA lysA ALR20263.1 ALR20263.1 tal tal ALR20342.1 ALR20342.1 accA accA ALR20392.1 ALR20392.1 tpiA tpiA ALR22498.1 ALR22498.1 thrB thrB ALR22508.1 ALR22508.1 ALR20580.1 ALR20580.1 ALR20616.1 ALR20616.1 ALR20618.1 ALR20618.1 ALR20622.1 ALR20622.1 ALR20676.1 ALR20676.1 ALR20681.1 ALR20681.1 ALR20709.1 ALR20709.1 ALR22546.1 ALR22546.1 gpmA gpmA ALR22555.1 ALR22555.1 ALR22557.1 ALR22557.1 ALR20761.1 ALR20761.1 ALR20767.1 ALR20767.1 ALR20791.1 ALR20791.1 dapA-2 dapA-2 ALR22574.1 ALR22574.1 zwf zwf edd edd ALR20857.1 ALR20857.1 ALR20858.1 ALR20858.1 pgl pgl ALR20863.1 ALR20863.1 ALR20864.1 ALR20864.1 ALR20867.1 ALR20867.1 ALR20889.1 ALR20889.1 ALR20891.1 ALR20891.1 dapB dapB ALR21026.1 ALR21026.1 ALR21028.1 ALR21028.1 ALR22604.1 ALR22604.1 pgi pgi ALR21100.1 ALR21100.1 ALR21101.1 ALR21101.1 ALR21102.1 ALR21102.1 ALR21103.1 ALR21103.1 ALR21105.1 ALR21105.1 ALR21109.1 ALR21109.1 glyA glyA ALR21127.1 ALR21127.1 ALR21139.1 ALR21139.1 glcB glcB ALR21145.1 ALR21145.1 ALR21146.1 ALR21146.1 ALR21147.1 ALR21147.1 ALR21148.1 ALR21148.1 ALR21168.1 ALR21168.1 ALR21172.1 ALR21172.1 asd asd ALR21226.1 ALR21226.1 ALR22645.1 ALR22645.1 accD accD ALR21281.1 ALR21281.1 ALR21283.1 ALR21283.1 ALR21316.1 ALR21316.1 ALR21368.1 ALR21368.1 ackA ackA pckA-2 pckA-2 ALR21409.1 ALR21409.1 ALR22674.1 ALR22674.1 ALR21422.1 ALR21422.1 ALR22677.1 ALR22677.1 ALR21434.1 ALR21434.1 ALR21485.1 ALR21485.1 ALR21495.1 ALR21495.1 ALR21496.1 ALR21496.1 ALR21497.1 ALR21497.1 ALR21499.1 ALR21499.1 ALR21502.1 ALR21502.1 glnA glnA ALR21563.1 ALR21563.1 ALR21584.1 ALR21584.1 ALR21599.1 ALR21599.1 pdhA pdhA eno eno pdxH pdxH sseA sseA fumC fumC ALR21672.1 ALR21672.1 gltX-2 gltX-2 gltA gltA ALR21722.1 ALR21722.1 pgk pgk gapA gapA ALR21724.1 ALR21724.1 ALR21798.1 ALR21798.1 ALR21805.1 ALR21805.1 ALR21819.1 ALR21819.1 ALR21828.1 ALR21828.1 ALR21829.1 ALR21829.1 ALR21839.1 ALR21839.1 ALR21840.1 ALR21840.1 ALR22751.1 ALR22751.1 sucC sucC ALR21907.1 ALR21907.1 cysQ cysQ ALR21914.1 ALR21914.1 ALR21925.1 ALR21925.1 ALR21941.1 ALR21941.1 ALR21942.1 ALR21942.1 ALR21943.1 ALR21943.1 ALR21950.1 ALR21950.1 ALR22766.1 ALR22766.1 ALR21972.1 ALR21972.1 ALR21978.1 ALR21978.1 ALR22013.1 ALR22013.1 ALR22014.1 ALR22014.1 ectC ectC ALR22016.1 ALR22016.1 ectA ectA ALR22052.1 ALR22052.1 ALR22085.1 ALR22085.1 ALR22086.1 ALR22086.1 sucA sucA sucD sucD mdh mdh ALR22092.1 ALR22092.1 dapF dapF ALR22185.1 ALR22185.1 ALR22186.1 ALR22186.1 ALR22188.1 ALR22188.1 dapE dapE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALR19020.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
ALR19021.1Molybdopterin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
ALR19022.1Xanthine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (732 aa)
ALR19043.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
glpXType II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
ALR19068.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
ALR19088.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa)
ALR19206.1Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
ALR22299.1Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1513 aa)
ALR19254.1Nitric oxide reductase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (747 aa)
ALR19308.1Catalyzes the hydrolysis of allophanate; Derived by automated computational analysis using gene prediction method: Protein Homology. (589 aa)
ALR19344.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (123 aa)
ALR22331.1Alkene reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
ALR19381.1Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (220 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (308 aa)
ALR19395.1uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (222 aa)
gltXglutamine--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (444 aa)
prsPhosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (311 aa)
ALR19443.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
ALR19450.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (101 aa)
ALR22343.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
ALR19463.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)
ALR19518.1Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (753 aa)
ALR19561.1Carboxymethylenebutenolidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
ALR19596.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
ALR22367.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (648 aa)
ALR19737.1Nitric oxide reductase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (747 aa)
ALR19759.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa)
ALR19760.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (386 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transferase hexapeptide repeat family. (278 aa)
ALR19860.1uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (261 aa)
ALR19861.1Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. (869 aa)
ALR19862.1Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
ALR19863.1Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (839 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (900 aa)
pckAPhosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (532 aa)
ALR19905.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (421 aa)
ALR22407.1citryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (271 aa)
ALR19926.1Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
gabDNAD-dependent succinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
ALR19976.1Carboxymethylenebutenolidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
ALR19987.1Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (506 aa)
ALR19994.1Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
argDAcetylornithine aminotransferase; Catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (399 aa)
cysCAdenylyltransferase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (637 aa)
ALR20069.1Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
ALR20182.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
ALR22460.1Betaine aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (492 aa)
ALR20186.1Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
ALR20187.1(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)
ALR20200.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
ALR20202.1Geraniol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
ALR20205.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (477 aa)
ALR20206.1Catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
ALR20207.13-oxoadipate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
ALR20208.13-oxoadipate CoA-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
ALR20210.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (297 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa)
ALR20263.1Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
talFructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa)
ALR20342.1Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (406 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (314 aa)
ALR20392.14-carboxymuconolactone decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (246 aa)
ALR22498.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
thrBHomoserine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudomonas-type ThrB family. (325 aa)
ALR22508.1Cysteine synthase; CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
ALR20580.1Gluconolaconase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
ALR20616.1S-(hydroxymethyl)glutathione dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa)
ALR20618.1S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (280 aa)
ALR20622.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1553 aa)
ALR20676.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
ALR20681.1Isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 4-oxalocrotonate tautomerase family. (83 aa)
ALR20709.1D-glycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (332 aa)
ALR22546.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (889 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (228 aa)
ALR22555.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)
ALR22557.1Hydroxyquinol 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
ALR20761.1Maleylacetate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
ALR20767.1Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa)
ALR20791.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (331 aa)
dapA-24-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (315 aa)
ALR22574.1Hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (487 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (610 aa)
ALR20857.1Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family. (321 aa)
ALR20858.12-dehydro-3-deoxyphosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (231 aa)
ALR20863.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (725 aa)
ALR20864.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
ALR20867.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
ALR20889.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
ALR20891.1Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (449 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (254 aa)
ALR21026.1Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (262 aa)
ALR21028.1Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
ALR22604.1uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (501 aa)
ALR21100.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
ALR21101.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
ALR21102.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
ALR21103.1methylmalonyl-CoA mutase; MDM; functions in conversion of succinate to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. (717 aa)
ALR21105.1acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (665 aa)
ALR21109.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (439 aa)
ALR21127.1Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
ALR21139.1Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (755 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (701 aa)
ALR21145.1F420-0--gamma-glutamyl ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
ALR21146.12-phospho-L-lactate transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
ALR21147.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
ALR21148.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
ALR21168.1Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
ALR21172.1Pyruvate phosphate dikinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (900 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa)
ALR21226.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
ALR22645.1Acylphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)
accDacetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (283 aa)
ALR21281.1E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
ALR21283.1Branched-chain alpha-keto acid dehydrogenase subunit E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (435 aa)
ALR21316.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
ALR21368.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
pckA-2Phosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (532 aa)
ALR21409.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
ALR22674.11-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (310 aa)
ALR21422.1Phosphoribosylpyrophosphate synthetase; Catalyzes the formation of PRPP from ATP and ribose 5-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribose-phosphate pyrophosphokinase family. (305 aa)
ALR22677.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
ALR21434.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (793 aa)
ALR21485.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
ALR21495.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
ALR21496.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
ALR21497.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
ALR21499.1Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (491 aa)
ALR21502.1Dienelactone hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
glnAForms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
ALR21563.1Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
ALR21584.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
ALR21599.1Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (462 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (358 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (424 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (191 aa)
sseA3-mercaptopyruvate sulfurtransferase; Catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
fumCClass II fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)
ALR21672.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (556 aa)
gltX-2glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (473 aa)
gltAType II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (428 aa)
ALR21722.1Class I fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (390 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
ALR21724.1Transketolase; Catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. (652 aa)
ALR21798.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
ALR21805.1LLM class F420-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
ALR21819.1Methylene-tetrahydromethanopterin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
ALR21828.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (722 aa)
ALR21829.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
ALR21839.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
ALR21840.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
ALR22751.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (399 aa)
ALR21907.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
cysQHypothetical protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (270 aa)
ALR21914.1beta-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
ALR21925.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (305 aa)
ALR21941.1Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (605 aa)
ALR21942.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
ALR21943.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
ALR21950.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
ALR22766.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (458 aa)
ALR21972.1Isocitrate lyase; Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; Derived by automated computational analysis using gene prediction method: Protein Homology. (530 aa)
ALR21978.15,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (308 aa)
ALR22013.1Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
ALR22014.1Ectoine hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
ectCL-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (137 aa)
ALR22016.1Diaminobutyrate--2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (435 aa)
ectAHypothetical protein; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. (143 aa)
ALR22052.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (282 aa)
ALR22085.1Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
ALR22086.1Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (416 aa)
sucASucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (931 aa)
sucDsuccinate--CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
ALR22092.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (262 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (266 aa)
ALR22185.1acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (159 aa)
ALR22186.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
ALR22188.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (380 aa)
Your Current Organism:
Sphingobium baderi
NCBI taxonomy Id: 1332080
Other names: CCM 7981, DSM 25433, S. baderi, Sphingobium baderi Kaur et al. 2013, strain LL03
Server load: low (10%) [HD]