STRINGSTRING
asd asd purA purA AQP46270.1 AQP46270.1 purC purC purS purS purQ purQ purF purF purM purM BW730_01020 BW730_01020 BW730_01170 BW730_01170 AQP46380.1 AQP46380.1 AQP46404.1 AQP46404.1 deoD deoD AQP46427.1 AQP46427.1 AQP46463.1 AQP46463.1 pyrC pyrC pyrB pyrB pyrR pyrR AQP46563.1 AQP46563.1 ndk ndk coaD coaD hisE hisE hisG hisG argC argC argJ argJ argB argB argR argR argH argH hisF hisF AQP46745.1 AQP46745.1 AQP46754.1 AQP46754.1 AQP46785.1 AQP46785.1 dapB dapB proB proB proA proA nadD nadD AQP46956.1 AQP46956.1 AQP46977.1 AQP46977.1 AQP46987.1 AQP46987.1 dut dut AQP47049.1 AQP47049.1 metXS metXS AQP47051.1 AQP47051.1 AQP47053.1 AQP47053.1 AQP47116.1 AQP47116.1 BW730_05915 BW730_05915 AQP47129.1 AQP47129.1 fmt fmt priA priA metK metK gmk gmk AQP47134.1 AQP47134.1 pyrD pyrD carB carB carA carA aroB aroB aroK aroK BW730_06080 BW730_06080 AQP47163.1 AQP47163.1 apt apt hisA hisA hisH hisH hisB hisB hisC hisC hisD hisD gltD gltD BW730_06370 BW730_06370 trpE trpE hisI hisI AQP47196.1 AQP47196.1 trpB trpB thrB thrB AQP47236.1 AQP47236.1 aroA aroA AQP49250.1 AQP49250.1 BW730_07090 BW730_07090 AQP47301.1 AQP47301.1 AQP47302.1 AQP47302.1 AQP47336.1 AQP47336.1 nrdR nrdR AQP47383.1 AQP47383.1 coaE coaE AQP47478.1 AQP47478.1 AQP47525.1 AQP47525.1 AQP47532.1 AQP47532.1 BW730_08660 BW730_08660 thyA thyA AQP47657.1 AQP47657.1 purE purE purK purK AQP47700.1 AQP47700.1 AQP49300.1 AQP49300.1 AQP49301.1 AQP49301.1 AQP47704.1 AQP47704.1 AQP47720.1 AQP47720.1 AQP47721.1 AQP47721.1 AQP47722.1 AQP47722.1 folD folD purH purH purN purN BW730_09920 BW730_09920 AQP49311.1 AQP49311.1 AQP47767.1 AQP47767.1 guaB guaB nnrD nnrD coaA coaA dapA dapA AQP47844.1 AQP47844.1 AQP47866.1 AQP47866.1 AQP47949.1 AQP47949.1 AQP49342.1 AQP49342.1 AQP47975.1 AQP47975.1 AQP47976.1 AQP47976.1 AQP47995.1 AQP47995.1 AQP48015.1 AQP48015.1 AQP48016.1 AQP48016.1 AQP48018.1 AQP48018.1 AQP48029.1 AQP48029.1 AQP48031.1 AQP48031.1 AQP48036.1 AQP48036.1 AQP48039.1 AQP48039.1 AQP48060.1 AQP48060.1 AQP48153.1 AQP48153.1 nadE nadE AQP48318.1 AQP48318.1 AQP48319.1 AQP48319.1 AQP48320.1 AQP48320.1 fhs fhs AQP48388.1 AQP48388.1 AQP48389.1 AQP48389.1 AQP48433.1 AQP48433.1 AQP49380.1 AQP49380.1 lgt lgt BW730_14785 BW730_14785 AQP48683.1 AQP48683.1 AQP48700.1 AQP48700.1 AQP49416.1 AQP49416.1 AQP48755.1 AQP48755.1 AQP48759.1 AQP48759.1 AQP48760.1 AQP48760.1 pheA pheA argG argG AQP48858.1 AQP48858.1 dcd dcd AQP48876.1 AQP48876.1 pyrE pyrE AQP49441.1 AQP49441.1 AQP49447.1 AQP49447.1 AQP49025.1 AQP49025.1 AQP49079.1 AQP49079.1 AQP49083.1 AQP49083.1 BW730_17910 BW730_17910 tilS tilS AQP49086.1 AQP49086.1 ftsH ftsH folE folE BW730_17940 BW730_17940 AQP49090.1 AQP49090.1 AQP49092.1 AQP49092.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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gene neighborhood
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asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (339 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (427 aa)
AQP46270.1NAD(P) transhydrogenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (291 aa)
purSPhosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (79 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (224 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (476 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
BW730_01020Cytochrome c nitrite reductase small subunit; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome c-552 family. (469 aa)
BW730_01170Phosphoglycerate dehydrogenase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (312 aa)
AQP46380.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
AQP46404.1Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. Belongs to the peptidase M17 family. (496 aa)
deoDPurine-nucleoside phosphorylase; Catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
AQP46427.1Diacylglycerol kinase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (171 aa)
AQP46463.1DNA (cytosine-5-)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (371 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (421 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (314 aa)
pyrRBifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (179 aa)
AQP46563.1Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. (444 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (135 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (158 aa)
hisEphosphoribosyl-ATP diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (287 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (343 aa)
argJBifunctional ornithine acetyltransferase/N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (383 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa)
argRAcetylornithine aminotransferase; Regulates arginine biosynthesis genes. (164 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa)
AQP46745.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
AQP46754.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (445 aa)
AQP46785.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (1113 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (246 aa)
proBGTPase ObgE; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (364 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (413 aa)
nadDNicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (222 aa)
AQP46956.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. (187 aa)
AQP46977.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
AQP46987.1Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (151 aa)
AQP47049.1Methionine biosynthesis protein MetW; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
metXSHomoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. (383 aa)
AQP47051.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
AQP47053.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
AQP47116.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
BW730_05915Methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1160 aa)
AQP47129.1rRNA cytosine-C5-methylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (442 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (303 aa)
priAHypothetical protein; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (635 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (395 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (184 aa)
AQP47134.1Orotidine-5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
pyrDDihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (349 aa)
carBCarbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1101 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (375 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (359 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (168 aa)
BW730_06080Chorismate synthase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
AQP47163.1Bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (757 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (179 aa)
hisAHaloacid dehalogenase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (203 aa)
hisBImidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
hisCHistidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (363 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (433 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (1508 aa)
BW730_06370Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (163 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (495 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (111 aa)
AQP47196.1TIGR03085 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (399 aa)
thrBHypothetical protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (290 aa)
AQP47236.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (417 aa)
AQP49250.1D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (404 aa)
BW730_07090Exodeoxyribonuclease V subunit alpha; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
AQP47301.1Hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (375 aa)
AQP47302.1Glutamine amidotransferase; Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
AQP47336.1Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (942 aa)
nrdRTranscriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (170 aa)
AQP47383.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (194 aa)
AQP47478.1Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa)
AQP47525.1Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
AQP47532.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (430 aa)
BW730_08660Elongation factor G; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (407 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (270 aa)
AQP47657.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (450 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (165 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (386 aa)
AQP47700.1NAD(P)H-quinone dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
AQP49300.1Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (292 aa)
AQP49301.1Phosphomannomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (554 aa)
AQP47704.1Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
AQP47720.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
AQP47721.1Adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
AQP47722.1Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (128 aa)
folDBifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
purHBifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (519 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (191 aa)
BW730_09920Glutamine-hydrolyzing GMP synthase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (309 aa)
AQP49311.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (100 aa)
AQP47767.1Inosine 5-monophosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (501 aa)
nnrDNAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. (462 aa)
coaAType I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa)
AQP47844.1Nicotinamidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
AQP47866.1Serine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
AQP47949.1Twin-arginine translocation pathway signal protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
AQP49342.1Nucleoside triphosphate pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
AQP47975.1Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (326 aa)
AQP47976.1Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (860 aa)
AQP47995.1Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
AQP48015.15-formyltetrahydrofolate cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (192 aa)
AQP48016.1FmdB family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
AQP48018.1Mechanosensitive ion channel protein MscL; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
AQP48029.1Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (336 aa)
AQP48031.1Glutamate synthase; Unknown function; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa)
AQP48036.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (366 aa)
AQP48039.1Permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa)
AQP48060.1O-succinylhomoserine (thiol)-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
AQP48153.1Aminodeoxychorismate/anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
nadENAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (696 aa)
AQP48318.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (131 aa)
AQP48319.1Cytosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
AQP48320.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
fhsFormate--tetrahydrofolate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the formate--tetrahydrofolate ligase family. (554 aa)
AQP48388.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
AQP48389.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
AQP48433.1NAD-dependent deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
AQP49380.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (342 aa)
BW730_14785Type I-E CRISPR-associated endoribonuclease Cas2; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa)
AQP48683.1Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (257 aa)
AQP48700.1L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (457 aa)
AQP49416.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
AQP48755.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
AQP48759.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (331 aa)
AQP48760.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family. (699 aa)
pheAPrephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
argGArgininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 2 subfamily. (476 aa)
AQP48858.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
dcddCTP deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (191 aa)
AQP48876.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (179 aa)
AQP49441.1Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
AQP49447.1GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
AQP49025.1Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
AQP49079.1Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)
AQP49083.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
BW730_17910Hypothetical protein; Incomplete; partial on complete genome; missing start and stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
tilSHypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (504 aa)
AQP49086.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (261 aa)
ftsHCell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (678 aa)
folEGTP cyclohydrolase I FolE; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
BW730_17940Dihydropteroate synthase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (118 aa)
AQP49090.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
AQP49092.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (202 aa)
Your Current Organism:
Tessaracoccus aquimaris
NCBI taxonomy Id: 1332264
Other names: JCM 19289, KACC 17540, T. aquimaris, Tessaracoccus aquimaris Tak et al. 2018, Tessaracoccus sp. NSG39, strain NSG39
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