STRINGSTRING
AQP46536.1 AQP46536.1 mutM mutM argH argH hisF hisF leuC leuC leuD leuD AQP46763.1 AQP46763.1 AQP46766.1 AQP46766.1 hemH hemH hemC hemC BW730_17940 BW730_17940 AQP46812.1 AQP46812.1 AQP46983.1 AQP46983.1 AQP47004.1 AQP47004.1 AQP47015.1 AQP47015.1 AQP47121.1 AQP47121.1 AQP47134.1 AQP47134.1 aroB aroB AQP47148.1 AQP47148.1 AQP47149.1 AQP47149.1 hisH hisH hisB hisB BW730_06370 BW730_06370 trpE trpE trpB trpB AQP47214.1 AQP47214.1 kgd kgd AQP47259.1 AQP47259.1 AQP47325.1 AQP47325.1 cobD cobD ilvD ilvD AQP47383.1 AQP47383.1 AQP47385.1 AQP47385.1 AQP47445.1 AQP47445.1 AQP47457.1 AQP47457.1 AQP47458.1 AQP47458.1 AQP47459.1 AQP47459.1 AQP47465.1 AQP47465.1 AQP47475.1 AQP47475.1 BW730_08660 BW730_08660 AQP47625.1 AQP47625.1 purK purK nnrD nnrD dapA dapA ilvA ilvA eno eno AQP48067.1 AQP48067.1 ispF ispF AQP48081.1 AQP48081.1 AQP48153.1 AQP48153.1 cynS cynS fumC fumC hemH-2 hemH-2 AQP48324.1 AQP48324.1 AQP48435.1 AQP48435.1 AQP48674.1 AQP48674.1 AQP48694.1 AQP48694.1 AQP48700.1 AQP48700.1 pheA pheA menB menB AQP48832.1 AQP48832.1 deoC deoC AQP48876.1 AQP48876.1 AQP48883.1 AQP48883.1 AQP48930.1 AQP48930.1 AQP48947.1 AQP48947.1 AQP48954.1 AQP48954.1 AQP48958.1 AQP48958.1 AQP48982.1 AQP48982.1 mgsA mgsA AQP49016.1 AQP49016.1 nth nth AQP49051.1 AQP49051.1 AQP46209.1 AQP46209.1 AQP46226.1 AQP46226.1 AQP46278.1 AQP46278.1 AQP46279.1 AQP46279.1 aspA aspA AQP46330.1 AQP46330.1 menC menC AQP46430.1 AQP46430.1 AQP46517.1 AQP46517.1 AQP46535.1 AQP46535.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AQP46536.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
mutMRibonuclease III; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (279 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (465 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa)
AQP46763.1Keto-deoxy-phosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
AQP46766.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (369 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (541 aa)
BW730_17940Dihydropteroate synthase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (118 aa)
AQP46812.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (321 aa)
AQP46983.1Carbonic anhydrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
AQP47004.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
AQP47015.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
AQP47121.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (102 aa)
AQP47134.1Orotidine-5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (359 aa)
AQP47148.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
AQP47149.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (203 aa)
hisBImidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
BW730_06370Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (163 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (495 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (399 aa)
AQP47214.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
kgdAlpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. (1276 aa)
AQP47259.1Ketose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
AQP47325.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
cobDCobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (313 aa)
ilvDCardiolipin synthase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (613 aa)
AQP47383.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
AQP47385.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the uroporphyrinogen decarboxylase family. (320 aa)
AQP47445.1Low specificity L-threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
AQP47457.1Ethanolamine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the EutC family. (301 aa)
AQP47458.1Ethanolamine ammonia lyase large subunit; With EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
AQP47459.1Ethanolamine utilization protein EutA; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
AQP47465.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
AQP47475.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (805 aa)
BW730_08660Elongation factor G; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (407 aa)
AQP47625.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (386 aa)
nnrDNAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. (462 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (295 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (430 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
AQP48067.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (153 aa)
AQP48081.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
AQP48153.1Aminodeoxychorismate/anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
cynSCyanase; Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide; Belongs to the cyanase family. (147 aa)
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
hemH-2Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (349 aa)
AQP48324.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
AQP48435.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
AQP48674.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
AQP48694.1Bleomycin resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (120 aa)
AQP48700.1L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (457 aa)
pheAPrephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
menB1,4-dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (299 aa)
AQP48832.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (228 aa)
AQP48876.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
AQP48883.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa)
AQP48930.1Class II fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (341 aa)
AQP48947.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (560 aa)
AQP48954.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (305 aa)
AQP48958.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (184 aa)
AQP48982.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (790 aa)
mgsAMethylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (146 aa)
AQP49016.1dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (331 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (223 aa)
AQP49051.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
AQP46209.1Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (528 aa)
AQP46226.1Phosphoenolpyruvate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
AQP46278.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
AQP46279.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
aspAAspartate ammonia-lyase; Catalyzes the formation of fumarate from aspartate; Derived by automated computational analysis using gene prediction method: Protein Homology. (493 aa)
AQP46330.1Molybdenum cofactor biosynthesis protein C; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
menCO-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (316 aa)
AQP46430.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (618 aa)
AQP46517.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
AQP46535.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
Your Current Organism:
Tessaracoccus aquimaris
NCBI taxonomy Id: 1332264
Other names: JCM 19289, KACC 17540, T. aquimaris, Tessaracoccus aquimaris Tak et al. 2018, Tessaracoccus sp. NSG39, strain NSG39
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