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dnaX dnaX glgC glgC AKL17_4563 AKL17_4563 rph rph dnaQ dnaQ AKL17_4310 AKL17_4310 AKL17_4308 AKL17_4308 AKL17_4307 AKL17_4307 AKL17_4299 AKL17_4299 AKL17_4298 AKL17_4298 AKL17_4214 AKL17_4214 pnp pnp dinB-2 dinB-2 AKL17_4141 AKL17_4141 AKL17_3325 AKL17_3325 dnaE2 dnaE2 AKL17_4062 AKL17_4062 dinB dinB cysC cysC AKL17_1311 AKL17_1311 AKL17_1312 AKL17_1312 AKL17_1345 AKL17_1345 AKL17_1346 AKL17_1346 rpoA rpoA rpoC rpoC rpoB rpoB rpoZ rpoZ AKL17_0312 AKL17_0312 AKL17_0309 AKL17_0309 nadD nadD mobA mobA AKL17_0113 AKL17_0113 AKL17_1935 AKL17_1935 AKL17_2106 AKL17_2106 glmU glmU AKL17_2670 AKL17_2670 AKL17_2771 AKL17_2771 AKL17_3008 AKL17_3008 AKL17_3009 AKL17_3009 polA polA AKL17_3157 AKL17_3157 AKL17_3236 AKL17_3236 AKL17_0002 AKL17_0002 AKL17_1515 AKL17_1515 AKL17_1564 AKL17_1564 AKL17_1565 AKL17_1565 selO selO AKL17_1718 AKL17_1718 coaD coaD AKL17_1895 AKL17_1895 AKL17_1908 AKL17_1908 AKL17_0951 AKL17_0951 AKL17_0942 AKL17_0942 AKL17_0810 AKL17_0810 AKL17_0645 AKL17_0645 glnD glnD AKL17_4726 AKL17_4726
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dnaXDNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (448 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (424 aa)
AKL17_4563CCA-adding enzyme; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (380 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (237 aa)
dnaQDNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (231 aa)
AKL17_43103-deoxy-manno-octulosonate cytidylyltransferase. (270 aa)
AKL17_4308UTP--glucose-1-phosphate uridylyltransferase. (90 aa)
AKL17_4307UTP-glucose-1-phosphate uridylyltransferase. (202 aa)
AKL17_4299RNA polymerase sigma-54 factor. (336 aa)
AKL17_4298Hypothetical protein. (93 aa)
AKL17_4214Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (174 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (710 aa)
dinB-2DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (417 aa)
AKL17_4141Hypothetical protein. (490 aa)
AKL17_3325Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. (476 aa)
dnaE2DNA polymerase III alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1059 aa)
AKL17_4062Hypothetical protein. (464 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (375 aa)
cysCBifunctional sulfate adenylyltransferase/adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (568 aa)
AKL17_1311ADP-glucose pyrophosphorylase. (80 aa)
AKL17_1312ADP-glucose pyrophosphorylase. (304 aa)
AKL17_1345Diguanylate cyclase. (303 aa)
AKL17_1346Sensor diguanylate cyclase. (94 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (338 aa)
rpoCDNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1414 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1430 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (119 aa)
AKL17_0312Putative exonuclease. (690 aa)
AKL17_0309Hypothetical protein. (641 aa)
nadDNicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (209 aa)
mobAMolybdopterin-guanine dinucleotide biosynthesis protein MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (206 aa)
AKL17_0113Cas2 family CRISPR-associated protein. (318 aa)
AKL17_1935Phosphatidate cytidylyltransferase; Belongs to the CDS family. (294 aa)
AKL17_2106Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] (930 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (449 aa)
AKL17_2670DNA polymerase III subunit delta'. (382 aa)
AKL17_2771Response regulator receiver modulated diguanylate cyclase/phosphodiesterase. (464 aa)
AKL17_3008DNA primase. (255 aa)
AKL17_3009DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (400 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (946 aa)
AKL17_3157DNA ligase D. (812 aa)
AKL17_3236Riboflavin biosynthesis protein RibF. (260 aa)
AKL17_0002Bifunctional cobinamide kinase/cobinamide phosphate guanyltransferase protein CobP. (184 aa)
AKL17_1515Diguanylate cyclase precursor. (437 aa)
AKL17_1564RNA polymerase sigma-54 factor. (161 aa)
AKL17_1565RNA polymerase sigma-54 factor. (264 aa)
selOHypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family. (481 aa)
AKL17_1718DNA polymerase III subunit chi. (151 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (167 aa)
AKL17_1895Molybdopterin-guanine dinucleotide biosynthesis protein A-like protein. (179 aa)
AKL17_1908Protein YicC. (314 aa)
AKL17_0951Two-component system, PleD-related family,response regulator. (289 aa)
AKL17_0942FMN adenylyltransferase / riboflavin kinase; Belongs to the ribF family. (308 aa)
AKL17_0810DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (372 aa)
AKL17_0645DNA polymerase III subunit alpha. (1168 aa)
glnDPII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (937 aa)
AKL17_4726DNA polymerase III subunits gamma and tau. (91 aa)
Your Current Organism:
Defluviimonas alba
NCBI taxonomy Id: 1335048
Other names: CGMCC 1.12518, D. alba, Defluviimonas alba Pan et al. 2015, LMG 27406, LMG:27406, Rhodobacter sp. b45, Rhodobacter sp. cai42, strain cai42
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