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| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa) |
| | AKL17_0120 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa) |
| | AKL17_0119 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (384 aa) |
| | AKL17_0092 | Pyridoxal-5'-phosphate-dependent protein subunit beta. (374 aa) |
| | AKL17_0066 | precorrin-3B synthase. (133 aa) |
| | AKL17_0065 | precorrin-3B synthase. (248 aa) |
| | AKL17_0047 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa) |
| | AKL17_0034 | D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding subunit. (319 aa) |
| | AKL17_0033 | Dihydrodipicolinate synthetase; Belongs to the DapA family. (299 aa) |
| | AKL17_0018 | Homocysteine S-methyltransferase protein. (293 aa) |
| | AKL17_2661 | Serine O-acetyltransferase. (268 aa) |
| | rpsF | Methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; Binds together with S18 to 16S ribosomal RNA. (538 aa) |
| | AKL17_2507 | Ferredoxin. (681 aa) |
| | fabH | fabH-2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (325 aa) |
| | plsX | Putative glycerol-3-phosphate acyltransferase PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (366 aa) |
| | AKL17_2494 | Radical SAM domain protein. (64 aa) |
| | AKL17_2493 | Radical SAM domain-containing protein. (252 aa) |
| | metAA | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (311 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa) |
| | AKL17_2447 | 3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (420 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa) |
| | AKL17_2399 | Carboxyl transferase. (510 aa) |
| | AKL17_2378 | Kynureninase. (351 aa) |
| | AKL17_2369 | Acetylornithine deacetylase. (388 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (327 aa) |
| | AKL17_2335 | Phosphoglycolate phosphatase. (222 aa) |
| | AKL17_2331 | methylcrotonoyl-CoA carboxylase subunit beta. (534 aa) |
| | argH-2 | Argininosuccinate lyase-2. (499 aa) |
| | AKL17_2245 | N-carbamoyl-L-amino acid hydrolase. (415 aa) |
| | AKL17_2189 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (349 aa) |
| | AKL17_2113 | Acetolactate synthase 3 regulatory subunit. (186 aa) |
| | lipA | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (319 aa) |
| | AKL17_2020 | Cysteine synthase A. (343 aa) |
| | AKL17_1999 | acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa) |
| | AKL17_1998 | acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (162 aa) |
| | AKL17_1987 | Allantoate amidohydrolase. (267 aa) |
| | AKL17_1980 | Omega amino acid--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (119 aa) |
| | fabZ | 3-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (163 aa) |
| | AKL17_1921 | Putative alpha-isopropylmalate/homocitrate synthase family transferase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (550 aa) |
| | AKL17_1888 | Usg family protein. (107 aa) |
| | AKL17_1833 | Beta ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (403 aa) |
| | AKL17_1832 | Phosphopantetheine-binding. (88 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (421 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (376 aa) |
| | AKL17_1756 | Sulfite reductase. (554 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (342 aa) |
| | AKL17_1645 | D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein. (331 aa) |
| | AKL17_1643 | Tartrate dehydrogenase. (358 aa) |
| | AKL17_1612 | Putative NADPH:quinone oxidoreductase protein. (332 aa) |
| | AKL17_1562 | Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (387 aa) |
| | AKL17_1456 | Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (455 aa) |
| | AKL17_1438 | Enoyl- reductase. (273 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (503 aa) |
| | trpC | Indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (272 aa) |
| | AKL17_1381 | malonyl-CoA decarboxylase. (434 aa) |
| | AKL17_1354 | 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. (301 aa) |
| | AKL17_1350 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (578 aa) |
| | AKL17_1253 | Hypothetical protein. (244 aa) |
| | argD | Acetylornithine transaminase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (389 aa) |
| | AKL17_1187 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (308 aa) |
| | AKL17_1171 | Putative acetyltransferase. (155 aa) |
| | AKL17_1166 | Hypothetical protein. (232 aa) |
| | carB | Carbamoyl phosphate synthase large subunit; Belongs to the CarB family. (1109 aa) |
| | AKL17_1142 | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP; Belongs to the PRA-CH family. (127 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (437 aa) |
| | carA | Carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (388 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (340 aa) |
| | AKL17_2702 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (318 aa) |
| | hisC-2 | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (355 aa) |
| | AKL17_2752 | Homoserine dehydrogenase. (428 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (372 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (181 aa) |
| | AKL17_2813 | Aminodeoxychorismate synthase. (325 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (195 aa) |
| | hisH | Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (212 aa) |
| | AKL17_2848 | 1--5-[methylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family. (147 aa) |
| | AKL17_2849 | 1--5-[methylideneamino] imidazole-4-carboxamide isomerase; Belongs to the HisA/HisF family. (94 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase. (103 aa) |
| | AKL17_2856 | O-acetylhomoserine aminocarboxypropyltransferase/O-acetylserine sulfhydrylase. (426 aa) |
| | AKL17_2915 | GNAT family acetyltransferase. (161 aa) |
| | AKL17_2986 | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1258 aa) |
| | AKL17_2987 | Enoyl-[acyl-carrier-protein] reductase. (254 aa) |
| | AKL17_3022 | Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1146 aa) |
| | AKL17_3029 | 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (288 aa) |
| | AKL17_3037 | Histidinol-phosphate aminotransferase. (182 aa) |
| | AKL17_3087 | Allantoate amidohydrolase. (402 aa) |
| | AKL17_3103 | Phosphoserine phosphatase SerB. (299 aa) |
| | AKL17_3210 | Acetylornithine deacetylase. (373 aa) |
| | AKL17_3217 | 3-isopropylmalate dehydrogenase. (343 aa) |
| | AKL17_3222 | Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa) |
| | AKL17_3257 | Dihydrodipicolinate synthase. (311 aa) |
| | AKL17_3286 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (592 aa) |
| | AKL17_3326 | Nucleotide sugar dehydrogenase. (388 aa) |
| | AKL17_3385 | Prephenate dehydrogenase. (237 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa) |
| | AKL17_3496 | Aspartate kinase; Belongs to the aspartokinase family. (419 aa) |
| | mtnP | 5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (291 aa) |
| | AKL17_3514 | Threonine synthase. (463 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (296 aa) |
| | AKL17_3548 | Chorismate mutase family protein. (102 aa) |
| | AKL17_3623 | Succinyl-diaminopimelate desuccinylase. (425 aa) |
| | AKL17_3718 | 4-hydroxyphenylpyruvate dioxygenase. (626 aa) |
| | AKL17_3719 | Putative shikimate/quinate 5-dehydrogenase. (281 aa) |
| | AKL17_3738 | Glutamate synthase domain-containing protein; Belongs to the glutamate synthase family. (547 aa) |
| | AKL17_3819 | Short-chain dehydrogenase/reductase SDR. (259 aa) |
| | AKL17_3833 | Dihydrodipicolinate synthetase family; Belongs to the DapA family. (307 aa) |
| | AKL17_3835 | Acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase. (406 aa) |
| | AKL17_3842 | Allantoate amidohydrolase. (434 aa) |
| | AKL17_3879 | Dihydrodipicolinate synthase; Belongs to the DapA family. (311 aa) |
| | dapE | Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (393 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (279 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (269 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (369 aa) |
| | AKL17_4241 | Hypothetical protein. (104 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (279 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (367 aa) |
| | ilvE | Branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (289 aa) |
| | AKL17_4286 | Glutamate synthase subunit alpha. (1512 aa) |
| | AKL17_4289 | Putative oxidoreductase. (479 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (456 aa) |
| | AKL17_4335 | Carboxyl transferase. (535 aa) |
| | AKL17_4454 | propionyl-CoA carboxylase. (89 aa) |
| | AKL17_4455 | propionyl-CoA carboxylase. (150 aa) |
| | AKL17_4456 | propionyl-CoA carboxylase. (308 aa) |
| | AKL17_4461 | 3-methylcrotonoyl-CoA carboxylase beta subunit. (535 aa) |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (278 aa) |
| | AKL17_4553 | Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase / branched chain amino acid aminotransferase. (302 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (407 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (340 aa) |
| | AKL17_4704 | FolC bifunctional protein. (146 aa) |
| | AKL17_4705 | FolC bifunctional protein. (282 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (317 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (577 aa) |
| | AKL17_4721 | Alcohol dehydrogenase, zinc-containing. (331 aa) |
| | AKL17_4741 | Prephenate dehydratase. (285 aa) |
| | AKL17_1059 | Hypothetical protein; Belongs to the AB hydrolase superfamily. MetX family. (277 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa) |
| | AKL17_0923 | Cyclohexadienyl dehydrogenase. (304 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (386 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (448 aa) |
| | trpF | N-anthranilate isomerase; Belongs to the TrpF family. (211 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (410 aa) |
| | trpA | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (263 aa) |
| | AKL17_0875 | 3-hydroxydecanoyl- dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (170 aa) |
| | AKL17_0874 | 3-oxoacyl- synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (409 aa) |
| | AKL17_0873 | Enoyl-[acyl-carrier-protein] reductase. (262 aa) |
| | AKL17_0756 | Hypothetical protein. (334 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (534 aa) |
| | kdsA | 3-deoxy-8-phosphooctulonate synthase; Belongs to the KdsA family. (277 aa) |
| | AKL17_0649 | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (223 aa) |
| | hisS | histidyl-tRNA synthetase. (868 aa) |
| | AKL17_0601 | Branched-chain-amino-acid transaminase. (287 aa) |
| | AKL17_0592 | Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (270 aa) |
| | AKL17_0547 | Glutamine synthetase. (930 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (297 aa) |
| | acpS | 4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (144 aa) |
| | AKL17_0372 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (195 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (290 aa) |
| | AKL17_0251 | Glutamate synthase large subunit 2 protein; Belongs to the glutamate synthase family. (442 aa) |
| | AKL17_0250 | Formyl-methanofuran dehydrogenase. (229 aa) |
| | AKL17_0232 | Aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (458 aa) |
| | AKL17_0230 | SMP-30/gluconolaconase/LRE domain-containing protein. (285 aa) |
| | AKL17_0224 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (581 aa) |
| | AKL17_0207 | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (221 aa) |
| | AKL17_0201 | Hypothetical protein. (48 aa) |
| | AKL17_0200 | glyA-3. (396 aa) |
| | AKL17_0197 | Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (457 aa) |
| | accA | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa) |
| | argH | Argininosuccinate lyase. (471 aa) |
| | leuD | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) |
| | leuC | Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (480 aa) |
