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AKL17_0047 AKL17_0047 AKL17_0126 AKL17_0126 AKL17_0160 AKL17_0160 AKL17_0161 AKL17_0161 AKL17_0200 AKL17_0200 AKL17_0206 AKL17_0206 AKL17_0207 AKL17_0207 AKL17_0211 AKL17_0211 cbbL cbbL AKL17_0241 AKL17_0241 AKL17_0243 AKL17_0243 purU purU acsA acsA AKL17_0387 AKL17_0387 AKL17_0458 AKL17_0458 AKL17_0577 AKL17_0577 AKL17_0582 AKL17_0582 AKL17_0627 AKL17_0627 AKL17_0706 AKL17_0706 AKL17_0822 AKL17_0822 AKL17_0823 AKL17_0823 AKL17_0824 AKL17_0824 AKL17_0910 AKL17_0910 AKL17_0912 AKL17_0912 AKL17_0943 AKL17_0943 AKL17_0997 AKL17_0997 AKL17_1163 AKL17_1163 AKL17_1460 AKL17_1460 AKL17_1462 AKL17_1462 AKL17_1643 AKL17_1643 AKL17_1644 AKL17_1644 AKL17_1681 AKL17_1681 AKL17_1969 AKL17_1969 glcB glcB AKL17_2054 AKL17_2054 AKL17_2099 AKL17_2099 AKL17_2335 AKL17_2335 AKL17_2390 AKL17_2390 AKL17_2393 AKL17_2393 AKL17_2399 AKL17_2399 AKL17_2489 AKL17_2489 AKL17_2648 AKL17_2648 purU-2 purU-2 AKL17_2769 AKL17_2769 AKL17_2795 AKL17_2795 gcvP gcvP gcvH gcvH AKL17_2921 AKL17_2921 AKL17_3039 AKL17_3039 AKL17_3096 AKL17_3096 AKL17_3139 AKL17_3139 AKL17_3141 AKL17_3141 AKL17_3142 AKL17_3142 AKL17_3189 AKL17_3189 AKL17_3202 AKL17_3202 AKL17_3217 AKL17_3217 AKL17_3271 AKL17_3271 AKL17_3427 AKL17_3427 glyA glyA AKL17_3598 AKL17_3598 AKL17_3626 AKL17_3626 mdh mdh AKL17_3637 AKL17_3637 AKL17_3640 AKL17_3640 AKL17_3707 AKL17_3707 AKL17_4339 AKL17_4339 AKL17_4463 AKL17_4463 AKL17_4474 AKL17_4474 AKL17_4662 AKL17_4662
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKL17_0047D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa)
AKL17_0126Beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
AKL17_0160acetoacetyl-CoA reductase. (240 aa)
AKL17_0161acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
AKL17_0200glyA-3. (396 aa)
AKL17_0206Putative catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (705 aa)
AKL17_0207Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (221 aa)
AKL17_0211Ribulose 1,5-bisphosphate carboxylase small subunit. (128 aa)
cbbLRibulose bisophosphate carboxylase; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site; Belongs to the RuBisCO large chain family. Type I subfamily. (485 aa)
AKL17_0241Glycine cleavage system T protein; Belongs to the GcvT family. (793 aa)
AKL17_0243Sarcosine oxidase alpha subunit; Belongs to the GcvT family. (375 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (294 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (684 aa)
AKL17_0387acyl-CoA dehydrogenase domain-containing protein. (556 aa)
AKL17_0458Phosphoglycolate phosphatase. (223 aa)
AKL17_0577Glutamine synthetase. (454 aa)
AKL17_0582Aminomethyltransferase protein; Belongs to the GcvT family. (350 aa)
AKL17_0627Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)
AKL17_0706D-isomer specific 2-hydroxyacid dehydrogenase family protein. (174 aa)
AKL17_0822Formate dehydrogenase subunit gamma. (156 aa)
AKL17_0823NAD dependent formate dehydrogenase, beta subunit. (509 aa)
AKL17_0824NAD-dependent formate dehydrogenase, alpha subunit. (959 aa)
AKL17_0910methylmalonyl-CoA mutase large subunit. (656 aa)
AKL17_0912crotonyl-CoA reductase. (430 aa)
AKL17_0943MaoC domain-containing protein dehydratase. (149 aa)
AKL17_0997D-2-hydroxyacid dehydrogenase protein. (310 aa)
AKL17_1163methylmalonyl-CoA epimerase. (134 aa)
AKL17_1460Glutamine synthetase-5. (457 aa)
AKL17_1462Glutamine synthetase-4. (443 aa)
AKL17_1643Tartrate dehydrogenase. (358 aa)
AKL17_1644Hydroxypyruvate reductase. (443 aa)
AKL17_1681Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (923 aa)
AKL17_1969Citrate -synthase; Belongs to the citrate synthase family. (431 aa)
glcBMalate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (720 aa)
AKL17_2054Hypothetical protein. (269 aa)
AKL17_2099Catalase. (488 aa)
AKL17_2335Phosphoglycolate phosphatase. (222 aa)
AKL17_2390methylmalonyl-CoA mutase. (714 aa)
AKL17_2393propionyl-CoA carboxylase alpha subunit. (666 aa)
AKL17_2399Carboxyl transferase. (510 aa)
AKL17_2489KHG/KDPG aldolase. (151 aa)
AKL17_2648L-glutamine synthetase. (468 aa)
purU-2Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (294 aa)
AKL17_2769HAD-superfamily hydrolase, subfamily IA, variant 1 family protein. (242 aa)
AKL17_2795Dihydrolipoamide dehydrogenase. (465 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (945 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (119 aa)
AKL17_2921Glycine cleavage T protein. (374 aa)
AKL17_3039Serine--glyoxylate transaminase. (399 aa)
AKL17_30963-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
AKL17_3139Glycolate oxidase, iron-sulfur subunit. (427 aa)
AKL17_3141FAD linked oxidase domain-containing protein. (364 aa)
AKL17_3142Glycolate dehydrogenase, subunit GlcD. (477 aa)
AKL17_3189Hydroxypyruvate reductase. (221 aa)
AKL17_3202Dehydrogenase. (308 aa)
AKL17_32173-isopropylmalate dehydrogenase. (343 aa)
AKL17_3271Hypothetical protein. (176 aa)
AKL17_3427acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa)
AKL17_3598Citrate -lyase; Belongs to the HpcH/HpaI aldolase family. (318 aa)
AKL17_3626Dihydrolipoamide dehydrogenase. (462 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
AKL17_3637Citrate -lyase; Belongs to the HpcH/HpaI aldolase family. (290 aa)
AKL17_3640MaoC domain-containing protein. (343 aa)
AKL17_3707D-2-hydroxyacid dehydrogenase protein. (310 aa)
AKL17_4339Citrate synthase. (264 aa)
AKL17_4463Biotin carboxylase. (489 aa)
AKL17_4474AMP-dependent synthetase and ligase. (645 aa)
AKL17_4662acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
Your Current Organism:
Defluviimonas alba
NCBI taxonomy Id: 1335048
Other names: CGMCC 1.12518, D. alba, Defluviimonas alba Pan et al. 2015, LMG 27406, LMG:27406, Rhodobacter sp. b45, Rhodobacter sp. cai42, strain cai42
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