STRINGSTRING
rplF rplF rpsH rpsH rpsZ rpsZ rplE rplE rplN rplN rpsQ rpsQ rpmC rpmC GCA_000518825_00499 GCA_000518825_00499 rplP rplP GCA_000518825_00501 GCA_000518825_00501 rpsC rpsC rplV rplV rpsS rpsS rplB rplB rplW rplW rplD rplD GCA_000518825_00508 GCA_000518825_00508 rplC rplC rpsJ rpsJ CK556_00655 CK556_00655 atpD atpD atpG atpG GCA_000518825_00529 GCA_000518825_00529 GCA_000518825_00530 GCA_000518825_00530 atpA atpA GCA_000518825_00532 GCA_000518825_00532 atpH atpH atpF atpF atpE atpE GCA_000518825_00536 GCA_000518825_00536 GCA_000518825_00537 GCA_000518825_00537 CK556_00620 CK556_00620 GCA_000518825_00540 GCA_000518825_00540 upp upp glyA glyA rpmG-2 rpmG-2 GCA_000518825_00580 GCA_000518825_00580 GCA_000518825_00581 GCA_000518825_00581 cysS cysS rplI rplI rpsR rpsR rpsF rpsF pth pth CK556_00450 CK556_00450 GCA_000518825_00601 GCA_000518825_00601 GCA_000518825_00602 GCA_000518825_00602 GCA_000518825_00603 GCA_000518825_00603 GCA_000518825_00604 GCA_000518825_00604 purA purA GCA_000518825_00624 GCA_000518825_00624 CK556_00400 CK556_00400 CK556_00390 CK556_00390 GCA_000518825_00630 GCA_000518825_00630 GCA_000518825_00635 GCA_000518825_00635 CK556_00375 CK556_00375 proC proC ackA ackA GCA_000518825_00662 GCA_000518825_00662 pta pta GCA_000518825_00680 GCA_000518825_00680 GCA_000518825_00681 GCA_000518825_00681 metG metG GCA_000518825_00683 GCA_000518825_00683 GCA_000518825_00729 GCA_000518825_00729 lysS lysS GCA_000518825_00747 GCA_000518825_00747 serS serS GCA_000518825_00749 GCA_000518825_00749 GCA_000518825_00829 GCA_000518825_00829 tmk tmk GCA_000518825_00860 GCA_000518825_00860 nadE nadE GCA_000518825_00862 GCA_000518825_00862 rplS rplS rpsP rpsP GCA_000518825_00927 GCA_000518825_00927 GCA_000518825_00928 GCA_000518825_00928 argS argS frr frr GCA_000518825_00931 GCA_000518825_00931 pyrH pyrH GCA_000518825_00933 GCA_000518825_00933 tsf tsf GCA_000518825_00936 GCA_000518825_00936 rpsB rpsB GCA_000518825_00938 GCA_000518825_00938 def def thiI thiI rpsD rpsD tyrS tyrS GCA_000518825_00989 GCA_000518825_00989 GCA_000518825_00990 GCA_000518825_00990 GCA_000518825_00991 GCA_000518825_00991 GCA_000518825_00992 GCA_000518825_00992 GCA_000518825_00993 GCA_000518825_00993 CK556_03295 CK556_03295 GCA_000518825_00995 GCA_000518825_00995 CK556_03300 CK556_03300 rplL rplL rplJ rplJ rplA rplA GCA_000518825_01044 GCA_000518825_01044 rplK rplK GCA_000518825_01084 GCA_000518825_01084 gltX gltX GCA_000518825_01086 GCA_000518825_01086 GCA_000518825_01087 GCA_000518825_01087 GCA_000518825_01088 GCA_000518825_01088 GCA_000518825_01091 GCA_000518825_01091 pyrG pyrG GCA_000518825_01093 GCA_000518825_01093 GCA_000518825_01094 GCA_000518825_01094 rpmE rpmE GCA_000518825_01121 GCA_000518825_01121 prfA prfA rpsL rpsL rpsG rpsG GCA_000518825_01142 GCA_000518825_01142 GCA_000518825_01143 GCA_000518825_01143 fusA fusA GCA_000518825_01145 GCA_000518825_01145 GCA_000518825_01146 GCA_000518825_01146 tuf tuf GCA_000518825_01182 GCA_000518825_01182 GCA_000518825_01183 GCA_000518825_01183 alaS alaS CK556_02605 CK556_02605 hpt hpt typA typA lepA lepA GCA_000518825_01221 GCA_000518825_01221 proS proS GCA_000518825_01225 GCA_000518825_01225 GCA_000518825_01230 GCA_000518825_01230 asnS asnS GCA_000518825_01250 GCA_000518825_01250 leuS leuS GCA_000518825_01252 GCA_000518825_01252 GCA_000518825_01253 GCA_000518825_01253 rpsI rpsI rplM rplM rplU rplU rpmA rpmA GCA_000518825_01344 GCA_000518825_01344 CK556_02475 CK556_02475 GCA_000518825_01378 GCA_000518825_01378 thyA thyA fmt fmt GCA_000518825_01403 GCA_000518825_01403 efp efp GCA_000518825_01406 GCA_000518825_01406 CK556_01690 CK556_01690 pheS pheS GCA_000518825_01476 GCA_000518825_01476 GCA_000518825_01477 GCA_000518825_01477 GCA_000518825_01478 GCA_000518825_01478 GCA_000518825_01479 GCA_000518825_01479 pheT pheT rpmF rpmF GCA_000518825_01492 GCA_000518825_01492 GCA_000518825_01493 GCA_000518825_01493 GCA_000518825_01494 GCA_000518825_01494 GCA_000518825_01495 GCA_000518825_01495 ileS ileS GCA_000518825_01497 GCA_000518825_01497 GCA_000518825_01499 GCA_000518825_01499 GCA_000518825_01498 GCA_000518825_01498 CK556_02175 CK556_02175 GCA_000518825_01500 GCA_000518825_01500 thrS thrS GCA_000518825_00019 GCA_000518825_00019 GCA_000518825_00020 GCA_000518825_00020 infC infC rpmI rpmI rplT rplT trpS trpS GCA_000518825_00043 GCA_000518825_00043 CK556_01080 CK556_01080 CK556_01145 CK556_01145 smpB smpB CK556_01240 CK556_01240 CK556_01390 CK556_01390 glyQS glyQS GCA_000518825_00200 GCA_000518825_00200 GCA_000518825_00201 GCA_000518825_00201 apt apt coaE coaE GCA_000518825_00232 GCA_000518825_00232 CK556_01540 CK556_01540 rpsO rpsO infB infB CK556_01855 CK556_01855 guaA guaA CK556_01885 CK556_01885 GCA_000518825_00373 GCA_000518825_00373 GCA_000518825_00374 GCA_000518825_00374 GCA_000518825_00375 GCA_000518825_00375 GCA_000518825_00376 GCA_000518825_00376 valS valS GCA_000518825_00378 GCA_000518825_00378 GCA_000518825_00379 GCA_000518825_00379 rpsU rpsU GCA_000518825_00395 GCA_000518825_00395 GCA_000518825_00396 GCA_000518825_00396 aspS aspS hisS hisS rpsT rpsT mtnN mtnN GCA_000518825_00410 GCA_000518825_00410 nadD nadD rpmG rpmG folD folD GCA_000518825_00441 GCA_000518825_00441 gatB gatB CK556_00880 CK556_00880 rplQ rplQ rpsK rpsK GCA_000518825_00478 GCA_000518825_00478 rpsM rpsM rpmJ rpmJ infA infA adk adk rplO rplO rpsE rpsE rplR rplR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rplFUnannotated protein; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (180 aa)
rpsHUnannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (128 aa)
rpsZUnannotated protein; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (60 aa)
rplEUnannotated protein; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (180 aa)
rplNUnannotated protein; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rpsQUnannotated protein; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (85 aa)
rpmCUnannotated protein; Belongs to the universal ribosomal protein uL29 family. (137 aa)
GCA_000518825_00499Unannotated protein. (35 aa)
rplPUnannotated protein; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (40 aa)
GCA_000518825_00501Unannotated protein. (39 aa)
rpsCUnannotated protein; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (46 aa)
rplVUnannotated protein; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (112 aa)
rpsSUnannotated protein; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (30 aa)
rplBUnannotated protein; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (207 aa)
rplWUnannotated protein; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (94 aa)
rplDUnannotated protein; Forms part of the polypeptide exit tunnel. (70 aa)
GCA_000518825_00508Unannotated protein. (39 aa)
rplCUnannotated protein; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (238 aa)
rpsJUnannotated protein; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
CK556_00655Unannotated protein. (59 aa)
atpDUnannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (479 aa)
atpGUnannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (148 aa)
GCA_000518825_00529Unannotated protein. (77 aa)
GCA_000518825_00530Unannotated protein. (197 aa)
atpAUnannotated protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (248 aa)
GCA_000518825_00532Unannotated protein. (51 aa)
atpHUnannotated protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (88 aa)
atpFUnannotated protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (175 aa)
atpEUnannotated protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (103 aa)
GCA_000518825_00536Unannotated protein. (30 aa)
GCA_000518825_00537Unannotated protein. (55 aa)
CK556_00620Unannotated protein. (73 aa)
GCA_000518825_00540Unannotated protein. (49 aa)
uppUnannotated protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (147 aa)
glyAUnannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (412 aa)
rpmG-2Unannotated protein; Belongs to the bacterial ribosomal protein bL33 family. (54 aa)
GCA_000518825_00580Unannotated protein. (67 aa)
GCA_000518825_00581Unannotated protein. (36 aa)
cysSUnannotated protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (179 aa)
rplIUnannotated protein; Binds to the 23S rRNA. (147 aa)
rpsRUnannotated protein; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (76 aa)
rpsFUnannotated protein; Binds together with S18 to 16S ribosomal RNA. (285 aa)
pthUnannotated protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (75 aa)
CK556_00450Unannotated protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (106 aa)
GCA_000518825_00601Unannotated protein. (33 aa)
GCA_000518825_00602Unannotated protein. (67 aa)
GCA_000518825_00603Unannotated protein. (52 aa)
GCA_000518825_00604Unannotated protein. (65 aa)
purAUnannotated protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (288 aa)
GCA_000518825_00624Unannotated protein. (48 aa)
CK556_00400Unannotated protein; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins. (48 aa)
CK556_00390Unannotated protein; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins. (157 aa)
GCA_000518825_00630Unannotated protein. (98 aa)
GCA_000518825_00635Unannotated protein. (85 aa)
CK556_00375Unannotated protein. (112 aa)
proCUnannotated protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (266 aa)
ackAUnannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (209 aa)
GCA_000518825_00662Unannotated protein. (164 aa)
ptaUnannotated protein. (322 aa)
GCA_000518825_00680Unannotated protein. (44 aa)
GCA_000518825_00681Unannotated protein. (129 aa)
metGUnannotated protein; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. (141 aa)
GCA_000518825_00683Unannotated protein. (81 aa)
GCA_000518825_00729Unannotated protein. (161 aa)
lysSUnannotated protein; Belongs to the class-II aminoacyl-tRNA synthetase family. (335 aa)
GCA_000518825_00747Unannotated protein. (129 aa)
serSUnannotated protein; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (156 aa)
GCA_000518825_00749Unannotated protein. (36 aa)
GCA_000518825_00829Unannotated protein. (60 aa)
tmkUnannotated protein; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (128 aa)
GCA_000518825_00860Unannotated protein. (34 aa)
nadEUnannotated protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (83 aa)
GCA_000518825_00862Unannotated protein. (54 aa)
rplSUnannotated protein; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (128 aa)
rpsPUnannotated protein; Belongs to the bacterial ribosomal protein bS16 family. (55 aa)
GCA_000518825_00927Unannotated protein. (159 aa)
GCA_000518825_00928Unannotated protein. (42 aa)
argSUnannotated protein. (178 aa)
frrUnannotated protein; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (105 aa)
GCA_000518825_00931Unannotated protein. (29 aa)
pyrHUnannotated protein; Catalyzes the reversible phosphorylation of UMP to UDP. (173 aa)
GCA_000518825_00933Unannotated protein. (55 aa)
tsfUnannotated protein; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (199 aa)
GCA_000518825_00936Unannotated protein. (38 aa)
rpsBUnannotated protein; Belongs to the universal ribosomal protein uS2 family. (111 aa)
GCA_000518825_00938Unannotated protein. (69 aa)
defUnannotated protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (103 aa)
thiIUnannotated protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (358 aa)
rpsDUnannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (201 aa)
tyrSUnannotated protein; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (153 aa)
GCA_000518825_00989Unannotated protein. (66 aa)
GCA_000518825_00990Unannotated protein. (70 aa)
GCA_000518825_00991Unannotated protein. (69 aa)
GCA_000518825_00992Unannotated protein. (54 aa)
GCA_000518825_00993Unannotated protein. (48 aa)
CK556_03295Unannotated protein; Belongs to the NAPRTase family. (71 aa)
GCA_000518825_00995Unannotated protein. (56 aa)
CK556_03300Unannotated protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (136 aa)
rplLUnannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (122 aa)
rplJUnannotated protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (166 aa)
rplAUnannotated protein; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (108 aa)
GCA_000518825_01044Unannotated protein. (107 aa)
rplKUnannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa)
GCA_000518825_01084Unannotated protein. (63 aa)
gltXUnannotated protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (150 aa)
GCA_000518825_01086Unannotated protein. (44 aa)
GCA_000518825_01087Unannotated protein. (55 aa)
GCA_000518825_01088Unannotated protein. (36 aa)
GCA_000518825_01091Unannotated protein. (106 aa)
pyrGUnannotated protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (114 aa)
GCA_000518825_01093Unannotated protein. (44 aa)
GCA_000518825_01094Unannotated protein. (63 aa)
rpmEUnannotated protein; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily. (92 aa)
GCA_000518825_01121Unannotated protein. (146 aa)
prfAUnannotated protein; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (214 aa)
rpsLUnannotated protein; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (107 aa)
rpsGUnannotated protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (101 aa)
GCA_000518825_01142Unannotated protein. (40 aa)
GCA_000518825_01143Unannotated protein. (51 aa)
fusAUnannotated protein; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (384 aa)
GCA_000518825_01145Unannotated protein. (134 aa)
GCA_000518825_01146Unannotated protein. (184 aa)
tufUnannotated protein; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (202 aa)
GCA_000518825_01182Unannotated protein. (61 aa)
GCA_000518825_01183Unannotated protein. (125 aa)
alaSUnannotated protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (322 aa)
CK556_02605Unannotated protein. (71 aa)
hptUnannotated protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (149 aa)
typAUnannotated protein. (576 aa)
lepAUnannotated protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (267 aa)
GCA_000518825_01221Unannotated protein. (259 aa)
proSUnannotated protein; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (203 aa)
GCA_000518825_01225Unannotated protein. (68 aa)
GCA_000518825_01230Unannotated protein. (174 aa)
asnSUnannotated protein. (231 aa)
GCA_000518825_01250Unannotated protein. (72 aa)
leuSUnannotated protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (79 aa)
GCA_000518825_01252Unannotated protein. (62 aa)
GCA_000518825_01253Unannotated protein. (40 aa)
rpsIUnannotated protein; Belongs to the universal ribosomal protein uS9 family. (131 aa)
rplMUnannotated protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (125 aa)
rplUUnannotated protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (99 aa)
rpmAUnannotated protein; Belongs to the bacterial ribosomal protein bL27 family. (95 aa)
GCA_000518825_01344Unannotated protein. (97 aa)
CK556_02475Unannotated protein. (258 aa)
GCA_000518825_01378Unannotated protein. (60 aa)
thyAUnannotated protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (92 aa)
fmtUnannotated protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (214 aa)
GCA_000518825_01403Unannotated protein. (41 aa)
efpUnannotated protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (98 aa)
GCA_000518825_01406Unannotated protein. (74 aa)
CK556_01690Unannotated protein. (212 aa)
pheSUnannotated protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (232 aa)
GCA_000518825_01476Unannotated protein. (47 aa)
GCA_000518825_01477Unannotated protein. (52 aa)
GCA_000518825_01478Unannotated protein. (172 aa)
GCA_000518825_01479Unannotated protein. (255 aa)
pheTUnannotated protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (258 aa)
rpmFUnannotated protein; Belongs to the bacterial ribosomal protein bL32 family. (59 aa)
GCA_000518825_01492Unannotated protein. (32 aa)
GCA_000518825_01493Unannotated protein. (29 aa)
GCA_000518825_01494Unannotated protein. (77 aa)
GCA_000518825_01495Unannotated protein. (35 aa)
ileSUnannotated protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (101 aa)
GCA_000518825_01497Unannotated protein. (54 aa)
GCA_000518825_01499Unannotated protein. (49 aa)
GCA_000518825_01498Unannotated protein. (96 aa)
CK556_02175Unannotated protein. (134 aa)
GCA_000518825_01500Unannotated protein. (84 aa)
thrSUnannotated protein; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (203 aa)
GCA_000518825_00019Unannotated protein. (53 aa)
GCA_000518825_00020Unannotated protein. (125 aa)
infCUnannotated protein; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (180 aa)
rpmIUnannotated protein; Belongs to the bacterial ribosomal protein bL35 family. (64 aa)
rplTUnannotated protein; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (41 aa)
trpSUnannotated protein; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (166 aa)
GCA_000518825_00043Unannotated protein. (92 aa)
CK556_01080Unannotated protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (90 aa)
CK556_01145Unannotated protein; Belongs to the CinA family. (152 aa)
smpBUnannotated protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (122 aa)
CK556_01240Unannotated protein. (208 aa)
CK556_01390Unannotated protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (145 aa)
glyQSUnannotated protein; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (117 aa)
GCA_000518825_00200Unannotated protein. (46 aa)
GCA_000518825_00201Unannotated protein. (100 aa)
aptUnannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa)
coaEUnannotated protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (83 aa)
GCA_000518825_00232Unannotated protein. (62 aa)
CK556_01540Unannotated protein. (181 aa)
rpsOUnannotated protein; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (88 aa)
infBUnannotated protein; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (629 aa)
CK556_01855Unannotated protein. (101 aa)
guaAUnannotated protein; Catalyzes the synthesis of GMP from XMP. (163 aa)
CK556_01885Unannotated protein; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (376 aa)
GCA_000518825_00373Unannotated protein. (121 aa)
GCA_000518825_00374Unannotated protein. (77 aa)
GCA_000518825_00375Unannotated protein. (29 aa)
GCA_000518825_00376Unannotated protein. (31 aa)
valSUnannotated protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (181 aa)
GCA_000518825_00378Unannotated protein. (43 aa)
GCA_000518825_00379Unannotated protein. (56 aa)
rpsUUnannotated protein; Belongs to the bacterial ribosomal protein bS21 family. (54 aa)
GCA_000518825_00395Unannotated protein. (46 aa)
GCA_000518825_00396Unannotated protein. (63 aa)
aspSUnannotated protein; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (324 aa)
hisSUnannotated protein. (314 aa)
rpsTUnannotated protein; Binds directly to 16S ribosomal RNA. (81 aa)
mtnNUnannotated protein; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (216 aa)
GCA_000518825_00410Unannotated protein. (69 aa)
nadDUnannotated protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (111 aa)
rpmGUnannotated protein; Belongs to the bacterial ribosomal protein bL33 family. (47 aa)
folDUnannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
GCA_000518825_00441Unannotated protein. (156 aa)
gatBUnannotated protein; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (284 aa)
CK556_00880Unannotated protein; Belongs to the amidase family. (482 aa)
rplQUnannotated protein. (48 aa)
rpsKUnannotated protein; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (65 aa)
GCA_000518825_00478Unannotated protein. (44 aa)
rpsMUnannotated protein; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (121 aa)
rpmJUnannotated protein; Belongs to the bacterial ribosomal protein bL36 family. (37 aa)
infAUnannotated protein; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (78 aa)
adkUnannotated protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (212 aa)
rplOUnannotated protein; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (145 aa)
rpsEUnannotated protein; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (205 aa)
rplRUnannotated protein; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (115 aa)
Your Current Organism:
Mesoplasma chauliocola
NCBI taxonomy Id: 1336232
Other names: M. chauliocola ATCC 49578, Mesoplasma chauliocola ATCC 49578
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