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| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (658 aa) |
| | galK_1 | LacI family transcriptional regulator; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (392 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (288 aa) |
| | pyrK | Dihydroorotate dehydrogenase electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (268 aa) |
| | pyrDB | Dihydroorotate dehydrogenase B catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (312 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (231 aa) |
| | ARC25797.1 | Inorganic pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (209 aa) |
| | dgkA | UDP kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (197 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (424 aa) |
| | murAB | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (419 aa) |
| | ligA | DNA ligase (NAD(+)) LigA; This protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa) |
| | nrdD_1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa) |
| | ARC25870.1 | Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa) |
| | guaA | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. (519 aa) |
| | tdk | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa) |
| | xpt | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (193 aa) |
| | guaC | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. (327 aa) |
| | yehU | Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa) |
| | ldhA | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (327 aa) |
| | plsY | Glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (215 aa) |
| | ARC25920.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa) |
| | ribD | Deoxycytidylate deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (434 aa) |
| | deoC1 | Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (220 aa) |
| | coaA | Type I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa) |
| | FlaR | Topology modulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa) |
| | srrB | Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (448 aa) |
| | glcK | Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa) |
| | carB | Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1059 aa) |
| | carA | Carbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (362 aa) |
| | pyrB | Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (306 aa) |
| | ndk | Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa) |
| | yutF | Hypothetical protein; Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro; Belongs to the HAD-like hydrolase superfamily. NagD family. (257 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (279 aa) |
| | ARC25993.1 | Choline kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa) |
| | proB | Glutamate 5-kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (99 aa) |
| | thiI | tRNA 4-thiouridine(8) synthase ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (404 aa) |
| | yqfL | Phosphoenolpyruvate synthase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (274 aa) |
| | ppdK | Pyruvate, phosphate dikinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (869 aa) |
| | yycG | Cell wall metabolism sensor histidine kinase VicK; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (158 aa) |
| | ARC26059.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa) |
| | rpiA | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (227 aa) |
| | tpiA_1 | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (252 aa) |
| | ptsI | Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (577 aa) |
| | plsC | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa) |
| | A6J72_01960 | ATPase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa) |
| | pspB | Histidine phosphatase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa) |
| | ARC26104.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa) |
| | ARC26106.1 | Sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa) |
| | bglK_1 | Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa) |
| | gmuB | PTS sugar transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (103 aa) |
| | ARC27412.1 | AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa) |
| | phoR | Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa) |
| | pgl | 6-phosphogluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa) |
| | ARC26141.1 | DNA gyrase subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa) |
| | ARC26152.1 | Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa) |
| | arcC1 | Carbamate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbamate kinase family. (315 aa) |
| | ARC26183.1 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa) |
| | pyrH | UMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa) |
| | nudF | ADP-ribose pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa) |
| | glmU | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (459 aa) |
| | graS | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa) |
| | tmk | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (212 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa) |
| | ppaC | Hypothetical protein; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa) |
| | ARC26261.1 | Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (724 aa) |
| | treB | PTS trehalose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (670 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (165 aa) |
| | butA | Aminoglycoside phosphotransferase APH(3'); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aminoglycoside phosphotransferase family. (267 aa) |
| | liaS | Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa) |
| | stkP | Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (624 aa) |
| | PppL | Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (208 aa) |
| | nadE | NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (274 aa) |
| | pncB2 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (486 aa) |
| | uppP | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (280 aa) |
| | desK_1 | Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa) |
| | fba | Fructose-1,6-bisphosphate aldolase, class II; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa) |
| | pyrG_1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa) |
| | ARC26396.1 | Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa) |
| | ARC26399.1 | HIT family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa) |
| | manX_1 | PTS mannose transporter subunit EIIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa) |
| | accA | Cytochrome O ubiquinol oxidase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (256 aa) |
| | accD | acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (287 aa) |
| | accC | acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (455 aa) |
| | fabZ | beta-hydroxyacyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (140 aa) |
| | yclM | Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (449 aa) |
| | cdh | CDP-diacylglycerol diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa) |
| | baeS | Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa) |
| | licB | PTS sugar transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa) |
| | pyrDA | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. (311 aa) |
| | pksG | hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa) |
| | mvaA | hydroxymethylglutaryl-CoA reductase, degradative; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HMG-CoA reductase family. (426 aa) |
| | ARC26494.1 | Phosphomevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa) |
| | MvaD | Diphosphomevalonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa) |
| | galK_2 | Mevalonate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa) |
| | thiN | Thiamine diphosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (219 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (503 aa) |
| | pgi | Glucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (449 aa) |
| | purA | Restriction endonuclease; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa) |
| | gph | HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa) |
| | ntpD | V-type ATP synthase subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane. (207 aa) |
| | ntpB | V-type ATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. (463 aa) |
| | ntpA | V-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (596 aa) |
| | ARC26583.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa) |
| | ARC26589.1 | PTS trehalose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (469 aa) |
| | bglK_2 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa) |
| | yfkJ | Phosphotyrosine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (142 aa) |
| | lytA | Cell wall-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa) |
| | lacD | Tagatose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldolase LacD family. (333 aa) |
| | manX_5 | PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa) |
| | levE_2 | PTS mannose transporter subunit IIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa) |
| | ARC26643.1 | Dihydroxyacetone kinase subunit L; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa) |
| | ARC26644.1 | Dihydroxyacetone kinase subunit DhaK; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa) |
| | ARC26646.1 | DhaKLM operon coactivator DhaQ; Similar to DhaK; in Lactococcus lactis this protein froms a stable complex with DhaS and activates transcription of the dha operon in the presence of dihydroxyacetone; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa) |
| | purB | Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa) |
| | purK | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (363 aa) |
| | purE | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (162 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (420 aa) |
| | purH | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (516 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (184 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (479 aa) |
| | purL | Phosphomethylpyrimidine kinase; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (1241 aa) |
| | purC | Phosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (235 aa) |
| | plsX | Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (332 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (322 aa) |
| | citS | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa) |
| | tpiA_2 | Triose-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa) |
| | guaB | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (493 aa) |
| | A6J72_05550 | Peptidoglycan-binding protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa) |
| | yihX | Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa) |
| | yjjG | Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa) |
| | cinA | CPBP family intramembrane metalloprotease; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (422 aa) |
| | cls | Cardiolipin synthase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (510 aa) |
| | cpsD | Tyrosine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa) |
| | pglD | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa) |
| | saeS | Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa) |
| | glcB | PTS mannose transporter subunit IIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (564 aa) |
| | ARC26814.1 | AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (212 aa) |
| | ARC26849.1 | Pyridoxamine 5-phosphate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa) |
| | gtaB | UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (338 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (147 aa) |
| | pgk | Phosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | ackA | SAM-dependent methyltransferase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa) |
| | cdsA | Phosphatidate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. (267 aa) |
| | desK_2 | Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa) |
| | manX_3 | PTS mannose/fructose/sorbose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa) |
| | relA | GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (738 aa) |
| | fcl | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (593 aa) |
| | kdgK | 2-keto-3-deoxygluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa) |
| | manX_4 | PTS N-acetylgalactosamine transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa) |
| | sorB | PTS N-acetylgalactosamine transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa) |
| | gpmA_1 | Histidine phosphatase family protein; Frameshifted; internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa) |
| | pdxK | Phosphomethylpyrimidine kinase; Catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa) |
| | pyrG_2 | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (536 aa) |
| | bglF | PTS beta-glucoside transporter subunit EIIBCA; Derived by automated computational analysis using gene prediction method: Protein Homology. (632 aa) |
| | gmuE | Fructokinase/branched chain amino acid--2-keto-4-methylthiobutyrate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (212 aa) |
| | ARC27086.1 | HD domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa) |
| | gnd | Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (474 aa) |
| | crr | PTS sugar transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa) |
| | ptsG | PTS glucose/maltose transporter subunit IIBCA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (729 aa) |
| | rdgB | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (328 aa) |
| | ARC27164.1 | NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Nudix hydrolase family. (149 aa) |
| | folD | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa) |
| | gpmA_2 | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (230 aa) |
| | lacD2 | Tagatose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldolase LacD family. (315 aa) |
| | lacC_2 | Phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (310 aa) |
| | lacE_2 | PTS lactose transporter subunit IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (567 aa) |
| | atpE | F0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (66 aa) |
| | atpB | F0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (237 aa) |
| | atpF | ATP synthase F0 subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (164 aa) |
| | atpH | F0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (178 aa) |
| | atpA | F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (501 aa) |
| | atpG | F0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (292 aa) |
| | atpD | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (468 aa) |
| | atpC | F0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (139 aa) |
| | murAA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (426 aa) |
| | ARC27266.1 | DNA-directed RNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (58 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa) |
| | lacC_1 | DeoR family transcriptional regulator; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. (297 aa) |
| | pfkA | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (336 aa) |
| | pyk | Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (500 aa) |
| | ribF | Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (310 aa) |
| | suhB | Inositol monophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa) |
| | prs2 | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (323 aa) |
| | yjbM | GTP pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa) |
| | ppnK | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (272 aa) |
| | coaBC_2 | Phosphopantothenoylcysteine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa) |
| | coaBC_1 | Phosphopantothenate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa) |
| | zwf | Spore gernimation protein GerA; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (495 aa) |
| | ARC27361.1 | NTP pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa) |
| | hprK | HPr kinase/phosphorylase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon [...] (310 aa) |
| | disA | TIGR00159 family protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (285 aa) |
| | glxK | Glycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (370 aa) |
| | udk | Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa) |
